Search Results 1-20 of 137

  • Efficacy of Emulsion Containing New Chitosan Derivative Applied to Infant Skin  [in Japanese]

    Akita-Furuhashi Mariko , Zaiki-Funamoto Kaori , Nakaoji Koichi , Hamada Kazuhiko , Yoshida Yasuhiro , Chiba Mami

    <p>乳幼児の皮膚は,成人と比較してバリア機能が未熟で乾燥しやすいため,保湿剤による日常的なスキンケアが必要である。そこで今回,両イオン性の両親媒性キトサン誘導体である部分ミリストイル化カルボキシメチルキトサン(<b>PMCMC</b>)を配合した <b>O/W </b>型乳液を開発し,乳幼児<b>28</b>名を …

    Hifu no kagaku 19(2), 138-143, 2020

    J-STAGE 

  • Particle Design Strategies for Developing Patient Centric Dosage Form Preparations  [in Japanese]

    Takeuchi Hirofumi

    … The topics will be divided into two parts, based on the type of particle: coarse particles (powder) and colloidal particles. … The former includes the preparation and characterization of functional particles prepared using a spray dryer. … Solid dispersions, solvent deposition particles and dry emulsion systems are described. …

    YAKUGAKU ZASSHI 140(8), 1013-1024, 2020

    J-STAGE 

  • Janus microspheres for enhanced enteral drug delivery: Preparation and orientated attachment to a Caco-2 monolayer

    Matsumoto Akihiro , Watanabe Chie , Murakami Masahiro

    … <p>Conventional oral preparations generally release incorporated drugs omnidirectionally, including into the lumen, leading to a low bioavailability of drugs that are unstable in the gastrointestinal tract. … The microspheres comprised a mucus-oriented hemisphere of an ammonioalkyl methacrylate copolymer and a protective hemisphere of a hard fat. …

    Drug Discoveries & Therapeutics 13(6), 343-353, 2019

    J-STAGE  Ichushi Web 

  • Preparation of Lipid Vesicles Using Double Emulsions  [in Japanese]

    KUROIWA Takashi , ICHIKAWA Sosaku

    <p>リン脂質などが水中で形成する脂質二分子膜が閉鎖小胞構造をとった脂質ベシクルは,ドラッグデリバリーシステムにおける薬剤キャリアや機能成分のカプセル化剤として利用できる分子集合体である。筆者らは,water-in-oil-in-water(W/O/W)型のダブルエマルションを基材とする脂質ベシクルの作製法を開発した。本法は,親水性物質を溶解した水滴を含むwater-in-oil(W/ …

    Oleoscience 19(5), 197-201, 2019

    J-STAGE  Ichushi Web 

  • Moisturizing Effect of Emulsion Containing Partially Myristoylated Carboxylmethyl-chitosan Applied to Dry Skin  [in Japanese]

    Yokoi Aya , Manabe Motomu , Noto Mai , Hasunuma Naoko , Nozawa Kazumi , Kawaguchi Naoko , Seino Haruyoshi , Okuda Makoto , Yoshida Yasuhiro

    <p>乾皮症に対して,保湿剤によるスキンケアが有用であることは広く周知されている。そこで今回,我々は同一分子内に両荷電を有する両親媒性キトサン誘導体である部分ミリストイル化カルボシキシメチルキトサン(以下 <b>PMCMC</b>)を配合した <b>O/W </b>型乳液を開発し,乾皮症を有する被験者<b>19</b&g …

    Hifu no kagaku 17(6), 347-353, 2018

    J-STAGE  Ichushi Web 

  • Preparation of nanocapsules containing organic dye by the phase inversion temperature method  [in Japanese]

    Kamezawa Miharu , Kinoshita Satoshi , Takaki Toshihiko , Ohzuno Yoshihiro , Takei Takayuki , Yoshida Masahiro

    有機色素とポリマーを組み込んだナノカプセルは近年では多くの関心を集めている。本研究では、低エネルギー乳化法の一つである転相温度乳化(Phase Inversion Temperature, PIT)法を用いたナノカプセル化有機色素を調製した。PIT法では、ポリオキシエチレン型非イオン性界面活性剤の温度特性を利用することで微細な液滴を有するO/Wナノエマルションを調製することができる。またこの液滴を …

    Studies in Science and Technology 7(2), 139-143, 2018

    J-STAGE 

  • Predictive Evaluation of Pharmaceutical Properties of Ulinastatin-Containing Vaginal Suppositories as a Hospital Preparation by Near-Infrared Spectroscopy

    Kishino Tohru , Inoue Yoshihiro , Inoue Kayoko , Saito Kenichi , Kondo Masami , Otsuka Kuniko , Terukina Takayuki , Hattori Yusuke , Otsuka Makoto

    … Because 2% surfactant was contained in S-55, the UTI injection solution formed a water-in-oil type emulsion as a suppository base. … Near (N) IR spectra of UTI suppositories were measured after mixing for 0–8 h. … The best calibration models to predict the HT and LOD of the suppositories were determined based on the NIR spectra by the leave-one-out method in a partial least-squares regression analysis (PLS). …

    Chemical and Pharmaceutical Bulletin 66(6), 589-595, 2018

    J-STAGE  Ichushi Web 

  • Preparation of Anion-exchange Fibers with Radiation-induced Emulsion Graft Polymerization for Rapid Protein Purification  [in Japanese]

    Kudo Daiki , Matuzaki Yuka , Kawai-Noma Shigeko , Umeno Daisuke , Saito Kyoichi

    <p>放射線乳化グラフト重合法を用いて,ポリエチレン繊維を基材とした抗体高速精製のためのアニオン交換吸着材(アニオン交換繊維)を作製した。グリシジルメタクリレート(GMA)をTween 20によって乳化させ,乳化グラフト重合を行った。続いて,グラフト鎖中のエポキシ基にジエチルアミンを付加した。ジエチルアミノ型アニオン交換繊維を高さ2.0 cmでカラムへ充填し,ウシ血清アルブミン(BSA …

    RADIOISOTOPES 66(7), 243-249, 2017

    J-STAGE  Ichushi Web 

  • Stability of Mixed Preparations Consisting of Commercial Moisturizing Creams with an Ointment Base Investigated by Magnetic Resonance Imaging

    Onuki Yoshinori , Funatani Chiaki , Yamamoto Yoshihisa , Fukami Toshiro , Koide Tatsuo , Hayashi Yoshihiro , Takayama Kozo

    … The present study was performed to investigate the stability of such preparations closely using magnetic resonance imaging (MRI). … As sample preparations, five commercial moisturizing creams that are popular in Japan were mixed with an ointment base, a white petrolatum, at a volume ratio of 1 : 1. …

    Chemical and Pharmaceutical Bulletin 65(5), 487-491, 2017

    J-STAGE  Ichushi Web 

  • Preparation of Oil-in-Water Emulsion with a Good Texture of Use and Waterproofness Using the Gemini Surfactant  [in Japanese]

    Sekiguchi Norio , Shimizu Katsuya

    使用感が良好で耐水性に優れたO/Wエマルジョン製剤の検討を行った。油と水の界面張力を下げるノニオン系界面活性剤を用いた乳化物は,使用感や再乳化され耐水性が悪いことから,物理的な力で(機械的に)乳化させ,乳化剤は少量で行うことができれば使用感も良好であると予測した。この機能を達成するにはジェミニ型の界面活性剤が適していると考え,ラウロイルグルタミン酸Naをリジンで連結させたジラウロイルグルタミン酸リ …

    Journal of Society of Cosmetic Chemists of Japan 51(1), 18-26, 2017

    J-STAGE 

  • Effect of Mixing Time and Storage Condition on Characterization of Heparinoid Admixtures with Corticosteroids  [in Japanese]

    Sugiyama Ikumi , Takahashi Namiki , Sadzuka Yasuyuki

    … In this study, we prepared admixtures of moisturizer with steroids and examined their usability and the amount of principal agent in formulations, particularly focusing on the moisturizer content. … In the examination of heparinoid amount, admixture A+E and B+E were mixed uniformly. … It was speculated that the emulsification of formulation C was broken. … The phenomenon was supported by the result of malleability. …

    YAKUGAKU ZASSHI 136(10), 1391-1400, 2016

    J-STAGE 

  • Preparation of Chitosan Microparticles by W/O Type Emulsion with Surfactant  [in Japanese]

    MAEDA Ryosuke , YOSHIDA Wataru , Tomita Rika

    Research Report of Kitakyushu National College of Technology 48, 71-74, 2015-01

  • Preparation and Characterization of Micro/Nano-emulsions Containing Functional Food Components

    WANG Zheng , NEVES Marcos A. , ISODA Hiroko , NAKAJIMA Mitsutoshi

    … Food Ingredients Journal of Japan(FFIジャーナル)219巻4号312-323頁(2014年)に掲載された原稿を,許可を得て,英訳したものである. …

    Japan Journal of Food Engineering 16(4), 263-276, 2015

    J-STAGE 

  • Preparation of O/I<sub>1</sub>-type Emulsions and S/I<sub>1</sub>-type Dispersions Encapsulating UV-Absorbing Agents

    Aramaki Kenji , Kimura Minami , Masuda Kazuki

    … A ternary phase diagram in a water/C<sub>12</sub>EO<sub>25</sub>/EHMC system at 25°C was constructed and the two-phase equilibrium of an oil phase and an I<sub>1</sub> … phase, which is necessary to prepare the O/I<sub>1</sub>-type emulsions, was confirmed. … Also, the melting of the I<sub>1</sub> …

    Journal of Oleo Science 64(8), 801-807, 2015

    J-STAGE 

  • Magnetic Resonance Imaging of the Phase Separation in Mixed Preparations of Moisturizing Cream and Steroid Ointment after Centrifugation

    Onuki Yoshinori , Funatani Chiaki , Yokawa Takashi , Yamamoto Yoshihisa , Fukami Toshiro , Koide Tatsuo , Obata Yasuko , Takayama Kozo

    … A mixed preparation consisting of a water-in-oil emulsion-type moisturizing cream and a steroid ointment is frequently prescribed for the treatment of atopic dermatitis. … We have investigated the compatibility of moisturizing creams and ointments because there are concerns regarding the physical stability of these mixed preparations. …

    Chemical and Pharmaceutical Bulletin 63(5), 377-383, 2015

    IR  J-STAGE  Ichushi Web 

  • Preparation of Monodisperse Emulsions in Three-Dimensional Microfluidic Devices Fabricated by Stereolithography

    Tsuchiya Masaki , Katakura Toru , Kanai Toshimitsu

    … In this report, we introduce our recent work on fabrication of three-dimensional microfluidic devices by stereolithography. … Stereolithography is a method to build a three-dimensional object layer by layer through the photopolymerization of a liquid monomer resin on the basis of computer-aided design (CAD) data. … Therefore, design of microfluidic devices with three-dimensional channels can be easily and efficiently performed. …

    Journal of the Society of Powder Technology, Japan 52(1), 17-24, 2015

    J-STAGE 

  • Painting Technique of Tamiji Kitagawa : Pre-Survey for Restoration of "A Boy at the Bible Reading" from the Kamiya Museum Collection  [in Japanese]

    白河 宗利 , 大久保 早希子 , 木島 隆康 , 森田 恒之 , 歌田 眞介

    愛知県立芸術大学紀要 = The bulletin of Aichi University of the Arts (45), 33-46, 2015

    IR  DOI 

  • Synthesis and Applications of Monolithic Ion Exchange Resin  [in Japanese]

    TAKADA Hitoshi , INOUE Hiroshi , NAKAMURA Akira , YAMANAKA Koji

    … We have synthesized a new type monolithic porous ion exchange resin which has a co-continuous porous structure. … In the first step, an open-celled porous styrene-divinylbenzene (St-DVB) copolymer is synthesized by preparation of waterin-oil (W/O) emulsion and polymerization. … The ion exchange capacities of the monolithic cation and anion exchange resins that have co-continuous porous structures were both over 4 meq/g. …

    Journal of Ion Exchange 25(4), 73-80, 2014

    J-STAGE 

  • Nano-Emulsions; Emulsification Using Low Energy Methods

    GOHTANI Shoichi , PRASERT Waraporn

    … The low-energy method can be classified into three categories: the Phase Inversion Temperature method, Phase Inversion Composition method or Emulsion Inversion Point method and the Spontaneous Emulsification method. … To study nano-emulsification using the low-energy methods, phase diagrams are used to determine the phase behavior of the components and specify the temperature and concentrations at which various structures exist at equilibrium with desired properties. …

    Japan Journal of Food Engineering 15(3), 119-130, 2014

    J-STAGE 

  • Preparation of Emulsions with Organoclay and the Application for Cosmetic Products  [in Japanese]

    SEKINE Tomoko

    … The mechanism of forming oil-gel was investigated. … Oil-gel viscosity was revealed to be influenced by the amount of surfactant adsorbed to organoclay, which controled the aggregation level of the clay particles. … Stable oil-in-water-in-oil type multiple emulsion was obtained by adding adequate amount of oil-in-water emulsion to the oil-gel. …

    Journal of the Clay Science Society of Japan (in Japanese) 52(3), 100-103, 2014

    J-STAGE 

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