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  • Gamma-Aminobutyric Acid (GABA) Attenuates Ischemia Reperfusion-Induced Alterations in Intestinal Immunity

    Kubota Atsuhito , Kobayashi Masaki , Sarashina Sota , Takeno Reiko , Yasuda Genki , Narumi Katsuya , Furugen Ayako , Takahashi-Suzuki Natsuko , Iseki Ken

    … and to determine the effect of GABA on intestinal ischemia reperfusion (I/R) injury-induced intestinal innate immunity. … Intestinal I/R was induced by a 30-min occlusion of the superior mesenteric artery followed by a reperfusion for 60-min. This led to a significant decrease in IgA secretion, and mRNA levels of RD-5 and Sod 1-3 in the ileum. …

    Biological and Pharmaceutical Bulletin 41(12), 1874-1878, 2018

    J-STAGE  Ichushi Web 

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