Search Results 1-20 of 1047

  • The course of illness and difficulty of care for a patient with amyotrophic lateral sclerosis and Huntington's disease  [in Japanese]

    Ushikubo Mitsuko , Kushiya Masako , Takahashi Chisato

    本研究は、筋萎側索硬化症(ALS)とハンチントン病(HD)の2つの神経難病をかかえた療養者の療養経過とケア困難を明らかにした。対象事例A氏(60歳台)の妻と訪問看護師の2名を対象者として半構成的面接を行った。療養経過は、201X年にALSの診断、その後すぐにHDの診断を受けた。診断から死亡までの期間は9か月であった。妻と訪問看護師のとらえたA氏の心境として、【病気のショックとしょうがない気持ち】、 …

    Ann Gunma Health Sci 40(0), 36-41, 2020

    J-STAGE 

  • Selection indices for non-wilted silage preparation in timothy(<i>Phleum pratense</i> L.)  [in Japanese]

    ASHIKAGA Kazunori , OKAMOTO Hideki , TANAKA Tsuneki

    <p>無予乾サイレージ調製に適するチモシーの選抜指標を明らかにするため、8栄養系を用いて検討した。その結果、発酵品質の指標(pH、揮発性塩基態窒素(VBN) / 全窒素(TN)、V-SCORE、フリーク評点)の広義の遺伝率は、VBN / TNを除きいずれも高く、育種改良の可能性が示唆された。収穫時の乾物率、可溶性炭水化物(WSC)含量、低消化性繊維(Ob)含量について、大半の発酵品質指 …

    Hokkaido Journal of Livestock and Grassland Science 8(1), 13-20, 2020

    J-STAGE 

  • Effectiveness of body measurement traits for improving production traits in Duroc pigs  [in Japanese]

    YAZAKI Natsumi , OGAWA Shinichiro , OHNISHI Chika , ISHII Kazuo , UEMOTO Yoshinobu , SATOH Masahiro

    <p>デュロック種2,835頭の記録を用いて,体型形質(体長,体高,前幅,胸幅,後幅,胸深,胸囲,前肢および後肢管囲,前肢および後肢つなぎ,ボディマス指数,体密度)および産肉形質(検定開始時および検定終了時日齢,一日平均増体重(DG),背脂肪厚(BF),ロース芯面積(LMA)および筋肉内脂肪含量(IMF))の遺伝的パラメーターを推定した.体型形質の遺伝率は後幅の0.24から後肢管囲の0 …

    Nihon Chikusan Gakkaiho 91(1), 9-16, 2020

    J-STAGE 

  • Current status and prospects of common buckwheat breeding in Japan

    Ohsawa Ryo

    … Because the main breeding method used for common buckwheat is mass selection, the merits and demerits of this method are explored from the perspective of heritability. …

    Breeding Science 70(1), 3-12, 2020

    J-STAGE 

  • Vision for the future genomic research in dementia  [in Japanese]

    宮川 統爾 , 岩田 淳

    老年精神医学雑誌 30(11), 1201-1207, 2019-11

    Ichushi Web 

  • Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population

    Otsuka Ikuo , Akiyama Masato , Shirakawa Osamu , Okazaki Satoshi , Momozawa Yukihide , Kamatani Yoichiro , Izumi Takeshi , Numata Shusuke , Takahashi Motonori , Boku Shuken , Sora Ichiro , Yamamoto Ken , Ueno Yasuhiro , Toga Tatsushi , Kubo Michiaki , Hishimoto Akitoyo

    … Twin, family, and adoption studies have suggested high heritability for suicide, but genetics lags behind due to difficulty in obtaining samples from individuals who died by suicide, especially in non-European populations. … Although we identified no genome-wide significant single-nucleotide polymorphisms (SNPs), we demonstrated significant SNP-based heritability (35-48%; …

    Neuropsychopharmacology 44(12), 2119-2124, 2019-11

    IR 

  • Testing the Adaptive Potential of Yellowtail Kingfish to Ocean Warming and Acidification

    Philip L. Munday , Celia Schunter , Bridie J. M. Allan , Simon Nicol , Darren M. Parsons , Stephen M. J. Pether , Stephen Pope , Timothy Ravasi , Alvin N. Setiawan , Neville Smith , Jose A. Domingos

    … Estimating the heritability and genotype by environment (GxE) interactions of performance-related traits (e.g., growth, survival, reproduction) under future ocean conditions is necessary for inferring the adaptive potential of marine species to climate change. … We used an experimental approach to test for heritability and GxE interactions in morphological traits of juvenile yellowtail kingfish, Seriola lalandi, under current-day and predicted future ocean conditions. …

    Frontiers in Ecology and Evolution (7), 253, 2019-07-09

    IR 

  • Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea

    大澤 良 , 江面 浩 , Takahiro Tsusaka , Bunsho Makino , Ryo OHSAWA , Hiroshi EZURA

    … Broad sense heritability of β-eudesmol, hinesol, atractylon, and atractylodin contents were 0.84, 0.77, 0.86, and 0.87, respectively. …

    PLOS ONE 14(5), e0217522, 2019-05

    IR 

  • Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines

    山岸 良匡 , Yoshihiro Kokubo , Sandosh Padmanabhan , Yoshio Iwashima , Kazumasa YAMAGISHI , Atsushi Goto

    … Family history and twin studies have yielded heritability estimates of BP in the range of 34–67%. … An overestimation of heritability may have occurred in twin studies due to violations of shared environment assumptions, poor phenotyping practices in control cohorts, failure to account for epistasis, gene-gene and gene-environment interactions, and other non-genetic sources of phenotype modulation that are suspected to lead to underestimations of heritability in GWAS. …

    Environmental health and preventive medicine (24), 19, 2019-03

    IR 

  • Genetics of clinical measurements in the Japanese population : large-scale genome-wide association study of 58 quantitative traits  [in Japanese]

    金井 仁弘 , 岡田 随象 , 鎌谷 洋一郎

    臨床免疫・アレルギー科 = Clinical immunology & allergology 71(1), 78-85, 2019-01

  • Identification of 12 novel loci that confer susceptibility to early-onset dyslipidemia

    佐久間 淳 , Yoshiji Yamada , Kimihiko Kato , Mitsutoshi Oguri , Hideki Horibe , Tetsuo Fujimaki , Yoshiki Yasukochi , Ichiro Takeuchi , Jun SAKUMA

    … The circulating concentrations of triglycerides, high density lipoprotein (HDL)‑cholesterol, and low density lipoprotein (LDL)‑cholesterol have a substantial genetic component, and the heritability of early‑onset dyslipidemia might be expected to be higher compared with late‑onset forms. …

    International journal of molecular medicine 43(1), 57-82, 2019-01

    IR 

  • Exploring biomarkers and therapeutic targets by genome copy number variation  [in Japanese]

    Nagai Taku , Ozaki Norio , Yamada Kiyofumi

    … <p>Research on human genetics of schizophrenia enables to discover effective targets for its diagnosis and medication because of its high heritability. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 92(0), 2-S15-3, 2019

    J-STAGE 

  • Selection Method for Competitive Ability of Timothy (<i>Phleum pratense</i> L.) against Rhizomatous Grass Weeds under Field Conditions:1. Method to evaluate competitive ability under weedy conditions  [in Japanese]

    Ashikaga Kazunori , Deguchi Kenzaburo

    <p>チモシーのシバムギ(QG)およびリードカナリーグラス(RCG)に対する競合力の栄養系間差異と評価方法について,両雑草との混植下においてチモシーの20栄養系を用いて検討した。その結果,乾物重について大半の収穫時において有意な栄養系間差異と中程度から高い広義の遺伝率が認められ,育種改良の可能性が示唆された。また,本競合力の指標である2か年合計乾物重は両雑草競合条件間で強い遺伝相関を示 …

    Japanese Journal of Grassland Science 65(3), 167-172, 2019

    J-STAGE 

  • A study on the potential for improving number born alive using teat number in pig female breeds  [in Japanese]

    KONTA Ayane , OGAWA Shinichiro , KIMATA Makoto , ISHII Kazuo , UEMOTO Yoshinobu , SATOH Masahiro

    <p>乳頭数を選抜指標としたブタの生存産子数における改良の可能性を検討するため,雌系純粋種豚の乳頭数および生存産子数における遺伝的パラメーターを推定した.ランドレース種および大ヨークシャー種における正常乳頭数の記録(それぞれ20,405頭および17,738頭),生存産子数の記録(64,810件および51,798件)および血統記録(79,224頭および68,615頭)を用いた.正常乳頭数 …

    Nihon Chikusan Gakkaiho 90(3), 207-212, 2019

    J-STAGE  JASI  Ichushi Web 

  • Evaluation of combining ability for pine wood nematode-resistance based on half-diallele lines of <i>Pinus densiflora</i> resistant clones  [in Japanese]

    Iwaizumi Masakazu G. , Tamaki Satoshi , Isoda Keiya , Kubota Masahiro

    <p>アカマツの次世代抵抗性育種を効果的に推進する上では、数ある第一世代からの交配親の選定基準や抵抗性の遺伝性等について検討する必要がある。本研究では、36系統のマツノザイセンチュウ抵抗性アカマツを用いた9セットの4×4ハーフダイアレル交配家系を対象として、抵抗性の遺伝試験を実施した。線虫接種後の交配家系の生存率は6箇所の試験地間や各試験地内の反復間で大きく異なったが、交配組合せ間でも …

    Forest Genetics and Tree Breeding 8(3), 121-130, 2019

    J-STAGE 

  • Genomic selection on shelling percentage and other traits for maize

    Sun Qi , Wang Ping , Li Wenlan , Li Wencai , Lu Shouping , Yu Yanli , Zhao Meng , Meng Zhaodong

    … The Higher trait heritability resulted in better prediction efficiency; …

    Breeding Science 69(2), 266-271, 2019

    J-STAGE 

  • Synaptic functions and their disruption in schizophrenia: From clinical evidence to synaptic optogenetics in an animal model

    OBI-NAGATA Kisho , TEMMA Yusuke , HAYASHI-TAKAGI Akiko

    … We will focus on schizophrenia, because this condition has a high proven heritability, which offers more unambiguous insights into the biological origins of not only schizophrenia but also related psychiatric disorders. …

    Proceedings of the Japan Academy, Series B 95(5), 179-197, 2019

    J-STAGE 

  • Inheritance of susceptibility to bacterial spot (<i>Xanthomonas arboricola</i> pv. <i>pruni</i>) in peach offspring populations derived from Brazilian and Japanese cultivars/selections

    Suesada Yuko , Yamada Masahiko , Sawamura Yutaka , Adachi Eisuke , Yaegaki Hideaki , Yamaguchi Masami , Yamamoto Toshiya

    <p>Bacterial spot (caused by <i>Xanthomonas arboricola</i> pv. <i>pruni</i>) is a serious disease and difficult to control in peach cultivation, and inheritance manner of …

    Breeding Science 69(1), 11-18, 2019

    J-STAGE 

  • Transgenerational transmission of schizophrenia risk  [in Japanese]

    有波 忠雄

    精神科 = Psychiatry 33(4), 295-299, 2018-10

    Ichushi Web 

  • Genetic influences on prefrontal activation during a verbal fluency task in children: A twin study using near-infrared spectroscopy

    Sakakibara Eisuke , Takizawa Ryu , Kawakubo Yuki , Kuwabara Hitoshi , Kono Toshiaki , Hamada Kasumi , Okuhata Shiho , Eguchi Satoshi , Ishii-Takahashi Ayaka , Kasai Kiyoto

    … Classical structured equation modeling was used to estimate the heritability. …

    Brain and Behavior 8(6), 2018-06

    IR 

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