CiNii Articles - glymphatic system

1

Aging of the Vascular System and Neural Diseases.

WATANABE Chisato , IMAIZUMI Tsutomu , KAWAI Hiromi , SUDA Kazuma , HONMA Yoichi , ICHIHASHI Masamitsu , EMA Masatsugu , MIZUTANI Ken-Ichi , 渡部千里 , 依馬正次

… Furthermore, the glymphatic system and meningeal lymphatic systems contribute to a functional unit for clearance of amyloid β from the brain from the central nervous system into the cervical lymph nodes. … This review article will also focus on recent advances in stem cell therapies that aim at repopulation or regeneration of a degenerating vascular system for neural diseases. …

Frontiers in Aging Neuroscience (12), 2020-09-29

IR
2

Importance of sleep disorders in the internal medicine [in Japanese]

平田幸一

日本内科学会雑誌 109(9), 1708-1719, 2020-09-10

Ichushi Web
3

招請講演内科疾患における睡眠障害の重要性 (第117回日本内科学会講演会(2020年) 革新と伝統が協奏する内科学) [in Japanese]

平田幸一

日本内科学会雑誌 109(臨増), 98-103,142, 2020-02-26

Ichushi Web
4

Glymphatic imaging using MRI

Taoka Toshiaki , Naganawa Shinji

… In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid (CSF) or interstitial fluid (ISF) has been suggested by many studies. … The glymphatic system is hypothesized to be a waste clearance system of the CSF through the perivascular and interstitial spaces in the brain. …

Journal of Magnetic Resonance Imaging 51(1), 11-24, 2020-01

IR
5

Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent

Naganawa Shinji , Ito Rintaro , Kawai Hisashi , Taoka Toshiaki , Yoshida Tadao , Sone Michihiko

Purpose: It has been reported previously that intravenously administered gadolinium-based contrast agent (GBCA) leaks into the subarachnoid space around the cortical veins at 4 h after inject …

Magnetic Resonance in Medical Sciences 19(4), 375-381, 2020

J-STAGE
6

The Glymphatic System: A Review of the Challenges in Visualizing its Structure and Function with MR Imaging

Naganawa Shinji , Taoka Toshiaki

… The central nervous system (CNS) was previously thought to be the only organ system lacking lymphatic vessels to remove waste products from the interstitial space. … Recently, based on the results from animal experiments, the glymphatic system was hypothesized. … It has been reported that the glymphatic system is particularly active during sleep. …

Magnetic Resonance in Medical Sciences, 2020

J-STAGE
7

Relationship between Parasagittal Perivenous Cysts and Leakage of Gadolinium-based Contrast Agents into the Subarachnoid Space around the Cortical Veins after Intravenous Administration

Naganawa Shinji , Ito Rintaro , Nakamichi Rei , Kawamura Mariko , Kawai Hisashi , Taoka Toshiaki , Yoshida Tadao , Sone Michihiko

Purpose: The purpose of this retrospective study was to investigate the relationship between the number and size of cystic structures around the cortical veins near the superior sagittal sinu …

Magnetic Resonance in Medical Sciences, 2020

J-STAGE
8

Intracranial Distribution of Intravenously Administered Gadolinium-based Contrast Agent over a Period of 24 Hours: Evaluation with 3D-real IR Imaging and MR Fingerprinting

Naganawa Shinji , Pfeuffer Josef , Nittka Mathias , Sone Michihiko , Ito Rintaro , Kato Yutaka , Kawai Hisashi , Taoka Toshiaki , Yoshida Tadao , Maruyama Katsuya , Murata Katsutoshi , Körzdörfer Gregor

Purpose: To evaluate the feasibility for the detection of slight contrast effects after intravenous administration of single dose gadolinium-based contrast agent (IV-SD-GBCA), the time course …

Magnetic Resonance in Medical Sciences, 2020

J-STAGE
9

Involvement of glymphatic system in amyotrophic lateral sclerosis pathology [in Japanese]

Mikako Hirose , Asano Mito , Shitara Shusei , Abe Yoichiro , Yasui Masato , Tokuda Eiichi , Furukawa Yoshiaki , Misawa Hidemi

… The glymphatic system is a waste clearance system in the central nervous system: the directional flow of the cerebrospinal fluid (CSF) through the perivascular into interstitial spaces and the perivascular localization of aquaporin-4 (AQP4) promote its directional flow. …

Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-YIA-32, 2020

J-STAGE
10

The Spatial Distribution of Water Components with Similar T2 May Provide Insight into Pathways for Large Molecule Transportation in the Brain

Oshio Koichi , Yui Masao , Shimizu Seiko , Yamada Shinya

… Purpose: Although there is no lymphatic system in the central nervous system (CNS), there seems to be a mechanism to remove macro molecules from the brain. … component analysis it is possible to obtain some insight into pathways for the transport of large molecules in the CNS, where no lymphatic system is present. …

Magnetic Resonance in Medical Sciences, 2020

J-STAGE
11

The Space between the Pial Sheath and the Cortical Venous Wall May Connect to the Meningeal Lymphatics

Naganawa Shinji , Ito Rintaro , Taoka Toshiaki , Yoshida Tadao , Sone Michihiko

… This new anatomical concept regarding the outflow from the glymphatic system might be important for the future research in neuroscience. …

Magnetic Resonance in Medical Sciences 19(1), 1-4, 2020

J-STAGE
12

Choroid plexus and mental disorders [in Japanese]

今村聖路 , 内匠透

精神科 = Psychiatry 35(4), 362-368, 2019-10
13

Anatomical structure and physiological functions of the perivascular and paravascular spaces in vivo [in Japanese]

石川智愛

医学のあゆみ 270(13), 1210-1213, 2019-09-28

Ichushi Web
14

Anatomically based cerebrospinal fluid dynamics : A relations with the meningeal-extravascular fluid pathways and CSF lymph absorptive routs for cerebrospinal fluid [in Japanese]

三浦真弘 , 山田茂樹

医学のあゆみ 270(13), 1203-1209, 2019-09-28

Ichushi Web
15

Cerebral spinal fluid turnover and the glymphatic system [in Japanese]

平瀬肇

医学のあゆみ 270(13), 1199-1201, 2019-09-28

Ichushi Web
16

Mechanism of brain lymphatic drainage [in Japanese]

木多眞也

医学のあゆみ 270(13), 1193-1198, 2019-09-28

Ichushi Web
17

Glymphatic system and MR imaging [in Japanese]

長縄慎二

医学のあゆみ 270(13), 1189-1192, 2019-09-28

Ichushi Web
18

The elimination system of the brain, and diseases caused by its failure [in Japanese]

山岸拓磨 , 小野寺理

医学のあゆみ 270(13), 1183-1187, 2019-09-28

Ichushi Web
19

Rules of aquaporin4 in waste clearance system of brain [in Japanese]

五十嵐博中

Dementia Japan : 日本認知症学会誌 33(3), 270-277, 2019-09
20

Small vessel disease and Alzheimer's disease ; the glymphatic pathway in amyloid beta clearance system [in Japanese]

Shindo Akihiro

… There are two major type of clearance system through cerebrospinal fluid (CSF) and interstitial fluid (ISF), which are divided into perivascular drainage pathway and glymphatic pathway. … Recently, the glymphatic pathway has been noted, and further implicated that the glymphatic function can be related pathologically to Alzheimer's disease. …

Neurological Therapeutics 36(4), 524-527, 2019

J-STAGE Ichushi Web

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