Search Results 1-20 of 86

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  • CXCR4 signaling contributes to alveolar bone resorption in <i>Porphyromonas</i> <i>gingivalis</i>-induced periodontitis in mice

    Nagashima Hidekazu , Shinoda Masamichi , Honda Kuniya , Kamio Noriaki , Hasuike Akira , Sugano Naoyuki , Arai Yoshinori , Sato Shuichi , Iwata Koichi

    … Although there was no significant difference in the mechanical sensitivity in the periodontal tissue between <i>P.g.</i> … Moreover, CXCR4 neutralization in the periodontal tissue following <i>P.g.</i> …

    Journal of Oral Science 59(4), 571-577, 2017

    J-STAGE  Ichushi Web 

  • Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors

    Alam Muntasir , Kuwata Takeo , Shimura Kazuya , Yokoyama Masaru , Ramirez Valdez Kristel Paola , Tanaka Kazuki , Maruta Yasuhiro , Oishi Shinya , Fujii Nobutaka , Sato Hironori , Matsuoka Masao , Matsushita Shuzo

    … Pseudoviruses with these mutations were prepared and used for the assessment of neutralization sensitivity to an array of antibodies. … The resulting neutralization data indicate that the potencies of some antibodies, especially of those against the CD4 binding site, V3 loop, and membrane-proximal external region epitopes, were increased by the mutations in gp41 that conferred resistance to the fusion inhibitors. …

    Retrovirology 13(1), 2016-09-27

    IR 

  • Sequential Injection Analysis for the Monitoring of Riverine Phosphorus and Iron Inputs into the Lagos Lagoon Sediments:Original Paper

    Oladosu Najeem , Zhao Kang , Abayomi Akeem , Olayinka Kehinde , Alo Babajide , Deng Anping

    … Sandwiched sample was found to offer higher sensitivity than a 2-zone stack for P SIA. … The combination of neutralization and dilution of bicarbonate extract prevented CO<sub>2</sub> …

    Journal of Flow Injection Analysis 33(1), 13, 2016

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  • Impact of the Maraviroc-Resistant Mutation M434I in the C4 Region of HIV-1 gp120 on Sensitivity to Antibody-Mediated Neutralization

    Boonchawalit Samatchaya , Harada Shigeyoshi , Shirai Noriko , Gatanaga Hiroyuki , Oka Shinichi , Matsushita Shuzo , Yoshimura Kazuhisa

    … We previously reported that a maraviroc (MVC)-resistant human immunodeficiency virus type 1variant, generated using in vitro selection, exhibited high sensitivity to several neutralizing monoclonal antibodies (NMAbs) and autologous plasma IgGs. … In this study, we examined the mutation most responsible for conferring enhanced neutralization sensitivity of the MVC-resistant variant to several NMAbs and autologous plasma IgGs. …

    Japanese Journal of Infectious Diseases 69(3), 236-243, 2016

    J-STAGE 

  • Development and Evaluation of an in-House IgM-Capture ELISA for the Detection of Chikungunya and Its Application to a Dengue Outbreak Situation in Kenya in 2013

    Wasonga Caroline , Inoue Shingo , Kimotho James , Morita Kouichi , Ongus Juliette , Sang Rosemary , Musila Lillian

    … To validate the in-house ELISA, 148 patient sera from the 2005 Comoros CHIK outbreak were tested with centers for disease control and prevention (CDC) IgM-capture ELISA (CDC ELISA) and focus reduction neutralization test (FRNT) as reference assays. … The in-house ELISA had a sensitivity of 97.6% and specificity of 81.3% compared to the CDC ELISA and a sensitivity of 91.1% and specificity of 96.7% compared to FRNT. …

    Japanese Journal of Infectious Diseases 68(5), 410-414, 2015

    IR  J-STAGE  Ichushi Web 

  • Evaluation of Rapid Neutralizing Antibody Detection Test against Rabies Virus in Human Sera

    Nguyen Kieu Anh Thi , Nishizono Akira , Nguyen Thu Tuyet , Nguyen Dong Vinh , Ngo Giang Chau , Nguyen Cam Nhat , Yamada Kentaro , Noguchi Kazuko , Ahmed Kamruddin , Hoang Hanh Duc

    … Rapid and easy determination of protective neutralization antibody (NAb) against rabies in the field is very important for an early and effective response to rabies in both animal and human health sectors. … The sensitivity, specificity, false negative rate, false positive rate and concordance of the RAPINA test as compared to RFFIT were 100%, 98.34%, 0%, 1.66% and 98.6%, respectively. …

    Tropical Medicine and Health 43(2), 111-116, 2015

    J-STAGE  Ichushi Web 

  • Emitter Current Sensor for Measuring Ion Generation Rate of Corona Discharge Air Ionizer

    Yoshioka Sayuri , Ikehata Takashi , Terashige Takashi , Hirata Yasuna , Okano Kazuo

    … An emitter current sensor was proposed in order to measure ion generation rates of corona discharge air ionizers aiming to investigate the effects of the operating condition on the neutralization performance. … A current sensor with high sensitivity is needed because the emitter current is small (nA or pA) and the voltage applied to the emitter is high (kilo volts). …

    IEEJ Transactions on Sensors and Micromachines 135(1), 7-12, 2015

    J-STAGE 

  • Evaluation of anti-<i>Treponema pallidum</i> antibody reagents based on recombinant antigens by latex agglutination test  [in Japanese]

    KOBAYASHI Ichizou , WAKUI Moe , YAMAMOTO Hiroyuki , TASAKI Ayako

    当院では,ラテックス凝集法のメディエースTPLA(極東製薬)を使用してきたが,偽陽性率が高く,乳びや溶血の影響があった.3社(富士レビオ,デンカ生研,シノテスト)のリコンビナント抗原を用いたTP抗体試薬を用いて測定を行った結果,再現性,プロゾーン試験などで良好な結果であった.感度,特異度が高く,FTA-ABS法に匹敵する特異度を持っていた.菌体精製抗原を用いたTP抗体試薬にかわって,リコンビナント …

    Japanese Journal of Medical Technology 63(6), 745-752, 2014

    J-STAGE  Ichushi Web 

  • Developing an Indirect ELISA Based on Recombinant Hexon Protein for Serological Detection of Inclusion Body Hepatitis in Chickens

    JUNNU Sucheeva , LERTWATCHARASARAKUL Preeda , JALA Siriluk , PHATTANAKUNANAN Sakuna , MOONJIT Pattra , SONGSERM Thaweesak

    … The specificity and sensitivity were 80 and 80%, respectively. … The correlation coefficient (r) of absorbance values from this ELISA compared with the serum neutralization test was 0.76. …

    Journal of Veterinary Medical Science 76(2), 289-293, 2014

    J-STAGE  Ichushi Web 

  • Development of a Focus-Reduction Neutralizing Test for Detecting Equine Herpesvirus Type-1-Neutralizing Antibodies

    BANNAI Hiroshi , NEMOTO Manabu , TSUJIMURA Koji , YAMANAKA Takashi , KONDO Takashi , MATSUMURA Tomio

    … We developed a focus-reduction neutralization test (FRNT) for EHV-1 using 96-well plates for faster large-scale testing with sufficient sensitivity. …

    Journal of Veterinary Medical Science 75(9), 1209-1212, 2013

    J-STAGE  Ichushi Web 

  • Relationship Between the Development Temperature and the Resist Characteristic of the Positive-Tone Novolak Resist  [in Japanese]

    SAITO Seiji , ISHIGURO Keita , TAKAHASHI Seiji , KONO Akihiko , SEKIGUTI Atsushi , TANIGUCHI Katsuto , TANAKA Hatsuyuki , HORIBE Hideo

    高分子論文集 69(11), 639-645, 2012-11-25

    References (11)

  • Relationship Between the Development Temperature and the Resist Characteristic of the Positive-Tone Novolak Resist  [in Japanese]

    SAITO Seiji , ISHIGURO Keita , TAKAHASHI Seiji , KONO Akihiko , SEKIGUTI Atsushi , TANIGUCHI Katsuto , TANAKA Hatsuyuki , HORIBE Hideo

    ノボラック系ポジ型レジストにおける現像温度(17.3℃~40.0℃)とレジスト特性との関係を検討した.レジストの初期膜厚とレジストの感度(<i>E</i><sub>th</sub>)との関係をSwing Curveにより評価し,レジスト特性に対する多重干渉波効果(Swing Curveの振幅)とバルク効果(Swing Curveの傾き)の影響を検討し …

    KOBUNSHI RONBUNSHU 69(11), 639-645, 2012

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  • Competitive ELISA for the Detection of Antibodies to Rift Valley Fever Virus in Goats and Cattle

    KIM Hyun-Joo , NAH Jin-Ju , MOON Jin-San , KO Young-Joon , YOO Han-Sang , KWEON Chang-Hee

    … The competitive ELISA (C-ELISA) could detect antibodies at 9-11 days after inoculation in goats and cattle with a sensitivity of 94.7% (virus neutralization titer >32) and specificity of 99.7%, respectively. …

    Journal of Veterinary Medical Science 74(3), 321-327, 2012

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  • Evaluation of Detection Sensitivity and Pre-enrichment Efficacy of [TA10] Pathogenic Bacterial Multiplex PCR Detection System Kit in Fruit and Vegetable Food Samples  [in Japanese]

    KAWASAKI Susumu , ZOU Bizhen , NAMBA Toyohiko , ARIMA Kazuhide , KIUCHI Isao , KAMISAKI-HORIKOSHI Naoko , KAWAMOTO Shinichi

    食中毒菌多重検出システム “[TA10] Pathogenic Bacterial Multiplex PCR Detection System” を用いて,果物・野菜からの検出法について評価した.16種類の果物・野菜を上記キットに供したところ,いずれも35±1℃, 22時間培養後の前培養液1 m<i>l</i> からMultiplex …

    Japanese Journal of Food Microbiology 28(4), 219-225, 2011

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  • Development of Novel In-Capillary Preconcentration Methods for Capillary Electrophoresis  [in Japanese]

    WU Xing-Zheng

    キャピラリー電気泳動(CE)分析の濃度検出感度の向上のため,幾つかのin-capillary濃縮法を開発した.まず,キャピラリー壁にひび割れを入れ,キャピラリー内で高電場領域とゼロ電場領域を設定した新規スッタキング法を検討した.次に,キャピラリーの先端に内径140 μmの透析膜を1 mm程度同軸接続し,タンパク質イオンをその透析膜内で濃縮してからCEを行う方法を検討した.また,キャピラリー壁 …

    BUNSEKI KAGAKU 57(2), 77-90, 2008-02-05

    J-STAGE  NDL Digital Collections  References (34)

  • pH-dependent gating of Kir2.1 inward rectifier potassium channel

    Ishihara Keiko , Yan Ding-Hong , Ehara Tsuguhisa

    … We then examined Kir2.1 mutant channels known to have reduced sensitivity to internal cationic blockers. … Neutralization of the acidic Glu residues situated on the wall of the cytoplasmic pore (E299S and E224G) neither notably affected the pH-dependent gating. … By contrast, neutralization of the acidic Asp residue on the wall of the transmembrane pore (D172N) abolished the gating. …

    Proceedings of Annual Meeting of the Physiological Society of Japan 2008(0), 075-075, 2008

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  • Structural basis for the two modes of the spermine block of the Kir2.1 channel

    Ishihara Keiko , Ehara Tsuguhisa , Yan Ding-Hong

    … In our previous study on the Kir2.1 channel, which is considered to be the predominant channel contributing to I<SUB>KIR</SUB>, we showed that high-affinity block by spermine causes the time-dependent gating, but that the channels mediating ∼10% of the maximum conductance show lower sensitivity to the spermine block and the outward currents flow through these channels. …

    Proceedings of Annual Meeting of the Physiological Society of Japan 2007(0), 226-226, 2007

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  • An experiment on the antibody titer in the blood of mongoose immunized with habu venom  [in Japanese]

    櫻井 秀樹 , 川島 由次 , 小倉 剛 [他] , 野崎 真敏 , 香村 昂男 , Sakurai Hideki , Kawashima Yoshitugu , Ogura Go , Nozaki Masatoshi , Kamura Takao

    ハブ毒の主要毒性因子の1つである出血毒素はその蛋白分子量の大きさ等により2つの主要な毒素因子である出血因子1(HR-1)と出血因子2(HR-2)に分けられる。マングースの血清中にはHR-1を中和するインヒビターが生得的にあることが知られている。しかしこの天然のインヒビターはHR-2に対しては中和能力をほとんど持たない。そこでマングースをハブ毒で免疫することによってHR-1とHR-2をバランスよく中 …

    The Science bulletin of the Faculty of Agriculture, University of the Ryukyus (53), 1-5, 2006-12

    IR  JASI  Cited by (1)

  • Analysis of Long-Range Transport of Aerosols with Water-Soluble Ionic Species and Trace Metal Components, Collected Continuously with Particle Size Segregation in the Coastal Area of the Sea of Japan : Focusing on the Kosa Event in Spring 2002  [in Japanese]

    HIOKI Tadashi , NAKANISHI Sadahiro , MUKAI Hitoshi , MURANO Kentaro

    … A high-sensitivity inductively coupled Argon plasma mass spectrometer was used for the trace metal analysis. … Sulfate and ammonium ions, present as (NH<SUB>4</SUB>)<SUB>2</SUB>SO<SUB>4</SUB>, were the major water-soluble inorganic ions in aerosol particles with the diameter of less than 2.5μm, indicating that neutralization had advanced greatly. …

    Earozoru Kenkyu 21(2), 160-175, 2006-06-20

    J-STAGE  References (28) Cited by (6)

  • Deposition of Tin-Dioxide Particle-Layers on Glass Substrates by the Electrospray Pyrolysis Method

    MATSUSHIMA Yuta , YAMAZAKI Tsutomu , MAEDA Kazuyuki , SUZUKI Takeyuki

    … In this work, the deposition mechanism is investigated in respect of the charge neutralization of the generated droplet/particle. … deposited onto glass substrates exhibited the high sensitivity against H<SUB>2</SUB>. …

    Preprints of Annual Meeting of The Ceramic Society of Japan<br>Preprints of Fall Meeting of The Ceramic Society of Japan 2003F(0), 42-42, 2003

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