Search Results 1-20 of 3123

  • COPD and pulmonary fibrosis  [in Japanese]

    宮本 篤

    呼吸器内科 = Respiratory medicine 39(4), 286-293, 2021-04

  • Homology-Based Image Processing for Automatic Classification of Histopathological Images of Lung Tissue

    Nishio Mizuho , Nishio Mari , Jimbo Naoe , Nakane Kazuaki

    … The private dataset consists of 94 histopathological images that were obtained for the following five categories: normal, emphysema, atypical adenomatous hyperplasia, lepidic pattern of adenocarcinoma, and invasive adenocarcinoma. …

    Cancers 13(6), 1192, 2021-03

    IR 

  • Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD

    Tanabe Naoya , Sato Susumu , Tanimura Kazuya , Oguma Tsuyoshi , Sato Atsuyasu , Muro Shigeo , Hirai Toyohiro

    … This longitudinal 10-year observational study (n=247) showed that the emphysema severity on CT is more closely associated with the progression of airflow limitation and that a reduction in the cross-sectional area of erector spinae muscles (ESMCSA) on CT is more closely associated with mortality than the other CT indices, independent of patient demographics and pulmonary function. … ESMCSA is a useful CT index that is more closely associated with long-term mortality than emphysema and airway disease in patients with COPD. …

    Thorax 76(3), 295-297, 2021-03

    IR 

  • Differentiation of basophils and basophil-mediated type 2 inflammation  [in Japanese]

    三宅 健介 , 吉川 宗一郎 , 柴田 翔 , 烏山 一

    血液内科 = Hematology 82(1), 54-61, 2021-01

  • Two Patients Requiring Unexpected Tracheotomies during Oral Endoscopic Surgery for Pharyngeal Cancer  [in Japanese]

    阪井 茉有子 , 竹浪 民江 , 安藤 寿恵 , 加納 孝一 , 堅田 親利 , 清野 由輩 , 山下 敦 , 岡本 浩嗣

    麻酔 = The Japanese journal of anesthesiology : 日本麻酔科学会準機関誌 70(1), 81-83, 2021-01

  • A case of subcutaneous and mediastinal emphysema due to laceration of the pharyngeal mucosa with an endotracheal tube  [in Japanese]

    TAKAKURA Hiroaki , YAMAMOTO Daisuke , MESE Hiroshi

    … <p>We report a case of subcutaneous and mediastinal emphysema due to laceration of the pharyngeal mucosa with an endotracheal tube.</p><p> … There were no problems in the course up to the second postoperative day, however on the third postoperative day, subcutaneous/mediastinal emphysema appeared in the neck. … An X-ray and CT scan showed extensive subcutaneous/mediastinal emphysema. …

    Japanese Journal of Oral and Maxillofacial Surgery 67(2), 88-94, 2021

    J-STAGE 

  • A Case of Diffuse Pulmonary Ossification with Connective Tissue Weakness Potentially Due to Vascular Ehlers-Danlos Syndrome

    Yoshizumi Yuko , Tomioka Hiromi , Katsuyama Eiji , Kawabata Yoshinori

    … A surgical lung biopsy histology revealed diffuse pulmonary ossification complicated with lung laceration, vascular disruption, hemosiderosis, and emphysema, suggesting vascular Ehlers-Danlos syndrome (vEDS). …

    Internal Medicine, 2021

    J-STAGE 

  • A case of pharyngeal injury by toothbrush with extensive deep cervical and mediastinal emphysema  [in Japanese]

    Minagawa Yui , Omori Tae , Osaka Kei , Yoshihashi Tomokuni , Hirai Seiko , Tamaki Hisamitsu , Misawa Masahiro

    <p>歯ブラシによる咽頭損傷により,重篤な縦隔気腫をもたらした1例を経験した.症例は2歳2か月男児.歯ブラシを咥えて転倒した.歯ブラシの破損はなかった.翌日から発熱と下顎部腫脹を認め近医受診.咽頭粘膜欠損なく,当院耳鼻科へ精査目的で紹介受診.喉頭ファイバーでも穿孔所見なく,熱源精査目的で当科受診となった.室内気で経皮的酸素飽和度(percutaneous oxygen saturati …

    Journal of Japanese Society of Pediatric Radiology 37(1), 101-105, 2021

    J-STAGE 

  • Multi-Institutional Prospective Cohort Study of Patients With Pulmonary Hypertension Associated With Respiratory Diseases

    Tanabe Nobuhiro , Nishimura Yoshihiro , Kimura Hiroshi , Inoue Yoshikazu , Morio Yoshiteru , Nakatsumi Yasuto , Satoh Toru , Hanaoka Masayuki , Kusaka Kei , Sumitani Mitsuhiro , Handa Tomohiro , Kumamaru Hiraku , Sakao Seiicihiro , Kimura Tomoki , Kondoh Yasuhiro , Nakayama Kazuhiko , Tanaka Kensuke , Ohira Hiroshi , Nishimura Masaharu , Miyata Hiroaki , Tatsumi Koichiro , for the JRPHS Group , Tamura Yuichi , Taniguchi Hiroyuki , Emoto Noriaki , Yamada Yoshihito , Nishiyama Osamu , Tsujino Ichizo , Kuraishi Hiroshi

    … study of patients with R-PH to examine real-world characteristics of responders by evaluating demographics, treatment backgrounds, and prognosis.</p><p><b><i>Methods and Results:</i></b>Among the 281 patients with R-PH included in this study, there was a treatment-naïve cohort of 183 patients with normal pulmonary arterial wedge pressure and 1 of 4 major diseases (chronic obstructive pulmonary diseases, interstitial pneumonia [IP], IP with connective tissue disease, or combined pulmonary fibrosis with emphysema); …

    Circulation Journal 85(4), 333-342, 2021

    J-STAGE 

  • Gas-Producing Infection After Initial Unproblematic Treatment of Zygomatic Bone Fracture:A Case Report  [in Japanese]

    KAWABATA Yuya , MORIYAMA Soh , MAKINO Yohjiroh , MIYAWAKI Takeshi

    … CT demonstrated gas emphysema under the right buccal region and maxillary sinus, which suggested postoperative infection. …

    Journal of the Japan Society of Cranio-Maxillo-Facial Surgery 37(1), 27-32, 2021

    J-STAGE 

  • Indium concentration in serum is an excellent predictor for assessing accumulated indium concentration in the lungs

    Hirata Miyuki , Nakano Makiko , Tanaka Akiyo , Omae Kazuyuki

    … Another 1 Japanese case (Case 6) exposed to indium trioxide and indium hydroxide was referred from an article.</p><p><b>Results</b>: Cases 1 and 3 had lung cancer, Case 2 suffered from recurrent pneumothorax, and Case 4 had interstitial pneumonia with mild emphysema. … Case 5 had severe emphysema with pulmonary hypertension and underwent bilateral lung transplantation. …

    Journal of Occupational Health 63(1), n/a, 2021

    J-STAGE 

  • A CASE OF BILATERAL ESOPHAGEAL PERFORATION CAUSED BY CHICKEN BONE THAT WAS EXTRACTED VIA ENDOSCOPY WITHOUT SURGERY  [in Japanese]

    YONEZAWA Emi , TAKENO Shinsuke , KAWAKAMI Hiroshi , MIIKE Tadashi , SAKAMOTO Kazuki , NODA Takaho , SUZUKI Sho , YAMAMOTO Shojiro , KAWANO Fumiaki , NANASHIMA Atsushi

    <p>症例は40歳,男性.夕食時に鶏の丸焼きを摂取後,前胸部痛を認めた.CTで胸部下部食道に4cm長の線状の高吸収域を指摘され,周囲には縦隔気腫も併発していた.鶏骨による食道穿孔が疑われ,当科紹介受診.外科のバックアップの下,上部消化管内視鏡による異物摘出を試みたところ,胸部下部食道の左右両側壁に穿孔する鶏骨と思われる異物を認めた.把持鉗子を用いて下行大動脈に近接する左側から抜去し,先 …

    GASTROENTEROLOGICAL ENDOSCOPY 63(1), 31-37, 2021

    J-STAGE 

  • Management of air leak after surgery for primary lung cancer  [in Japanese]

    Tempaku Hironori , Fujinaga Kazuya

    <p>原発性肺癌術後の気漏に対し治療を施行した46例(喫煙者37例,肺気腫合併28例)の管理方法を検討した.術式は二葉切除3例,肺葉切除38例,区域切除4例,部分切除1例(胸腔鏡下手術31例).5例に術後3.2±2.6日で再手術を施行.43例(再手術後も気漏が残存した2例を含む)に術後5.3±2.5日で癒着療法(OK-432:25例,minocycline:17例,50%ブドウ糖液:1 …

    The Journal of the Japanese Association for Chest Surgery 35(1), 12-17, 2021

    J-STAGE 

  • Syndrome of inappropriate secretion of antidiuretic hormones possibly caused by insufficient chest drainage for refractory secondary pneumothorax: A case report  [in Japanese]

    Harada Hiroaki , Fujiwara Makoto , Shibata Satoshi

    <p>症例は66歳男性.気胸の治療歴がある重症COPDで在宅酸素療法中に右気胸を生じ救急搬送された.胸腔ドレナージを行いOK432による胸腔内癒着療法で一旦軽快するも,入院経過観察中に気胸の再発を繰り返した.高度肺気腫であることなどから手術療法は行わず繰り返しの癒着療法および自己血注入にて対処したが,徐々に胸腔内は部分的な癒着を生じていった.入院経過観察中に再度気胸を発症し胸腔ドレナー …

    The Journal of the Japanese Association for Chest Surgery 35(1), 32-36, 2021

    J-STAGE 

  • Thymus and activation-regulated chemokine (TARC/CCL17) predicts decline of pulmonary function in patients with chronic obstructive pulmonary disease

    Machida Hiroyoshi , Sato Masamichi , Nemoto Takako , Sato Chisa , Nishiwaki Michiko , Yamauchi Keiko , Igarashi Akira , Tokairin Yoshikane , Watanabe Masafumi , Inoue Sumito , Shibata Yoko , Kimura Tomomi , Sato Kento , Abe Koya , Murano Hiroaki , Yang Sujeong , Nakano Hiroshi

    … In the FEV<sub>1</sub>-rapid-decline group, the frequency of exacerbations, the degree of emphysema, and serum levels of TARC was higher than in the non-rapid-decline group. … as a classifier instead of FEV<sub>1</sub>, age, the frequency of exacerbations, the degree of emphysema and serum levels of TARC in the rapid-decline group was significantly greater than those in the non-rapid-decline group. …

    Allergology International 70(1), 81-88, 2021

    J-STAGE 

  • Idiopathic Pulmonary Hemosiderosis Associated with Emphysematous Change in an Adult Who Underwent Lung Transplantation

    Gocho Kyoko , Sato Kenya , Imasaka Keisuke , Hamanaka Nobuyuki , Takahashi Miki , Shimizu Kunihiko , Takemura Tamiko

    … A surgical lung biopsy revealed peribronchial hemosiderosis, centrilobular emphysema, and fragile elastic fibers of the alveolar septa and small vessels. …

    Internal Medicine 60(1), 117-122, 2021

    J-STAGE 

  • The Japanese Herbal (Kampo) Medicine Hochuekkito Attenuates Lung Inflammation in Lung Emphysema

    Isago Hideaki , Matsuzaki Hirotaka , Yatomi Yutaka , Nagase Takahide , Jo Taisuke , Mitani Akihisa , Kohno Shiho , Nagoshi Saki , Ishimori Taro , Saito Minako , Tamiya Hiroyuki , Miyashita Naoya , Ishii Takashi

    … using a mouse model of lung emphysema. … CKO mice) as the lung emphysema model mimicking the chronic pulmonary inflammation in COPD. … These results suggest that TJ-41 has anti-inflammatory effects in lung emphysema both in the chronic phase and during an acute exacerbation. … In conclusion, our study sheds light on the anti-inflammatory effects of TJ-41 in lung emphysema. …

    Biological and Pharmaceutical Bulletin 44(1), 39-45, 2021

    J-STAGE 

  • Central airway and peripheral lung structures in airway disease dominant COPD  [in Japanese]

    Tanabe Naoya , Shimizu Kaoruko , Terada Kunihiko , Sato Susumu , Suzuki Masaru , Shima Hiroshi , Oguma Akira , Oguma Tsuyoshi , Konno Satoshi , Nishimura Masaharu , Hirai Toyohiro

    … This study aimed to examine whether the computed tomography (CT)-based airway disease-dominant (AD) subtype, defined using the central airway dimension, was less associated with small airway dysfunction (SAD) on CT, compared to the emphysema-dominant (ED) subtype. …

    ERJ Open Research, 2021

    IR 

  • Pathology of Idiopathic Pulmonary Fibrosis Assessed by a Combination of Microcomputed Tomography, Histology, and Immunohistochemistry

    Tanabe Naoya , McDonough John E. , Vasilescu Dragoş M. , Ikezoe Kohei , Verleden Stijn E. , Xu Feng , Wuyts Wim A. , Vanaudenaerde Bart M. , Colby Thomas V. , Hogg James C.

    … An experienced pathologist scored 3 major UIP criteria (patchy fibrosis, honeycomb, and fibroblastic foci), 5 additional pathological changes such as emphysema, and immunohistochemical staining for CD68, CD4, CD8, and CD79a positive cells, graded on a 0-3+ scale. …

    The American Journal of Pathology 190(12), 2427-2435, 2020-12

    IR 

  • Ninjin'yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression

    Miyamoto Atsushi , Asai Kazuhisa , Kadotani Hideaki , Maruyama Naomi , Kubo Hiroaki , Okamoto Atsuko , Sato Kanako , Yamada Kazuhiro , Ijiri Naoki , Watanabe Tetsuya , Kawaguchi Tomoya

    研究グループは、病後や術後の食欲不振に処方される漢方薬「人参養栄湯」がCOPD(慢性閉塞性肺疾患)の骨格筋合併症に効果があることを明らかにしました。加齢や疾患により筋力が衰え、疲れやすくなり家に閉じこもりがちになるなど、健常から要介護へ移行する中間の段階である衰え全般を「フレイル」と呼び、健康寿命増進のための課題として注目されています。COPDは主にタバコ煙を吸入することにより肺胞が破壊されたり気 …

    International Journal of Chronic Obstructive Pulmonary Disease 2020(15), 3063-3077, 2020-11-27

    IR 

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