Search Results 1-20 of 93970

  • The multiple functions and subpopulations of eosinophils in tissues under steady-state and pathological conditions

    Kanda Akira , Asako Mikiya , Iwai Hiroshi , Yun Yasutaka , Bui Dan Van , Nguyen Linh Manh , Kobayashi Yoshiki , Suzuki Kensuke , Mitani Akitoshi , Sawada Shunsuke , Hamada Satoko

    … for example, eosinophils contribute to adipose tissue metabolism and metabolic health through alternatively activated macrophages and the maintenance of plasma cells in intestinal tissue and bone marrow. …

    Allergology International 70(1), 9-18, 2021

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  • Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure

    Kanno Takashi , Adachi Yoshiyuki , Ohashi-Doi Katsuyo , Matsuhara Hiroki , Hiratsuka Rie , Ishibashi Ken-ichi , Yamanaka Daisuke , Ohno Naohito

    … The cytokine production by bone marrow-derived DCs (BMDCs) obtained from wild-type and BG receptor (dectin-1) knock-out mice was examined <i>in vitro</i>. …

    Allergology International 70(1), 105-113, 2021

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  • Acquired amegakaryocytic thrombocytopenia after durvalumab administration

    Suyama Takahiro , Hagihara Masao , Kubota Naoto , Osamura Yoshiyuki , Shinka Yoko , Miyao Naoki

    … Acquired amegakaryocytic thrombocytopenic purpura (AATP) is an unusual disorder characterized by thrombocytopenia with markedly diminished bone marrow megakaryocytes in the presence of otherwise normal hematopoiesis. … Bone marrow biopsy showed scarce megakaryocytes (< … After recovery, bone marrow aspiration revealed a normal number of megakaryocytes. …

    Journal of Clinical and Experimental Hematopathology, 2021

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  • A Case of Electrical Burn with Bone Injury on the Head  [in Japanese]

    Sakagami Akihiko , Daizo Haruhisa , Higashiyama Maiko

    Japanese Journal of Surgical Wound Care 12(1), 18-21, 2021

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  • Asfotase alfa has a limited effect in improving the bowed limbs in perinatal benign hypophosphatasia: A case report

    Matsushita Masaki , Mishima Kenichi , Nagata Tadashi , Kamiya Yasunari , Imagama Shiro , Kitoh Hiroshi

    … <p>Hypophosphatasia (HPP) is a rare skeletal dysplasia characterized by impaired bone mineralization, caused by loss-of-function mutations in the tissue-nonspecific alkaline phosphatase (<i>TNSALP</i>) gene. … Enzyme replacement therapy (ERT) by administration of asfotase alfa was reported to improve the survival rate, bone mineralization, and short stature in the severe form of HPP. …

    Clinical Pediatric Endocrinology 30(1), 53-56, 2021

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  • Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study

    Hozawa Atsushi , Sasaki Ryohei , Takanashi Nobuyuki , Otsuka Kotaro , Sakata Kiyomi , Kuriyama Shinichi , Kikuya Masahiro , Tanabe Osamu , Sugawara Junichi , Suzuki Kichiya , Suzuki Yoichi , Tanno Kozo , Kodama Eiichi N , Fuse Nobuo , Kiyomoto Hideyasu , Tomita Hiroaki , Uruno Akira , Hamanaka Yohei , Metoki Hirohito , Ishikuro Mami , Obara Taku , Kobayashi Tomoko , Nakaya Naoki , Kitatani Kazuyuki , Takai-Igarashi Takako , Ogishima Soichi , Satoh Mamoru , Ohmomo Hideki , Tsuboi Akito , Egawa Shinichi , Ishii Tadashi , Ito Kiyoshi , Ito Sadayoshi , Nakamura Tomohiro , Taki Yasuyuki , Minegishi Naoko , Ishii Naoto , Nagasaki Masao , Igarashi Kazuhiko , Koshiba Seizo , Shimizu Ritsuko , Tamiya Gen , Nakayama Keiko , Motohashi Hozumi , Tsuchiya Naho , Yasuda Jun , Shimizu Atsushi , Hachiya Tsuyoshi , Shiwa Yuh , Tominaga Teiji , Tanaka Hiroshi , Oyama Kotaro , Tanaka Ryoichi , Kawame Hiroshi , Fukushima Akimune , Hirata Takumi , Ishigaki Yasushi , Tokutomi Tomoharu , Osumi Noriko , Kobayashi Tadao , Nagami Fuji , Hashizume Hiroaki , Arai Tomohiko , Kawaguchi Yoshio , Higuchi Shinichi , Sakaida Masaki , Narita Akira , Endo Ryujin , Nishizuka Satoshi , Tsuji Ichiro , Hitomi Jiro , Nakamura Motoyuki , Ogasawara Kuniaki , Yaegashi Nobuo , Kinoshita Kengo , Kure Shigeo , Sakai Akio , Kogure Mana , Kobayashi Seiichiro , Sobue Kenji , Sasaki Makoto , Yamamoto Masayuki , Nochioka Kotaro

    … We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. …

    Journal of Epidemiology 31(1), 65-76, 2021

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  • How much platelet-rich plasma can be soak-loaded onto beta-tricalcium phosphate? A comparison with or without a unidirectional porous structure

    Arai Norihito , Yoshioka Tomokazu , Sugaya Hisashi , Kanamori Akihiro , Yamazaki Masashi

    … The volume ratios of PRP soak-loaded onto the artificial bone and soaked area ratios were evaluated. …

    Journal of Rural Medicine 16(1), 14-21, 2021

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  • Concentrated autologous bone marrow aspirate transplantation versus conservative treatment for corticosteroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus

    Tomaru Yohei , Yoshioka Tomokazu , Nanakamura Junichi , Sugaya Hisashi , Hagiwara Shigeo , Nawata Kento , Ohtori Seiji , Yamazaki Masashi , Mishima Hajime

    … To compare the outcomes of steroid-associated osteonecrosis of the femoral head in patients with systemic lupus erythematosus who underwent conservative treatment and concentrated autologous bone marrow aspirate transplantation</p><p><b>Methods:</b> …

    Journal of Rural Medicine 16(1), 1-7, 2021

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  • Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series

    Kikuchi Naoya , Yoshioka Tomokazu , Taniguchi Yu , Kanamori Akihiro , Yamazaki Masashi

    … Unidirectional porous β-tricalcium phosphate (UDPTCP) consists of a novel porous artificial bone that is structurally different from conventional artificial bone comprised of spherical porous β-tricalcium phosphate (SPTCP).</p><p><b>Case presentation:</b> …

    Journal of Rural Medicine 16(1), 52-55, 2021

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  • A case of Noonan syndrome with skull defect due to vitamin D deficiency rickets

    Nagara Syunsuke , Usui Shinji , Kawashiri Miwa , Kondo Masashi , Yamagishi Atsushi

    … At 77 d of age, clinical examination of the head revealed widespread craniotabes of the occipital region centered around the lambda suture, and palpation revealed a defect of about 1 cm in the parietal bone of the left occipital region. … Cranial computed tomography showed thinning of the cortex and bone defects in the parietal bones bilaterally, as well as in the left occipital bone. …

    Clinical Pediatric Endocrinology 30(1), 71-73, 2021

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  • Direct reduction and repair of spondylolysis with grade 1 slip using the smiley face rod: a case report

    Okuwaki Shun , Tatsumura Masaki , Gamada Hisanori , Ogawa Takeshi , Mammoto Takeo , Hirano Atsushi , Yamazaki Masashi

    … The patient wore a brace for 3 months postoperatively, and partial bone fusion was noted 6 months postoperatively. … He resumed his sports activity 8 months postoperatively, and absolute bone fusion was confirmed 18 months postoperatively. … Grade 1 slip was corrected with absolute bone fusion, and long-term follow-up revealed good results in terms of healing and rehabilitation.</p><p><b>Conclusion:</b> …

    Journal of Rural Medicine 16(1), 56-61, 2021

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  • Spontaneous chondrosarcoma in Wistar rat: a case report

    BALANI Seema , MULLA Mohmad Sadik , SUBRAMANIAN Vijayakumar , JOSE Jomy , BHATNAGAR Upendra

    … Microscopic examinations revealed a large, highly proliferative, noncapsulated growth of chondrocytic or chondroblastic origin in the femoral bone, with proliferating chondrocytes invading the bone and surrounding tissues in an infiltrative growth pattern. …

    Journal of Toxicologic Pathology, 2021

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  • Fabrication and evaluation of ascorbic acid phosphate-loaded spherical porous hydroxyapatite/octacalcium phosphate granules

    KAMITAKAHARA Masanobu , ISHII Airi , MATSUBARA Hideaki , KAWASHITA Masakazu , FURUYA Maiko , KANETAKA Hiroyasu

    … <p>The spherical porous granules of octacalcium phosphate (OCP) and hydroxyapatite (HA) have the potential for applications in scaffolds for bone regeneration. … These granules possessed the potential for applications in artificial bones to promote bone regeneration.</p> …

    Journal of the Ceramic Society of Japan 129(1), 60-65, 2021

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  • Incidentally Discovered Paget's Disease of Bone

    Takahashi Katsutoshi , Aozaki Yuujirou , Unno Toshiyuki , Ishizuka Hiroaki

    Internal Medicine 60(1), 155-156, 2021

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  • Spastic Paraplegia with Paget's Disease of Bone due to a <i>VCP</i> Gene Mutation

    Nakamura Takumi , Kawarabayashi Takeshi , Koh Kishin , Takiyama Yoshihisa , Ikeda Yoshio , Shoji Mikio

    … We herein report a 50-year-old Japanese woman who presented with slowly progressing spastic paraplegia and a history of Paget's disease of bone (PDB). …

    Internal Medicine 60(1), 141-144, 2021

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  • Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa

    Koda Ryo , Narita Ichiei , Miyazaki Satoru , Iino Noriaki , Sato Yo , Hirano Kenichiro , Sunami Eiji , Kosugi Shinichi , Kanefuji Tsutomu , Ogose Akira

    … <p>A 48-year-old woman with a 9-year-history of anorexia nervosa (AN) was admitted complaining of generalized bone pain. …

    Internal Medicine, 2021

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  • Preparation of Calcium Phosphate-Biodegradable Polymer Composites with Ion-Releasing Ability for Enhancing Bone Formation

    Kawai Akari , Matsubara Takashi , Maeda Hirotaka , Obata Akiko , Kasuga Toshihiro

    … <p>An inorganic-organic composite material, consisting of bioresorbable β-tricalcium phosphate (β-TCP) and a biodegradable polymer, is one of the most important materials for use in artificial bone with good shapability. … In this work, to activate bone-forming cells immediately after being implanted in a living body, the ability to release therapeutic ions, such as Ca<sup>2+</sup>, Mg<sup>2+</sup>, and silicate ions was incorporated in the composite material. …

    MATERIALS TRANSACTIONS 62(1), 118-123, 2021

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  • Aspiration of periodontopathic bacteria due to poor oral hygiene potentially contributes to the aggravation of COVID-19

    Takahashi Yuwa , Watanabe Norihisa , Kamio Noriaki , Kobayashi Ryutaro , Iinuma Toshimitsu , Imai Kenichi

    … Periodontitis, one of the most prevalent diseases worldwide, leads to alveolar bone destruction and subsequent tooth loss, and develops due to pro-inflammatory cytokine production induced by periodontopathic bacteria. …

    Journal of Oral Science 63(1), 1-3, 2021

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  • Morphological characteristics of interalveolar septum and mandible in BMAL1 gene knockout mice

    Koshi Ryosuke , Matsumoto Kunihito , Imanishi Yusuke , Kawato Takayuki , Sato Shuichi , Shimba Shigeki , Arai Yoshinori , Honda Kazuya

    … Circadian rhythm is associated with the pathogenesis of systemic disease and bone mineral metabolism. … The mean depth from the cementoenamel junction to the alveolar ridge (virtual bone sounding: VBS) of the interalveolar septum between the first and second molars, and the bone mineral density (BMD) of the interalveolar septum and the mandibular inferior cortex region were calculated. …

    Journal of Oral Science 63(1), 83-86, 2021

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  • Average rate of ridge resorption in denture treatment: A Systematic Review

    Pham Nguyen Quan , Gonda Tomoya , Maeda Yoshinobu , Ikebe Kazunori

    … Body mass index, number of dentures used, denture wearing habit, impression technique, artificial tooth material, and peri-implant bone resorption showed no significant effect on the rate of PRRR. …

    Journal of Prosthodontic Research, 2021

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