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  • A CxxC Domain That Binds to Unmethylated CpG Is Required for KDM2A to Control rDNA Transcription  [in Japanese]

    Tsuneoka Makoto , Tanaka Yuji , Okamoto Kengo

    … We had reported that histone demethylase KDM2A reduced ribosomal RNA transcription in response to starvation. … In this symposium, we reported our recent results showing the mechanism by which KDM2A was recruited to rDNA chromatin. … We found that KDM2A bound to a rDNA promoter with unmethylated CpG dinucleotides <i>via</i> … KDM2A CxxC-zinc finger motif. …

    YAKUGAKU ZASSHI 135(1), 11-21, 2015

    J-STAGE  Ichushi Web 

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