Search Results 1-20 of 46

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Anti-glomerular basement membrane (anti-GBM) disease [in Japanese]

森永裕士 , 杉山斉

腎臓内科 = Nephrology 13(3), 319-324, 2021-03
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Strategies for diagnosis and therapies in anti-glomerular basement membrane nephritis [in Japanese]

金子修三 , 臼井丈一 , 山縣邦弘

腎臓内科 = Nephrology 13(1), 52-61, 2021-01
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Anti-glomerular Basement Membrane Disease with Antiphospholipid Syndrome

Torigoe Miki , Obata Yoko , Kitamura Mineaki , Hara Shigeo , Fukuoka Junya , Nishino Tomoya

… Pulmonary alveolar hemorrhaging and a high level of anti-glomerular basement membrane (GBM) antibodies (700 IU/mL) were observed. … Based on her medical history and positive findings of serum lupus anticoagulant, anti-phospholipid antibody syndrome (APS) was suspected. …

Internal Medicine, 2021

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Anti-glomerular Basement Membrane Antibody Disease with Pulmonary Hemorrhage Alone and Seroconversion of Anti-glomerular Basement Membrane Antibodies 11 Months after Onset [in Japanese]

坂東賢二 , 村上城子 , 澤田智

日本小児科学会雑誌 = The journal of the Japan Pediatric Society 124(8), 1263-1269, 2020-08

Ichushi Web
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Treatment of Goodpasture syndrome double-seropositive for anti-glomerular basement membrane antibodies and anti-neutrophil cytoplasmic antibodies: case of a 10-year-old boy [in Japanese]

Takahashi Masaki , Kanemoto Katsuyoshi , Kobayashi Masayo , Masuda Mai , Kitamura Hiroshi , Matsumura Chieko

MPO-ANCA 陽性の Goodpasture 症候群の 10 歳男児例を経験した．当科入院 2 週間前からの倦怠感，食思低下を契機に腎機能障害(Cre 8.19 mg/dl)，抗 GBM 抗体・MPO-ANCA 陽性，さらに胸部 CT にて肺出血を示唆するスリガラス状陰影が発見され，前医より当科転院となった．血漿交換療法(PE)およびステロイドパルス療法にて肺病変の消失と抗体 …

Japanese journal of pediatric nephrology 33(2), 183-190, 2020

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Concomitant Nephrotic Syndrome with Diffuse Large B-cell Lymphoma: A Case Report

Kidoguchi Keisuke , Aoki Shigehisa , Kubota Yasushi , Ando Toshihiko , Kimura Shinya , Katsuya Hiroo , Ureshino Hiroshi , Kizuka-Sano Haruna , Yamaguchi Kyosuke , Nagata Ayako , Rikitake Shuichi , Aikawa Kanako , Naito Shinji

… Membranous nephropathy (MN) is a common glomerular disease that is characterized by diffuse thickening of the glomerular basement membrane, and a common cause of nephrotic syndrome (NS). … MN is often accompanied with malignant disease; …

The Tohoku Journal of Experimental Medicine 252(2), 153-157, 2020

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A case of rapidly progressive glomerulonephritis due to anti-glomerular basement membrane antibody disease in pregnancy [in Japanese]

鈴木正人 , 水主川純 , 村田周子 , 鈴木優人 , 金沢純子 , 佐藤陽一 , 川端伊久乃 , 小川正樹 , 田畑務 , 藤間千尋

東京産科婦人科学会会誌 68(3), 469-473, 2019-07

Ichushi Web
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Epitope recognized by anti-glomerular basement membrane (GBM) antibody in a patient with repeated relapse of anti-GBM disease

Nishibata Yuka , Masuda Sakiko , Nakazawa Daigo , Tanaka Satoshi , Tomaru Utano , Nergui Mandkhai , Xiao-yu Jia , Cui Zhao , Zhao Ming-hui , Nakabayashi Kimimasa , Ishizu Akihiro

Experimental and Molecular Pathology (107), 165-170, 2019-04

IR
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Treatment of rapidly progressive anti-GBM antibody-type glomerulonephritis with combination therapy involving simple plasma exchange and selective plasma exchange: a case report [in Japanese]

Yamatani Satoshi , Shirai Atsushi , Hirohata Yukiko , Kumamoto Nobuyuki , Kosaka Kyoko , Kikuta Junko , Fujii Hideki , Nishi Shinichi

新鮮凍結血漿 (FFP) を用いた単純血漿交換の代わりにアルブミン置換液を用いた選択的血漿交換が, 効率, 安全性, 医療費などの面から注目されている. 近年選択的血漿交換は, IgGである抗GBM抗体の除去は可能であるが, 少量だが凝固因子が除去される問題点がある. 80歳男性で, 抗糸球体基底膜抗体腎炎と診断した症例に対して, われわれはFFPでの単純血漿交換と選択的血漿交換 …

Nihon Toseki Igakkai Zasshi 51(9), 557-563, 2018

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A Case of Anti-Glomerular Basement Membrane Antibody-Positive Systemic Lupus Erythematosus with Pulmonary Hemorrhage Successfully Treated at an Early Stage of the Disease

Yamada Takehisa , Tsuruoka Shuichi , Mugishima Koji , Higo Seiichiro , Yoshida Yukie , Itagaki Fumiaki , Yui Shizuka , Kashiwagi Tetsuya , Endo Yoko , Shimizu Akira

… We report here a case of systemic lupus erythematosus (SLE) with pulmonary hemorrhage and anti-glomerular basement membrane (anti-GBM) antibodies. … Serological tests revealed elevated titers of serum anti-GBM antibodies, proteinase 3-antineutrophil cytoplasmic antibodies (PR3-ANCA), and anti-double stranded deoxyribonucleic acid (dsDNA)-immunoglobulin G (IgG) antibodies. …

Journal of Nippon Medical School 85(2), 138-144, 2018

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Effectiveness of Plasmapheresis in a Patient with Anti-glomerular Basement Membrane Antibody Glomerulonephritis with Advanced Kidney Dysfunction

Usui Toshiaki , Kai Hirayasu , Noguchi Kazuyuki , Morito Naoki , Usui Joichi , Saito Chie , Uesugi Noriko , Nagata Michio , Yamagata Kunihiro

… Patients with anti-glomerular basement membrane antibody glomerulonephritis (anti-GBM GN) have severe kidney dysfunction, leading to end-stage renal disease. … The effect of plasmapheresis and immunosuppressive treatment in patients with severe glomerular changes is controversial. …

Internal Medicine 56(18), 2475-2479, 2017

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Anti-glomerular basement membrane nephritis concurrent with lupus nephritis [in Japanese]

Shimoda Saeko , Oka Kazumasa , Miki Sho , Taniguchi Keisuke , Hagihara Kouichirou , Fumihara Daiki , Iwanari Sachio , Ikeda Masaki , Tanaka Mari , Takeoka Hiroya

症例は43歳, 男性. 8年前にループス腎炎Ⅴ型と診断されたが, 治療によりネフローゼ症候群は完全寛解した. 2014年4月にネフローゼ症候群の再燃と急性腎障害を認めたため入院となった. 入院時に抗糸球体基底膜抗体が陽性で腎生検で半月体形成性糸球体腎炎であったが, 糸球体基底膜にIgGの線状沈着を認めず, ループス腎炎Ⅳ＋Ⅴ型としてステロイド投与を開始した. 単純血漿交換療法も併用し …

Nihon Toseki Igakkai Zasshi 49(12), 833-839, 2016

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Rapidly Progressive Renal Dysfunction in Two Elderly Patients with Renal Enlargement and Medullary Cystic Kidney Disease-like Acute Tubulointerstitial Injury

Kawamoto Shinya , Koda Ryo , Yoshino Atsunori , Takeda Tetsuro , Ueda Yoshihiko

… Medullary cystic kidney disease (MCKD) is a hereditary disease associated with bilateral medullary polycysts and interstitial fibrosis. …

Internal Medicine 55(20), 3001-3007, 2016

J-STAGE Ichushi Web
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Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Negative Small Vessel Vasculitis: A Rare Cause of Pulmonary Renal Syndrome

Munshi Boudhayan Das , Sengupta Sarbani , Sharan Abhijeet , Mukhopadhyay Sarmishtha , Ghosh Bhaskar , Dasgupta Angira , Bhattacharyya Rana

… Several immunologic and non-immunologic mechanisms including anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis, anti-glomerular basement membrane disease, and systemic lupus erythematosus are commonly involved in the pathogenesis of the syndrome. … An early diagnosis of this disease and its timely intervention is crucial. …

Internal Medicine 54(21), 2759-2763, 2015

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Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies

Liu Ning , Shi Junfeng , Xiao Ying , Yasue Misato , Takei Yoshinori , Sanefuji Hayato , Tsujimoto Gozoh , Hirasawa Akira

… Glomerulonephritis (GN) is a set of pathological conditions that result in the destruction of glomeruli and loss of renal function, commonly leading to the development of end-stage renal disease. … In the present study, we found a novel antinephritic effect of a tricaprylin emulsion in the anti-glomerular basement membrane (anti-GBM) GN rat model. …

Biological and Pharmaceutical Bulletin 38(8), 1175-1184, 2015

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Apheresis Therapy for Anti-glomerular Basement Membrane Antibody Disease [in Japanese]

Mochizuki Kaori , Ito Takafumi

… Anti-glomerular basement membrane (GBM) antibody disease is a relatively rare autoimmune disorder in which glomerulus and/or pulmonary capillary are injured by an anti-GBM antibody that binds to be basement membrane. …

日本アフェレシス学会雑誌 34(2), 126-130, 2015

NDL Digital Collections Ichushi Web
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Progress of Apheresis for Renal Disease [in Japanese]

Kitagawa Kiyoki , Furuichi Kengo , Wada Takashi

… Anti-neutrophil cytoplasmic antibodies (ANCA) and anti-glomerular basement membrane (GBM) antibodies are thought to be involved in the clinical condition of RPGN. … Treatment with immunosuppressive therapy plus plasma exchange, which directly removes ANCA or anti-GBM antibodies, has improved the outcome of patients with RPGN. …

日本アフェレシス学会雑誌 33(2), 117-122, 2014

NDL Digital Collections Ichushi Web
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A case of acute kidney injury associated with anti-glomerular basement membrane antibody disease and thrombotic microangiopathy [in Japanese]

OOKUBO Aiko , SHIMIZU Yuka , IRIFUKU Taisuke , NAITO Takayuki , OGAWA Takahiko , MASAKI Takao

症例は73歳，女性．発熱，全身倦怠感，無尿，食欲不振，浮腫のため県立広島病院腎臓内科に入院した．第1病日に抗菌薬投与と血液透析（HD）を行った．しかしながら症状は改善せず，第6病日に正球性正色素性貧血，血小板減少，高LDH血症が出現した．第8病日ハプトグロビン感度以下，直接および間接Coombs試験陰性，末梢血に破砕赤血球を認め，血栓性微小血管障害症（TMA）と診断し，単純血漿交換療法（PE）を開 …

Nihon Toseki Igakkai Zasshi 45(10), 973-978, 2012-10-28

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Dense deposit disease in a 6-year-old girl [in Japanese]

Yamada Takuji , Gotoh Yoshimitsu , Kuroyanagi Yoshiyuki , Tanaka Kazuki

… 初回と同様，重度な分節性壊死性腎炎像であったが，Humpも認め，初回腎生検の電顕上基底膜内に高電子密度沈着物が観察されておりdense deposit disease(DDD)と診断した。 …

Nihon Shoni Jinzobyo Gakkai Zasshi 25(2), 148-152, 2012

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A case of rapidly progressive glomerulonephritis with both MPO-ANCA and anti-GBM antibodies complicated by thrombotic thrombocytopenic purpura [in Japanese]

YOSHIHARA Mayumi , HASEGAWA Koichi , OBARA Fumio

症例は73歳，男性．2008年7月発熱，尿蛋白および尿潜血反応陽性，血清Cr値の上昇（0.9→2.3 mg/dL）を認め当科入院となった．ミエロペルオキシダーゼ抗好中球細胞質抗体（MPO-ANCA）が83 EUと高値で，腎生検上pauci-immune型半月体形成性糸球体腎炎の所見を認めたことから，MPO-ANCA関連急速進行性糸球体腎炎（RPGN）と診断し，methylprednisolone（ …

Nihon Toseki Igakkai Zasshi 44(5), 463-467, 2011-05-28

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