Search Results 1-20 of 1666

  • Trend and risk factors of recurrence and complications after arrhythmias radiofrequency catheter ablation: a nation-wide observational study in Taiwan

    Lin Yuan , Wu Hsin-Kuan , Wang Te-Hsiung , Chen Tien-Hsing , Lin Yu-Sheng

    … Objectives: This study determined the recurrence and complication rates after radiofrequency catheter ablation (RFCA) for those with paroxysmal supraventricular tachycardia (PSVT), Wolff-Parkinson-White syndrome (WPW), atrial flutter (AFL), atrial fibrillation (AF) and ventricular tachycardia (VT). …

    BMJ Open 9(5), 2019-05


  • Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients

    Takaki Tadashi , Inagaki Azusa , Chonabayashi Kazuhisa , Inoue Keiji , Miki Kenji , Ohno Seiko , Makiyama Takeru , Horie Minoru , Yoshida Yoshinori

    … Induced pluripotent stem cells (iPSCs) from type 1 long QT (LQT1) patients can differentiate into cardiomyocytes (CMs) including ventricular cells to recapitulate the disease phenotype. … Single-cell analysis using a fast-responding dye confirmed that ventricular cells were the dominant subtype (control-iPSC-CMs: 98%, 88%, 91%; … In addition, LQT1-iPSC-ventricular cells displayed an increased frequency of early afterdepolarizations (p value = 0.031). …

    Stem Cells International (2019), 2019-03-06


  • Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice

    村越 伸行 , 許 東洙 , 田尻 和子 , 中川 嘉 , 島野 仁 , 野上 昭彦 , 小池 朗 , 青沼 和隆 , 家田 真樹 , Rujie Qin , Nobuyuki MURAKOSHI , Dong-Zhu XU , Kazuko TAJIRI , Duo Feng , Endin N. Stujanna , Saori Yonebayashi , Yoshimi NAKAGAWA , Hitoshi SHIMANO , Akihiko NOGAMI , Akira KOIKE , Kazutaka AONUMA , Masaki IEDA

    … Thus, we investigated the effects of exercise on cardiac function and ventricular arrhythmias in myocardial infarction (MI) induced heart failure mice. … Autonomic nervous system function and the incidence of spontaneous ventricular arrhythmia were evaluated via telemetry recording. … Compared with MI‐Sed, MI‐Ex, and MI‐βb showed decreased sympathetic tone and lower incidence of spontaneous ventricular arrhythmia. …

    Physiological Reports 7(4), e13972, 2019-02


  • Therapy-Resistant Ventricular Arrhythmias Developed More Often in Advanced Than in Therapeutic Mild Hypothermic Condition

    Saitoh Osamu , Watanabe Junya , Oikawa Ayaka , Sugai Ayari , Furushima Hiroshi , Chinushi Masaomi

    … <p>Therapy-resistant ventricular arrhythmias can occur during accidental advanced hypothermic conditions. …

    International Heart Journal, 2019


  • Effects of Angiotensin Receptor Neprilysin Inhibitors on Inducibility of Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy

    Huo Jun-Yu , Shan Qi-Jun , Jiang Wan-Ying , Chen Chu , Chen Ran , Ge Tian-Tian , Chang Qing , Zhu Lin , Geng Jie , Jiang Zhi-Xin

    … <p>The aims of the present study were to investigate the effects of angiotensin receptor neprilysin inhibitors (ARNi) on the susceptibility of ventricular arrhythmias (VAs) in rats with myocardial infarction (MI) and to explore the related mechanisms.</p><p>A total of 32 adult male Sprague-Dawley rats were divided into 3 groups: a control group, MI group, and MI+ARNi group. …

    International Heart Journal, 2019


  • Wearable cardioverter defibrillator for foreigners, a Tajikistani woman with ventricular fibrillation: a case report  [in Japanese]

    Ichimura Kenzo , Nishihara Masaaki , Mukai Yasushi , Uwatoku Toyokazu , Tokuda Kentaro , Akahoshi Tomohiko , Tsutsui Hiroyuki , Taguchi Tomoaki

    <p>近年,我が国では海外からの旅行者が急増し,外国人の救急搬送患者への対応に苦慮することが多い。今回,着用型自動除細動器(wearable cardioverter defibrillator, WCD)を有効に活用できた外国人旅行客の一例を報告する。症例はタジキスタン在住の72歳,女性。観光で訪日中に心室細動を発症,病院前にて自己心拍再開したが,当院搬送時は昏睡状態であった。緊急冠 …

    Journal of the Japanese Society of Intensive Care Medicine 26(5), 385-390, 2019


  • How Do We Establish Cardiac Sympathetic Nervous System Imaging with <sup>123</sup>I-<I>m</I>IBG in Clinical Practice? Perspectives and Lessons from Japan and the US

    Travin Mark I. , Matsunari Ichiro , Thomas Gregory S. , Nakajima Kenichi , Yoshinaga Keiichiro

    … Cardiac denervation is associated with progressive left ventricular (LV) dysfunction, ventricular arrhythmias, and sudden cardiac death (SCD) in heart failure (HF). … Recent multicenter trials have shown <sup>123</sup>I-<I>m</I>IBG to have strong predictive value for fatal arrhythmias and cardiac death in HF. …

    Annals of Nuclear Cardiology 5(1), 5-20, 2019


  • Mexiletine Suppressed Recurrent Ventricular Tachycardia Triggered by Hemodialysis in an Old Patient with LQT2

    Kang Yu , Wei Jiafu

    … We presented a 64-year-old woman who experienced recurrent ventricular arrhythmia after hemodialysis initiation because of end-stage renal disease. … The patient was beta-blocker nonresponder for ventricular arrhythmias suppression and experienced multiple ICD discharge. …

    International Heart Journal, 2019


  • Spiral Wave Reentry Control by Electrical Stimulus-Induced Virtual Electrode Polarization  [in Japanese]

    YATABE Junya , YAMAZAKI Masatoshi , SHIBATA Nitaro , TOMII Naoki , SAKUMA Ichiro , HONJO Haruo , HONMA Akihiko , ARAFUNE Tatsuhiko

    … <p>The main cause of arrhythmias is the reentry phenomenon. … Spiral wave reentry, a phenomenon of abnormal circulating excitation wave propagation, is speculated to be the cause of ventricular tachycardia (VT) and ventricular fibrillation (VF) . …

    Transactions of Japanese Society for Medical and Biological Engineering 57(2-3), 49-57, 2019


  • Atrial Arrhythmias and Atrial Involvement in Cardiac Sarcoidosis:Short Review with a Case Report

    Terasaki Fumio , Fujita Shuichi , Miyamura Masatoshi , Kuwabara Hiroko , Hirose Yoshinobu , Torii Ikuko , Nakamura Takahito , Hoshiga Masaaki

    … <p>Severe ventricular arrhythmias such as high-grade atrioventricular block and ventricular tachycardia may cause lethal conditions or sudden death in patients with cardiac sarcoidosis (CS). … As arrhythmias are being better diagnosed and treated, physicians are increasingly aware of atrial arrhythmias, which have not been focused upon as CS-related conditions, in patients with CS. …

    International Heart Journal 60(4), 788-795, 2019


  • Cardiac Arrest Associated with Both an Anomalous Left Coronary Artery and KCNE1 Polymorphism

    Kawai Hideki , Watanabe Eiichi , Ohno Seiko , Horie Minoru , Ozaki Yukio

    … <p>A 14-year-old boy collapsed suddenly after a basketball game and was transported to our hospital after recovering from ventricular fibrillation by an automated external defibrillator. … Transient myocardial ischemia may have exaggerated the instability from the arrhythmic substrate, even though KCNE1-D85N abnormalities alone are not thought to cause fatal arrhythmias. …

    International Heart Journal 60(4), 1003-1005, 2019


  • Development of cardiac tamponade and emergence of arrhythmia during chemotherapy for diffuse large B-cell lymphoma  [in Japanese]

    BABA Yuta , KABASAWA Nobuyuki , TSUKAMOTO Hiroyuki , UTO Yui , YANAGISAWA Kouji , HATTORI Norimichi , HARADA Hiroshi , NAKAMAKI Tsuyoshi , SAITO Bungo , SHIMADA Shotaro , SASAKI Yohei , MURAI So , ABE Maasa , FUJIWARA Shun , ARAI Nana , KAWAGUCHI Yukiko

    <p>心臓浸潤を伴う悪性リンパ腫は不整脈を含む様々な心合併症を併発する。症例は68歳男性。呼吸困難を主訴に受診し,心臓超音波検査で心タンポナーデと診断された。右房と右室に突出する腫瘤と胃壁の肥厚を認め,胃組織生検でびまん性大細胞型B細胞リンパ腫(diffuse large B-cell lymphoma, DLBCL)と診断した。心臓腫瘤があり,心嚢液中にリンパ腫細胞を認め,心臓浸潤を …

    Rinsho Ketsueki 60(6), 577-581, 2019


  • A case of phenytoin toxicity treated by extracorporeal cardiopulmonary resuscitation and hemadsorption for late onset refractory cardiac arrest  [in Japanese]

    Asaki Motohiro , Yamamori Nodoka , Masuda Takamitsu , Miki Yasuo

    <p>症例は37歳,男性。幼少期に交通外傷により前頭葉壊死となり人格障害,症侯性てんかんで近医にて投薬を受けていた。搬送前日,数剤の抗てんかん薬を含む処方薬,約40日分を過量服薬し意識障害遷延のため翌日に当院へ救急搬送された。昏睡であり胃内容物吸引・挿管施行し,集中治療を開始した。第4病日の朝に全身痙攣と,多源性心室固有調律,心室頻拍を認めショック状態となった。直流通電や強心薬の投与開 …

    Journal of the Japanese Society of Intensive Care Medicine 26(4), 259-263, 2019


  • Efficacy and Safety of the Ultra-Short-Acting β1-Selective Blocker Landiolol in Patients With Recurrent Hemodynamically Unstable Ventricular Tachyarrhymias ― Outcomes of J-Land II Study ―

    Ikeda Takanori , Yamashita Takeshi , The J-Land II Study Investigators , Shiga Tsuyoshi , Shimizu Wataru , Kinugawa Koichiro , Sakamoto Atsuhiro , Nagai Ryozo , Daimon Takashi , Oki Kaori , Okamoto Haruka

    … <p><b><i>Background:</i></b>We aimed to investigate the efficacy and safety of landiolol in Japanese patients with recurrent hemodynamically unstable ventricular tachycardia or recurrent ventricular fibrillation (recurrent VT/VF).</p><p><b><i>Methods and Results:</i></b>This was an open-label, uncontrolled, multicenter study. …

    Circulation Journal 83(7), 1456-1462, 2019


  • Long-Term Results of Intracardiac Mesenchymal Stem Cell Transplantation in Patients With Cardiomyopathy

    Yagyu Takeshi , Noguchi Teruo , Ohgushi Hajime , Kitamura Soichiro , Kangawa Kenji , Ogawa Hisao , Yasuda Satoshi , Nagaya Noritoshi , Doi Kaori , Nakatani Takeshi , Satomi Kazuhiro , Shimizu Wataru , Kusano Kengo , Anzai Toshihisa

    … Compared with baseline, there were no significant differences in B-type natriuretic peptide (BNP) (from 211 to 173 pg/mL), left ventricular ejection fraction (LVEF) (from 24% to 26%), and peak oxygen uptake (from 16.5 to 19.2 mL/min/kg) at 2 months. … During the follow-up period, no patients experienced serious adverse events such as arrhythmias. …

    Circulation Journal 83(7), 1590-1599, 2019


  • Echocardiographic Characteristics in Tetralogy of Fallot with Arrhythmia: Assessments Using 2D Speckle Tracking  [in Japanese]

    Ichikawa Naoko , Shiina Yumi , Kijima Yasufumi , Fukuda Terunobu , Niwa Koichiro

    <p><b>目的</b>:Fallot四徴症(Tetralogy of Fallot: TOF)術後遠隔期合併症として不整脈が問題になることが多い.不整脈発症の機序は肺動脈弁逆流による容量負荷,肺動脈狭窄による圧負荷や手術による心筋障害などが原因としてあげられる.右房,右室の容積や心室機能と予後との関連性についての報告はあるが,心房機能と不整脈発症の関連について …

    Japanese Journal of Medical Ultrasound Technology 44(3), 357-369, 2019


  • Carbamazepine intoxication complicated by status epilepticus and ventricular fibrillation in the youth ; a case report  [in Japanese]

    Fujii Ryo , Ano Masaki , Miyatake Satoru

    <p>症例はてんかんの既往があり不整脈リスクのない27歳男性で, 意識障害を主訴に救急搬送された。診療中に痙攣発作が出現し, 意識障害は遷延した。血中カルバマゼピン濃度高値であり, てんかん重積とカルバマゼピン中毒の疑いで入院とした。入院第4病日に心室細動が出現し, 蘇生処置により自己心拍再開が得られた。心室細動発症前の心電図モニターに著明なアーチファクトが混入していたことから, 痙攣 …

    KANTO Journal of Japanese Association for Acute Medicine 39(3), 363-365, 2019


  • Variation of Electrocardiogram Features Across Sleep Stages in Healthy Controls and in Patients with Sleep Apnea Hypopnea Syndrome

    Zeng Lingzi , Liang Jiuxing , Liao Yuanyuan , Zhou Guolin , Zhang Xiangmin , Luo Yuxi

    <p>Sleep apnea hypopnea syndrome (SAHS) is an independent risk factor for various cardiovascular diseases. Electrocardiogram (ECG) features such as the RR, PR, QT, QTc, Tpe intervals and the Tpe …

    International Heart Journal 60(1), 121-128, 2019

    J-STAGE  Ichushi Web 

  • Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice

    Prajapati Rajesh , Okumura Satoshi , Ishikawa Yoshihiro , Fujita Takayuki , Suita Kenji , Nakamura Takashi , Cai Wenqian , Hidaka Yuko , Umemura Masanari , Yokoyama Utako , Knollmann Björn C.

    … </p><p><b><i>Methods and Results: </i></b>In this study, the roles of Epac1 in the development of atrial and ventricular arrhythmias are examined. … In addition, we examined the usefulness of CE3F4, an Epac1-selective inhibitor, in the treatment of the arrhythmias in mice. … In calsequestrin2 knockout mice, Epac1 deficiency resulted in a reduction of ventricular arrhythmia. …

    Circulation Journal 83(2), 295-303, 2019


  • Variation of Electrocardiogram Features Across Sleep Stages in Healthy Controls and in Patients with Sleep Apnea Hypopnea Syndrome

    Zeng Lingzi , Liang Jiuxing , Liao Yuanyuan , Zhou Guolin , Zhang Xiangmin , Luo Yuxi

    <p>Sleep apnea hypopnea syndrome (SAHS) is an independent risk factor for various cardiovascular diseases. Electrocardiogram (ECG) features such as the RR, PR, QT, QTc, Tpe intervals and the Tpe …

    International Heart Journal, 2019


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