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  • Involvement of PU.1 in NFATc1 promoter function in osteoclast development

    Ishiyama Kentaro , Okumura Ko , Ogawa Hideoki , Takasaki Yoshinari , Nishiyama Chiharu , Yashiro Takuya , Nakano Nobuhiro , Kasakura Kazumi , Miura Ryosuke , Hara Mutsuko , Kawai Fumitaka , Maeda Keiko , Tamura Naoto

    … Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. … NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient development of osteoclasts. …

    Allergology International 64(3), 241-247, 2015

    J-STAGE  Ichushi Web 

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