Search Results 1-20 of 9983

  • The role of vitamin and mineral on mitochondrial energy metabolism  [in Japanese]

    伊美 友紀子 , 吉岡 泰淳 , 川畑 球一 , 寺尾 純二 , 柴田 克己

    甲南女子大学研究紀要. II = Konan Women's University studies. II (15), 49-56, 2021-03-18

    IR 

  • Mitochondrial movement during its association with chloroplasts in Arabidopsis thaliana

    Oikawa Kazusato , Imai Takuto , Thagun Chonprakun , Toyooka Kiminori , Yoshizumi Takeshi , Ishikawa Kazuya , Kodama Yutaka , Numata Keiji

    葉緑体との相互作用におけるミトコンドリア運動を発見 --相互作用の制御による効率的な物質代謝の可能性に期待--. 京都大学プレスリリース. 2021-03-19.

    Communications Biology (4), 2021-03-05

    IR 

  • Differences in the Central Energy Metabolism of Cancer Cells between Conventional 2D and Novel 3D Culture Systems.

    IKARI Ryo , MUKAISHO Ken-ichi , KAGEYAMA Susumu , NAGASAWA Masayuki , KUBOTA Shigehisa , NAKAYAMA Takahisa , MURAKAMI Shoko , TANIURA Naoko , TANAKA Hiroyuki , KUSHIMA Ryoji , KAWAUCHI Akihiro , 伊狩 亮 , 向所 賢一 , 影山 進 , 永澤 誠之 , 窪田 成寿 , 仲山 貴永 , 村上 翔子 , 田中 裕之 , 九嶋 亮治 , 河内 明宏

    … The 3D culture system did not impair mitochondrial function in the cancer cells and produce energy through the mitochondria simultaneously with aerobic glycolysis. …

    International Journal of Molecular Sciences 22(4), 2021-02-11

    IR 

  • An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia

    Morimoto Hiroko , Yamamoto Takuya , Miyazaki Takehiro , Ogonuki Narumi , Ogura Atsuo , Tanaka Takashi , Kanatsu-Shinohara Mito , Yabe-Nishimura Chihiro , Zhang Hongliang , Pommier Yves , Trumpp Andreas , Shinohara Takashi

    酸素による活性酸素制御が精子形成に果たす役割を解明 --活性酸素制御の破綻が男性不妊を引き起こす--. 京都大学プレスリリース. 2021-01-15.

    Genes & Development 35(3-4), 250-260, 2021-02-01

    IR 

  • ATP dynamics in the kidney by in vivo ATP imaging  [in Japanese]

    山本 伸也 , 柳田 素子

    腎臓内科 = Nephrology 13(2), 216-224, 2021-02

  • The regulation of physiological and pathological mechanisms by mitochondrial dynamics  [in Japanese]

    石原 孝也 , 小笠原 絵美 , 石原 直忠

    腎臓内科 = Nephrology 13(2), 238-245, 2021-02

  • The studies of the endosomal protein MLN64 in the cholesterol trafficking to the mitochondria in the human placental cells  [in Japanese]

    奈良 篤樹

    アグリバイオ = Agricultural biotechnology 5(2), 184-189, 2021-02

  • The functionality of food products by natural fermentation of plant-derived microorganisms and microorganisms living in cypress barrels  [in Japanese]

    本藤 和彦 , 馬場 亜沙美 , 原 太一 , 和泉 達也 , 吉田 雄介

    New food industry = ニューフードインダストリー 63(2), 93-152, 2021-02

  • Thermogenesis and energy metabolism in brown adipose tissue  [in Japanese]

    西頭 英起

    臨床免疫・アレルギー科 = Clinical immunology & allergology 75(2), 226-232, 2021-02

  • Astaxanthin Prevents Atrophy in Slow Muscle Fibers by Inhibiting Mitochondrial Reactive Oxygen Species via a Mitochondria-Mediated Apoptosis Pathway

    Sun Luchuanyang , Miyaji Nobuyuki , Yang Min , Mills Edward M. , Taniyama Shigeto , Uchida Takayuki , Nikawa Takeshi , Li Jifeng , Shi Jie , Tachibana Katsuyasu , Hirasaka Katsuya

    … This study aimed to investigate the effects of AX on muscle-atrophy-mediated disturbance of mitochondria, which have a lipid bilayer. … To confirm the AX phenotype in the soleus muscle, we examined its effects on mitochondria using Sol8 myotubes derived from the soleus muscle. … These results suggested that AX protected the functional stability of mitochondria, alleviated mitochondrial oxidative stress and mitochondriamediated apoptosis, and thus, prevented muscle atrophy. …

    Nutrients 13(2), 379, 2021-01-26

    IR 

  • Characterization of Light-Enhanced Respiration in Cyanobacteria

    Shimakawa Ginga , Kohara Ayaka , Miyake Chikahiro

    … It is likely stimulated by an increase in respiratory substrates produced during photosynthetic CO2 assimilation and function in keeping the metabolic and redox homeostasis in the light in eukaryotic cells, based on the interactions among the cytosol, chloroplasts, and mitochondria. …

    International Journal of Molecular Sciences 22(1), 342, 2021-01

    IR 

  • Challenge of Developing Mitochondria-Targeted Nano Medicine Using Crowdfunding  [in Japanese]

    山田 勇磨 , 石神 圭子 , 日比野 はるか

    製剤機械技術学会誌 = Journal of pharmaceutical machinery and engineering 30(1), 20-28, 2021

  • Study on regulation of skeletal muscle characteristics by food components  [in Japanese]

    KOMIYA Yusuke

    <p>骨格筋を構成する筋線維は異なる性質を示す遅筋タイプと速筋タイプに大別される.遅筋タイプはミトコンドリアに富み,酸化能力に長け,抗疲労性を示す.食肉においては遅筋タイプの割合が高まると,テクスチャー改善,機能性成分の増加,呈味性向上などにつながる.これまで後天的な遅筋タイプの増加は運動トレーニングによってのみ生じると考えられていた.我々はオレイン酸を骨格筋細胞に作用させると遅筋タイ …

    Nihon Chikusan Gakkaiho 92(1), 25-33, 2021

    J-STAGE 

  • The Molecular Mechanisms of Mitochondrial Calcium Uptake by Calcium Uniporter  [in Japanese]

    Yamamoto Takenori

    … <p>Mitochondria play a role as intracellular calcium stores as well as energy conversion functions. … Excessive calcium accumulation in mitochondria induces cell death and induces diseases such as ischemia-reperfusion injury. … In the previous study, various subunits of mammalian calcium uniporter were expressed in the yeast mitochondria. …

    YAKUGAKU ZASSHI 141(4), 491-499, 2021

    J-STAGE 

  • Smooth Loop-Like Mitochondrial Nucleus in the Primitive Red Alga <i>Cyanidioschyzon merolae</i> Revealed by Drying Treatment

    Kuroiwa Tsuneyoshi , Kuroiwa Haruko , Yagisawa Fumi , Fujiwara Takayuki , Misumi Osami , Nagata Noriko , Imoto Yuuta , Yoshida Yamato , Mogi Yuko , Miyagishima Shin-ya

    … <p>It is thought that mitochondria were generated by the symbiosis of autonomous α-proteobacteria and a eukaryote-like organism derived from an archaeon of the species <i>Sulfolobus</i>. … The primitive unicellular eukaryote evolved into organisms with one mitochondrion containing multiple mtDNA copies per cell, and organisms with multiple mitochondria with a small number of mtDNA copies in each cell. …

    CYTOLOGIA 86(1), 89-96, 2021

    J-STAGE 

  • CAMKII inhibitor as novel cardioprotective agent ondoxorubicin cardiotoxicity  [in Japanese]

    アグン クルニアワン プリヨノ , Miake Junichiro , Syuu Youkou , Ichihara Katsunori , Sawano Tatsuya , Nagata Keiko , Imamura Takeshi

    … Similarly, DOX-inducedmitophagy was significantly suppressed by KN-93 treatment (mitophagy positivecells: control 58.0 ± 4.0%, DOX 58.0 ± 4.0%, KN-93 group 39.5 ± 8%, P value<0.05, n = 4).</p><p>Conclusion: DOX activates the CamKII and Drp-1 proteins and causes mitochondrialdysfunction due to mitochondrial injury and abnormal division of mitochondria.Molecules involved in the activation of CamKII and its signalling pathway aretarget molecules for the development of prophylactic agents for DOX-inducedcardiotoxicity</p> …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-Y-G2-3, 2021

    J-STAGE 

  • Networks of organelle function in cardiovascular diseases  [in Japanese]

    Zhang Yong

    … Here we studied the regulatory effects of non-coding RNAs on function and crosstalk among cell organelles especially in endoplasmic reticulum (ER) and mitochondria in different CVDs. … In mitochondria, we found mitomiR-4485-3p and lncRNA MIAT impaired myocardial infarction (MI) by inducing cardiomyocytes apoptosis. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-S32-1, 2021

    J-STAGE 

  • Redox regulation of mitochondrial quality as a therapeutic target of cardiac senescence  [in Japanese]

    Nishida Motohiro

    … <p>Mitochondria are dynamic organelles that continuously undergo fission and fusion, which are necessary for maintaining bioenergetic homeostasis and robustness in heart. … Especially, mitochondria predominantly show tubular form in adult cardiomyocytes and are reported to be fragmented by the exposure to electrophilic chemical substances produced by hypoxic and hyperglycemic stress. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-S32-2, 2021

    J-STAGE 

  • Regulation of mitochondrial activities by TRPA1 channel  [in Japanese]

    Hasegawa Yoshiaki , Hamano Satoru , Mori Yasuo , Takahashi Nobuaki

    … NDUFAF4 overexpression allowed TRPA1 to be localized into mitochondria. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-P2-43, 2021

    J-STAGE 

  • Reduced white adipose tissue amount in mice lacking mitochondrial protein p13  [in Japanese]

    Satomi Hara , Ueno Hiroki , Noguchi Masafumi , Matsuo Wakana , Hashimoto Hitoshi , Shintani Norihito

    <p>Mitochondrial protein p13 is a less understood protein possibly related to cardiac pathophysiology. Since mice lacking the p13 (p13-/- mice) showed markedly reduced white adipose tissue (WAT) …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-P2-LB49, 2021

    J-STAGE 

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