Search Results 1-20 of 2690

  • The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion

    Nagai Yuma , Takayama Kaito , Nishitani Naoya , Andoh Chihiro , Koda Masashi , Shirakawa Hisashi , Nakagawa Takayuki , Nagayasu Kazuki , Yamanaka Akihiro , Kaneko Shuji

    … Background: Reward processing is fundamental for animals to survive and reproduce. … Conclusion: Our findings indicate that the activity of DRN 5-HT neurons projecting to the VTA is a key modulator of balance between reward and aversion. …

    International Journal of Molecular Sciences 21(6), 2020-03-21


  • The System of an Offering and a Reward in 8-9 Century  [in Japanese]

    佐藤 早樹子

    史観 = The historical review 182, 23-42, 2020-03



    … as the reward. …

    Journal of Architecture and Planning (Transactions of AIJ) (769), 699-705, 2020-03


  • An Adaptation of Pavlovian-to-Instrumental Transfer (PIT) Methodology to Examine the Energizing Effects of Reward-Predicting Cues on Behavior in Young Adults

    Raquel Quimas Molina da Costa , Emi Furukawa , Sebastian Hoefle , Jorge Moll , Gail Tripp , Paulo Mattos

    … During Pavlovian conditioning, slot machines appeared with one of two abstract symbols (cues), one symbol was predictive of monetary reward. … The results indicated increased effort on the instrumental task, i.e. higher response frequency and greater force, in the presence of the reward-predicting cue. …

    Frontiers in Psychology (11), 195, 2020-02-14


  • Deep Reinforcement Learning-Based Channel Allocation for Wireless LANs With Graph Convolutional Networks

    Nakashima Kota , Kamiya Shotaro , Ohtsu Kazuki , Yamamoto Koji , Nishio Takayuki , Morikura Masahiro

    … Furthermore, compared to the immediate reward maximization method, the proposed method successfully achieves greater reward channel allocation or realizes the optimal channel allocation while reducing the number of changes. …

    IEEE Access (8), 31823-31834, 2020-02-11


  • Striatal Beta Oscillation and Neuronal Activity in the Primate Caudate Nucleus Differentially Represent Valence and Arousal Under Approach-Avoidance Conflict

    Amemori Ken-ichi , Amemori Satoko , Gibson Daniel J. , Graybiel Ann M.

    … An approach-avoidance (Ap–Av) conflict arises when an individual has to decide whether to accept or reject a compound offer that has features indicating both reward and punishment. … In Ap–Av decision-making, reward and punishment differentially influence valence and arousal, allowing us to dissociate their neural processing. …

    Frontiers in Neuroscience (14), 2020-02-07


  • The Relationship of Subjective Reward for Stress Response on Human Service Profession  [in Japanese]

    井川 純一 , 徳岡 大 , 中西 大輔

    健康科学研究 = Studies in the health sciences 3(2), 61-74, 2020-02

    IR  DOI 

  • Relationships between interpretation bias of indirect requests and learning rate parameters for social reward or punishment  [in Japanese]

    平川 真

    電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 119(394), 41-45, 2020-01-25

  • Action control of a prefrontal cortex model based on hippocampal context-dependent input and reward-triggered synaptic plasticity in a contextual task  [in Japanese]

    田上 天羽 , 立野 勝巳

    電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 119(381), 23-26, 2020-01-23

  • Why the Fidget Spinner Is Popular? : Brain Activities Related to Pleasure of the Fidget Spinner  [in Japanese]

    西村 杏香 , 鳴川 紗 , 大野 維吹 , 久世 伊純 , 小林 耕太 , ニシムラ モモカ , ナルカワ スズカ , オオノ イブキ , クゼ イズミ , コバヤシ コウタ , Nishimura Momoka , Narukawa Suzuka , Ono Ibuki , Kuze Izumi , Kobayasi Kohta I

    ハンドスピナーは人気なおもちゃであり、世界中の人々がスピナーを回転させることが習慣になっている。この研究の目的は、他の依存症(アルコール,ギャンブルなど)に関連する脳活動とハンドスピナー使用中の脳活動を比較することで、人々がハンドスピナーにハマる理由を見つけることであった。そこで非磁性のハンドスピナーを作成し、核磁気共鳴画像によりスピナーを回している際の脳活動(脳血流)の変化を評価した。実験データ …

    同志社大学ハリス理化学研究報告 = The Harris science review of Doshisha University 60(4), 239-243, 2020-01

    IR  DOI 

  • Problems with Medical Fees and Ingenuity for the Management Caught by Child-Exclusive Home Visit Nursing Stations' Managers  [in Japanese]

    Okada Mari , Tomari Yuko , Endo Kinuyo , Ichikawa Yukari , Toriya Chisae , Akabane Akiko , Kanoya Yuka , Hamada Yuko

    <p>【目的】本研究の目的は,小児を専門的に支援している訪問看護ステーション(以下St.とする)の管理者が感じている診療報酬上の課題および経営上の工夫を明らかにし,小児の訪問看護を拡大・充実するための報酬のあり方について考察することである。<br>【方法】小児を専門的に訪問しているSt.の管理者にインタビュー調査を行い,質的に分析を行った。<br>【結果】対象と …

    Journal of Japan Society of Nursing Research, 2020


  • Detecting Reinforcement Learning-Based Grey Hole Attack in Mobile Wireless Sensor Networks

    GAO Boqi , MAEKAWA Takuya , AMAGATA Daichi , HARA Takahiro

    … In this study, we design reinforcement learning-based malicious nodes, and define a novel observation space and sparse reward function for the reinforcement learning. …

    IEICE Transactions on Communications E103.B(5), 504-516, 2020


  • Alcohol dependence and opioid receptor —Pharmacological profile of nalmefene—  [in Japanese]

    Ohgi Yuta

    <p>アルコールは,身近に存在する嗜癖性を有する物質であり,多量飲酒はアルコール依存症の発症につながりうる.アルコールをはじめ依存症形成に共通して重要と考えられているのは,脳内の報酬系回路といわれる中脳腹側被蓋野から側坐核に投射するドパミン神経系の活性化であり,側坐核におけるドパミンの遊離により快の情動が生じる.アルコール依存症においては,内因性オピオイドとその受容体であるオピオイド受 …

    Folia Pharmacologica Japonica 155(3), 145-148, 2020


  • Clinical study of GIRK channel inhibitors as candidate medicines for drug dependence  [in Japanese]

    Kotajima-Murakami Hiroko , Ikeda Kazutaka

    <p>近年,アディクションに関する話題は広くメディアなどを通じ報道されており,社会からの関心・認識が高まっている.また,「アディクションを治療する」ことは臨床現場の重要な課題となっている.アディクションには根治のための治療法がなく,長期にわたる通院や入退院,再使用の繰り返しがアディクションの治療現場の実状である.これらの現状を鑑みると,アディクションの根治を目指した新たな治療法の開発が …

    Folia Pharmacologica Japonica 155(3), 130-134, 2020


  • The Effect of Budget Culture on Target Ratcheting: An Empirical Research Based on Management Forecasts  [in Japanese]

    Hayakawa Sho , Senoo Takeyoshi , Yasukata Kenji , Arai Kohei , Yokota Eri

    <p>上司が部下に対して次期の目標値を設定する場合,今期の予実差がしばしば利用される.しかし,このような目標設定はラチェット効果を引き起こす可能性がある.上司はこれを緩和するために,部下に対する目標値を達成困難にしないというコミットメントを実行する必要がある.本研究の目的は,企業組織に固有の予算システムの特徴としての「予算文化」に注目し,その下位概念である「予算厳守」,「目標の難しさ」 …

    The Journal of Management Accounting, Japan 28(1), 19-36, 2020


  • Spying on neuromodulation by constructing new genetically encoded fluorescent sensors  [in Japanese]

    Li Yulong

    … <p>Monoamine transmitters, e.g. dopamine (DA), norepinephrine (NE) and serotonin (5-HT), are playing important roles in a plethora of physiological processes, including reward, attention and mood regulation. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-SL07, 2020


  • Roles of orexin neurons in motivated behaviors in rats  [in Japanese]

    Mizoguchi Hiroyuki , Inutsuka Ayumu , Katahira Kentaro , Yamada Kiyofumi , Yamanaka Akihiro

    … we established the gambling test for assessing reward motivation and decision-making under conditions of uncertainty, as well as a touch-screen system for assessing reward sensitivity and craving. Here, we examined the roles of orexin neurons in reward motivation and decision-making when orexin neurons are manipulated using pharmacogenetics approaches. In the gambling test for rodents, cell-specific excitatory manipulation of orexin neurons of rats using the DREADD technology resulted in …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-P-166, 2020


  • Optogenetic recording and manipulation of median raphe serotonin neurons in reward-related behavior.  [in Japanese]

    Kawai Hiroyuki , Nagai Yuma , Koda Masashi , Nagayasu Kazuki , Shirakawa Hisashi , Kaneko Shuji

    … <p>Reward processing is an essential function for survival of individuals. … Impairment in reward processing induces an objectively incorrect judgment about the value of reward, leading to drug addiction or anhedonia. … Increasing evidences implicate that serotonergic neurons as well as dopaminergic neurons play a critical role in the reward processing. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 1-YIA-28, 2020


  • Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors  [in Japanese]

    Funahashi Yasuhiro , Yura Yoshimitsu , Kuroda Keisuke , Nagai Taku , Amano Mutsuki , Yamada Kiyofumi , Kaibuchi Kozo , Ariza Anthony , Emi Ryosuke , Xu Yifan , Wei Shan , Kozawa Sachi , Ahammad Rijwan Uddin , Wu Mengya , Takano Tetsuya

    … <p>Dopamine (DA) activates MAPK via PKA/Rap1 in medium spiny neurons (MSNs) expressing the dopamine D1 receptor (D1R)in the nucleus accumbens (NAc), thereby regulating reward-related behavior.However, howMAPKregulates reward-relatedlearning and memory through gene expression is poorly understood. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 1-YIA-26, 2020


  • The cognitive function of the mice with an exonic deletion of RELN is impaired in touchscreen-based visual discrimination task  [in Japanese]

    Dong Geyao , Nagai Taku , Liao Jingzhu , Mori Daisuke , Wulaer Bolati , Nabeshima Toshitaka , Ozaki Norio , Yamada Kiyofumi

    … Mice were initially trained to discriminate between a pair of stimuli simultaneously displayed on the screen and received a liquid reward. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 1-SS-33, 2020


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