Search Results 1-20 of 159

  • Responses evoked in epithelial cells when their neighbor is dead  [in Japanese]

    米村 重信

    … The tight junction, one of typical cell-to-cell junctions regulates flow of substances through cell gaps in epithelial cell sheets. … It takes less than 1 hour to close the wound when only single cell is dead. … Tight junction components, ZO-1 and ZO-2 are known to be essential for tight junction formation. … Molecular analyses along this line would be essential for understanding the early signaling cascade leading to wound responses. …

    四国医学雑誌 77(1-2), 11-16, 2021-04-25


  • Fluorescent Nucleic Acid Systems for Biosensors

    Podder Arup , Lee Ha Jung , Kim Byeang Hyean

    … In particular, fluorescence-based nucleic acid systems have been studied extensively for their implementation in molecular biology as platforms for disease diagnosis. … We discuss single-nucleotide polymorphism–based molecular systems and their fluorescence behaviors in duplex DNA; … the use of double-stranded DNA and three-way junction–based molecular beacons (MBs) for the detection of biologically important mRNA and miRNA; …

    Bulletin of the Chemical Society of Japan 94(3), 1010-1035, 2021


  • Single-Molecule Conductance of a π-Hybridized Tripodal Anchor while Maintaining Electronic Communication

    Ohto Tatsuhiko , Tashiro Aya , Seo Takuji , Kawaguchi Nana , Numai Yuichi , Tokumoto Junpei , Yamaguchi Soichiro , Yamada Ryo

    … Direct hybridization between the π-orbital of a conjugated molecule and metal electrodes is recognized as a new anchoring strategy to enhance the electrical conductance of single-molecule junctions. … In this framework, π-conjugation is maintained in the molecular junction, and the tripodal structure makes the molecule stand upright on the metal electrode. … Molecular conductance is measured by the break junction technique. …

    Small, 2006709, 2020-12-18


  • Key Molecules to Decipher the Mechanisms of Intractable Neurological Diseases  [in Japanese]

    吉良 潤一

    … We used molecular immunopathology of autopsied materials to identify marked alterations in glial connexins (Cxs) in acute and chronic demyelinating lesions of MS as well as neuromyelitis optica (NMO) and Balóʼs concentric sclerosis. … Similar changes were also observed in acute and chronic experimental autoimmune encephalomyelitis (EAE), an animal model of MS. Glial Cxs form gap junction (GJ) channels, which connect glial cells constituting the glial syncytium. …

    福岡医学雑誌 = Fukuoka acta medica 111(3), 93-112, 2020-09-25

    IR  DOI 

  • Structural insights into gap junction channels boosted by cryo-EM

    Oshima Atsunori


    Current Opinion in Structural Biology (63), 42-48, 2020-08


  • STM apparent height measurements of molecular wires with different physical length attached on 2-D phase separated templates for evaluation of single molecular conductance

    Iizuka Tomoya , Shimizu Daiki , Matsuda Kenji

    Single molecular conductance of molecular wires is effectively evaluated by the combination of STM apparent height measurement and a 2-D phase separation technique. … Previously the method was only applied to a set of molecular wires with the same physical length, but herein we applied the method to thienylene-based and phenylene-based molecular wires with different physical lengths. …

    RSC Advances (10), 22054-22057, 2020-06-09


  • Graph Theoretical Study on the Conductivity of Single-Molecular Junctions Containing Heteroatoms  [in Japanese]

    OKAZAWA Kazuki , TSUJI Yuta , YOSHIZAWA Kazunari

    … <p>Single-molecule junctions have unique electron transport properties that are not found in solids or polymers. … Graph theoretical approaches have been used to predict whether conductivity in single-molecule junctions. … In this paper, the change in single-molecule conductivity when carbon atoms in alternant hydrocarbons are replaced with heteroatoms is investigated by using the graph-theoretic path-counting method. …

    Journal of Computer Chemistry, Japan 19(4), 158-160, 2020


  • Single-molecular bridging in static metal nanogap electrodes using migrations of metal atoms  [in Japanese]

    Naitoh Yasuhisa , Tani Yosuke , Koyama Emiko , Nakamura Tohru , Sumiya Touru , Ogawa Takuji

    <p>ナノスケールに向かい合った金属電極の間隔を原子移動により制御し、分子の結合基と金属を結合させる、新たな単一分子の架橋手法を開発した。これまで単一分子架橋構造の実現には、電極間隔を制御するための大きな周辺装置を素子毎に必要としていたが、今回電極間に外部電圧を印加するだけで達成した。この手法は、究極の微細化電子素子の一つと言われている単一電子デバイスへの貢献が期待される。</p …

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science 2020(0), 269, 2020


  • Temperature measurement of 1,4-benzendithiol single molecular junction by surface enhanced Raman scattering  [in Japanese]

    Yasuraoka Koji , Kaneko Satoshi , Nishino Tomoaki

    <p>単分子接合は分子素子への応用が期待されており、接合温度は性能評価の上で重要である。本研究では表面増強ラマン散乱(SERS)計測により1'4-ベンゼンジチオール(BDT)単分子接合の温度計測を試みた。BDT単分接合形成時におけるストークス及びアンチストークス散乱に由来したピーク強度比から温度を得た。加熱効果による温度上昇を検討したところ、レーザー強度に依存した接合温度の検出に成功し …

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science 2020(0), 263, 2020


  • Analysis of Raman spectra of spiropyran single-molecule junction using PCA  [in Japanese]

    Kobayashi Shuji , Kaneko Satoshi , Tamaki Takashi , Tsukagoshi Kazuhito , Nishino Tomoaki

    <p>金属電極間に機能性分子1つを架橋した単分子接合は,外部刺激による電気的特性の変化を利用した分子デバイスへの応用が期待されている.本研究では,スピロピランを架橋した単分子接合に電気伝導度とラマン分光の同時計測を適用し,電気的特性の変化の要因を検討した.主成分分析を用いスペクトルを解析した結果,開環体は閉環体より電気伝導度が高いことが示唆され,伝導度変化が分子の構造変化に由来すること …

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science 2020(0), 264, 2020


  • Identifying the molecular adsorption site of a single molecule junction through combined Raman and conductance studies

    加納 英明 , Satoshi Kaneko , Enrique Montes , Sho Suzuki , Shintaro Fujii , Tomoaki Nishino , Kazuhito Tsukagoshi , Katsuyoshi Ikeda , Hideaki KANOU , Hisao Nakamura , Héctor Vázquez , Manabu Kiguchi

    Single-molecule junctions are ideal test beds for investigating the fundamentals of charge transport at the nanoscale. … We report on a new methodology for characterizing the adsorption site of single-molecule junctions through the combination of surface enhanced Raman scattering (SERS), current–voltage (I–V) curve measurements, and density functional theory simulations. …

    Chemical science 10(25), 6261-6269, 2019-05


  • Control of molecular orientation in a single-molecule junction with a tripodal triptycene anchoring unit: toward a simple and facile single-molecule diode

    Fujii Shintaro , Ishiwari Fumitaka , Komoto Yuki , Su Lixinzhu , Yamagata Yuto , Kosaka Atsuko , Aiba Akira , Nishino Tomoaki , Fukushima Takanori , Kiguchi Manabu

    Japanese Journal of Applied Physics 58(3), 035003-035003, 2019-02-18


  • Single-molecule chiral recognition by STM using molecular tips  [in Japanese]

    Murakami Ryo , Nishino Tomoaki

    <p>キラル分子探針を用いたSTMに基づき,表面に吸着した単一分子のキラル識別法を開発することを目的とした.STMの金属探針にキラル分子を修飾した分子探針を作製した.試料として軸不斉を有するビナフチル誘導体(BINAP)を用い,Au表面に吸着させ実験に用いた.BINAP単一分子の電気伝導度を計測すると,そのキラリティに依存して異なる値が得られることが分かり,単一分子の光学識別が達成でき …

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science 2019(0), 3Da02, 2019


  • Room temperature UHV-STM study of single phthalocyanine molecules adsorbed on Cr(001)  [in Japanese]

    Sakai Yuta , Yamada Toyo Kazu

    <p>1nmサイズの単一分子デバイス開発は、次世代・超高密度化に向けて超高真空・走査トンネル顕微鏡(STM)による研究が盛んである。主に極低温で研究がされてきた。しかし、我々は、反強磁性Cr(001)基板を用いることで、室温でも、フタロシアニン分子(H<sub>2</sub>Pc)が熱拡散せず単一分子で安定に吸着することを確認した。吸着サイト制御、スピン偏極測定 …

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science 2019(0), 1P16, 2019


  • Large Conductance Variations in a Mechanosensitive Single-Molecule Junction

    Davide Stefani , Kevin J. Weiland , Maxim Skripnik , Chunwei Hsu , Mickael L. Perrin , Marcel Mayor , Fabian Pauly , Herre S. J. van der Zant

    … An appealing feature of molecular electronics is the possibility of inducing changes in the orbital structure through external stimuli. … This can provide functionality on the single-molecule level that can be employed for sensing or switching purposes if the associated conductance changes are sizable upon application of the stimuli. …

    Nano Letters 18(9), 5981-5988, 2018-08-22


  • Enhanced oxidation power in photoelectrocatalysis based on a micrometer-localized positive potential in a terrace hetero p-n junction  [in Japanese]

    Ahmad Mohd Fairus , Suzuki Motoya , Abe Toshiyuki , Nagai Keiji

    … Generally, p-n junction-based solar energy conversion has the disadvantage of a loss in potential gain in comparison with the photon energy. … In this study, we found a more positive potential for a lateral domain interface of p-n junction than for a conventional p-n junction. …

    NPG ASIA MATERIALS (10), 641, 2018-07-17


  • The effect of nitrogen lone-pair interaction on the conduction in a single-molecule junction with amine-Au bonding

    Sugita Yoshihiro , Taninaka Atsushi , Yoshida Shoji , Takeuchi Osamu , Shigekawa Hidemi , 谷中 淳 , 吉田 昭二 , 武内 修 , 重川 秀実

    … We have applied our previously developed three-dimensional dynamic probe method to analyze the conductance in a Au-/1,4-benzenediamine (BDA)/Au single molecule junction. …

    Scientific reports (8), 5222, 2018-03


  • Investigation on photochemistry of single molecular junction  [in Japanese]

    木口 学

    旭硝子財団助成研究成果報告 Reports of research assisted by the Asahi Glass Foundation, 1-13, 2018

  • The Investigation on Structural Change of BDT Single Molecular Junction by Continuous and Simultaneous Measurement of Electrical Conductance and SERS  [in Japanese]

    Kobayashi Shuji , Kaneko Satoshi , Kiguchi Manabu

    Meeting Abstracts of the Physical Society of Japan 73.2(0), 1988-1988, 2018


  • Water splitting reaction on single water molecular junction  [in Japanese]

    Kiguchi Manabu , Kaneko Satoshi

    Meeting Abstracts of the Physical Society of Japan 73.2(0), 1987-1987, 2018


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