Search Results 1-20 of 2747

  • Interactions between kidney and liver in various disease condition  [in Japanese]

    古市 賢吾 , 沖野 一晃 , 横山 仁

    腎臓内科 = Nephrology 11(4), 417-424, 2020-04

  • Recent status of liver transplantation for acute liver failure in Japan  [in Japanese]

    中山 伸朗

    消化器・肝臓内科 = Gastroenterology & hepatology 7(3), 252-260, 2020-03

  • Acute-on-chronic liver failure and viral hepatitis/autoimmune hepatitis  [in Japanese]

    近藤 孝行 , 加藤 直也

    医学のあゆみ 272(7), 585-589, 2020-02-15

    Ichushi Web 

  • Autoimmune hepatitis with acute presentation  [in Japanese]

    吉澤 要

    日本臨床 = Japanese journal of clinical medicine 78(1), 150-155, 2020-01

    Ichushi Web 

  • Inhibitory Effects of Chitosan Oligosaccharide Supplementation on Acute Hepatic Injury Models  [in Japanese]

    竹之内 明子 , 小山 千尋 , 藤原 瑠香 , 平山 由佳里 , 國弘 明歩 , 藤田 菜穂 , 黒住 誠司 , 佐藤 公彦 , 岡本 芳晴 , 義澤 克彦

    キチン・キトサン研究 = Chitin and chitosan research 26(1), 29-41, 2020

  • THE CURRENT STATUS OF TRANSFUSION-TRANSMITTED HEPATITIS E VIRUS INFECTION IN JAPAN  [in Japanese]

    Tanaka Ami , Hoshi Yuji , Hasegawa Takashi , Sakata Hidekatsu , Furui Yasumi , Goto Naoko , Taira Rikizo , Matsubayashi Keiji , Satake Masahiro

    <p>E型肝炎ウイルス(HEV)の輸血感染対策を検討するため,輸血後E型肝炎感染患者として,既報(Transfusion 2017)の19例も含め,2018年までに判明した34症例について解析した.</p><p>原因献血者は全国に分布し,関東甲信越での献血者が半数以上を占めた.原因血液の88.2%(30例)がHEV RNA陽性かつHEV抗体陰性で,多くはHEV感 …

    Japanese Journal of Transfusion and Cell Therapy 66(3), 531-537, 2020

    J-STAGE 

  • A case of acute liver failure induced by hepatitis E virus in a patient with chronic alcoholic liver dysfunction  [in Japanese]

    Kobayashi Tomoe , Tanaka Shugo , Yokoyama Tatsuya , Matsumoto Shogo , Sarashina Koichiro , Kawahata Shuhei

    <p>症例は49歳男性.初診より2週間前からの倦怠感を自覚し,前医受診時に著明な黄疸,肝機能障害を指摘されるも入院治療を拒否し,外来にて経過観察となっていた.1週間後再診の際に急性肝不全の診断となり,当院紹介,入院加療を開始した.アルコール多飲歴があること,著明な黄疸,白血球増多,肝臓腫大の所見より重症アルコール性肝炎と診断し,ステロイド治療を開始したが,徐々に状態が悪化し,第30病日 …

    Kanzo 61(7), 374-381, 2020

    J-STAGE 

  • The First Case Report of Acute Symptomatic HEV Genotype 4 Infection in an HIV-positive Patient in Japan

    Kitaura Satoshi , Wakabayashi Yoshitaka , Okazaki Aiko , Okada Yuta , Okamoto Koh , Ikeda Mahoko , Okugawa Shu , Moriya Kyoji

    … <p>Hepatitis E virus (HEV) is a common cause of acute hepatitis. … We herein describe the case of a 50-year-old man with a history of human immunodeficiency virus (HIV) infection who was admitted with acute transaminitis. … To the best of our knowledge, this represents the first clinical case report of acute symptomatic HEV genotype 4 infection in an HIV-positive patient in Japan. …

    Internal Medicine 59(13), 1655-1658, 2020

    J-STAGE 

  • Fulminant Hepatitis due to <i>de novo</i> Hepatitis B after Cord Blood Transplantation Rescued by Medical Treatment

    Sano Tomoya , Kobayashi Masahiro , Suzuki Fumitaka , Kobayashi Mariko , Arase Yasuji , Ikeda Kenji , Kumada Hiromitsu , Akuta Norio , Suzuki Yoshiyuki , Kasuya Kayoko , Fujiyama Shunichiro , Kawamura Yusuke , Sezaki Hitomi , Hosaka Tetsuya , Saitoh Satoshi

    … <p>A 53-year-old man presented with fulminant hepatitis due to <i>de novo</i> … hepatitis B. … He had been diagnosed previously with adult T-cell leukemia (ATL) and previously resolved hepatitis B virus infection. … He developed fulminant hepatitis 18 months after CBT, 15 months after the withdrawal of immunosuppressants, and 10 months after vitreous injections of methotrexate for ATL-related retinal infiltration. …

    Internal Medicine 59(12), 1519-1524, 2020

    J-STAGE 

  • A fatal case of exacerbated liver cirrhosis caused by acute hepatitis E virus infection: atypical dynamics of anti-hepatitis E virus antibody titers  [in Japanese]

    Okano Hiroshi , Sase Tomohiro , Saito Tomonori , Mukai Katsumi , Nishimura Akira , Takahashi Masaharu , Okamoto Hiroaki , Asakawa Hiroki , Tsuruga Satomi , Nose Kenji , Tochio Tomomasa , Kumazawa Hiroaki , Isono Yoshiaki , Tanaka Hiroki , Matsusaki Shimpei

    <p>10年前に軽度の肝胆道系酵素値の異常を指摘されるも,その後医療機関受診がなかった72歳の男性が肝硬変による肝不全疑いで入院した.AMA-M2抗体陽性とIgM高値より原発性胆汁性胆管炎が肝硬変の原因と考えられた.保存的療法にて肝不全はやや改善したが,入院時血清よりIgA-HEV抗体とHEV RNAが検出されたことから,肝硬変にHEV感染を合併し肝不全に進展したものと診断された.HE …

    Kanzo 61(6), 326-334, 2020

    J-STAGE 

  • IgG4-related Autoimmune Hepatitis with a Suspected Drug-induced Etiology

    Kawabata Hideaki , Motoi Shigehiro , Enoki Yasuyuki , Minamikawa Tetsuhiro , Kawakatsu Yukino , Inoue Naonori , Okazaki Yuji , Sone Daiki , Yamaguchi Katsutoshi , Ueda Yuki , Hitomi Misuzu , Miyata Masatoshi

    … <p>A 69-year-old man was referred to our department with acute hepatitis. … Needle liver biopsy specimen showed interface hepatitis with mainly lymphocytic infiltration and bridging fibrosis in the periportal area. … Hepatitis recurred after the cessation of steroids; …

    Internal Medicine 59(11), 1401-1405, 2020

    J-STAGE 

  • Dehydrocholic Acid Ameliorates Sodium Taurocholate-Induced Acute Biliary Pancreatitis in Mice

    Zhang Xiaoyu , Li Youping , Zhang Junhua , Zhang Boli , Niu Hai , Huang Wen , Xin Guang , Li Shiyi , Wei Zeliang , Ming Yue , Yuan Jiyan , Wen E , Xing Zhihua , Yu Kui

    … <p>Acute biliary pancreatitis (ABP) with a high mortality rate is an incurable digestive system disease induced by abnormal bile acid regurgitation due to the biliary obstruction. … Dehydrocholic acid (DA) alleviates the severity of cholestatic hepatitis related to biliary inflammation, suggesting DA is potential to develop for the incurable ABP management. …

    Biological and Pharmaceutical Bulletin 43(6), 985-993, 2020

    J-STAGE 

  • A Case of Acute Exacerbation of Hepatitis B by Pembrolizumab for a Lung Adenocarcinoma Patient with Hepatitis B Surface Antigen  [in Japanese]

    Aoyama Masahiro , Hayashi Kazumi , Futamura Keisuke , Takashima Koji , Sashio Toyokazu , Tanikawa Yoshimasa

    <p><b>背景.</b>免疫チェックポイント阻害薬(immune checkpoint inhibitor:ICI)による様々な免疫関連の有害作用が知られているが,一方でICI投与においてのB型肝炎対策については確立していない.<b>症例.</b>54歳女性.肺腺癌で初回化学療法の治療前から経過中,B型肝炎のスクリーニングを行っていなか …

    Haigan 60(2), 115-119, 2020

    J-STAGE 

  • A case of stricture-type ischemic colitis from excessive alcohol consumption, with follow-up to rule out colon cancer

    Watahiki Yu , Saito Keietsu , Ishizaki Yuto , Yamanobe Kuniyoshi , Sagawa Keiichi , Abe Kazumichi , Ohira Hiromasa

    … <p>A 69-year-old man was admitted to Hanawa Kousei Hospital with acute hepatitis attributed to alcohol consumption. …

    FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 66(1), 60-65, 2020

    J-STAGE 

  • Hepatitis-associated Aplastic Anemia with Rapid Progression of Liver Fibrosis Due to Repeated Hepatitis

    Sawada Kenji , Ueda Yoshihide , Seno Hiroshi , Takai Atsushi , Yamada Tomoyo , Araki Osamu , Yamauchi Yuki , Eso Yuji , Takahashi Ken , Shindo Takero , Sakurai Takaki

    … <p>Hepatitis-associated aplastic anemia (HAAA) is a variant of acquired aplastic anemia and characterized by bone marrow failure that follows the development of acute hepatitis. … We herein report a rare case of HAAA with rapid progression of liver fibrosis due to repeated hepatitis. … Immunosuppressive therapy with cyclosporine effectively cured both the pancytopenia and hepatitis. …

    Internal Medicine 59(8), 1035-1040, 2020

    J-STAGE 

  • The first case of hepatitis E subgenotype 4c causing acute hepatitis E in Nagano Prefecture  [in Japanese]

    Yamagishi Masato , Terakawa Ion , Yamamoto Tomokiyo , Suzuki Naomi , Kiyosawa Kendo , Usuda Seiichi , Okamoto Hiroaki

    <p>症例は長野県在住で森林伐採業の62歳男性.全身倦怠感と食欲不振のため近医受診したところ肝酵素の著明な上昇があり紹介された.IgA/IgM HEV抗体,HEV RNAが陽性であり急性E型肝炎と診断した.HEV遺伝子株は4cであった.HEV 4c株によるE型肝炎は主として北海道・東北地方から報告されているが長野県では初めてである.本患者株の分子系統樹解析は北海道株に近接していた.患者 …

    Kanzo 61(4), 197-203, 2020

    J-STAGE 

  • A Rare Case of Von Meyenburg Complex (VMC) Diagnosed by Liver Biopsy during Cholecystectomy Associated with Acute Exacerbation of Chronic Cholecystitis in the Context of Chronic Hepatitis C  [in Japanese]

    Shinozaki Ryo , Kurio Katsumi , Takata Kiyoko , Takayama Tadatoshi

    von Meyenburg complex(以下 VMC)は肝内微小過誤腫であるが,臨床上比較的稀である.慢性 C 型肝炎経過観察中の慢性胆嚢炎急性増悪に対して胆嚢摘出術の際,同時に術中肝生検を施行して診断し得た VMCを経験した.症例は 53 歳男性.近医で慢性 C 型肝炎を経過観察されていた.胆嚢および肝組織の病理所見は,慢性胆嚢炎および肝組織は軽度線維化を認め,門脈域に胆管が不整に増生し,散 …

    Journal of Nihon University Medical Association 79(1), 29-33, 2020

    J-STAGE 

  • The prostaglandin E<sub>2</sub>-EP4 system protects the liver in Concanavalin A-induced hepatitis  [in Japanese]

    Imamichi Yoshitaka , Yuhki Koh-ichi , Kashiwagi Hitoshi , Kumei Shima , Nakanishi Katsura , Kojima Fumiaki , Narumiya Shuh , Ushikubi Fumitaka

    … <p>Concanavalin A (Con A) induces hepatitis in mice, an established model of acute immune-mediated hepatitis. … Therefore, we examined the role of the PGE<sub>2</sub>-EP4 system in Con A-induced hepatitis. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-O-018, 2020

    J-STAGE 

  • Immunosuppressive drugs to reduce the mortality rate in patients with moderate to severe paraquat poisoning: A Meta-analysis

    Gao Yan-Xia , Sun Chang-Hua , Che Lu , Zhang Yan , Wang Yi-Bo , Wan You-Dong , Sun Tong-Wen , Li Yi , Hou Lin-Lin , Sun Pei , Yuan Ding , Duan Guo-Yu

    … They were not associated with an increased incidence rate of hepatitis and reduced incidence rate of acute renal failure and hypoxia. …

    The Journal of Toxicological Sciences 45(3), 163-175, 2020

    J-STAGE 

  • Toxicological Property of Acetaminophen: The Dark Side of a Safe Antipyretic/Analgesic Drug?

    Ishitsuka Yoichi , Kondo Yuki , Kadowaki Daisuke

    … Hepatotoxicity is the greatest fault of APAP and the most frequent cause of drug-induced acute liver failure in Western countries. … Recent animal and cellular studies have demonstrated that some cellular events, such as c-jun N-terminal kinase (JNK) pathway activation, endoplasmic reticulum (ER) stress, and mitochondrial oxidative stress may play important roles in the development of hepatitis. …

    Biological and Pharmaceutical Bulletin 43(2), 195-206, 2020

    J-STAGE 

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