Search Results 1-20 of 7233

  • Distribution of Deep Gray Matter Lesions on Magnetic Resonance Imaging in Lymphomatosis Cerebri

    Kobayashi Zen , Tomimitsu Hiroyuki , Shintani Shuzo , Sakai Sawako , Itaya Sakiko , Numasawa Yoshiyuki , Ota Kiyobumi , Akaza Miho , Ueda Yasuhiro , Ogawa Shinichi , Ishihara Shoichiro

    … <p>We herein report the distribution of gray matter lesions on magnetic resonance imaging (MRI) in two patients with lymphomatosis cerebri (LC). … In our patients, the fluid-attenuated inversion recovery sequence of brain MRI demonstrated a bilateral and diffuse high signal intensity, not only in the white matter but also in the thalamus, globus pallidus, putamen, and hippocampus. …

    Internal Medicine, 2021

    J-STAGE 

  • Back pain of orthopaedic surgery patients  [in Japanese]

    門野 夕峰

    日本臨床 = Japanese journal of clinical medicine 78(8), 1407-1412, 2020-08

  • Neurosurgery for brain metastasis from breast cancer

    Tomita Yusuke , Kurozumi Kazuhiko , Fujii Kentaro , Shimazu Yosuke , Date Isao

    … Breast cancer is the most common malignancy among women worldwide, and the main cause of death in patients with breast cancer is metastasis. … Metastasis to the central nervous system occurs in 10% to 16% of patients with metastatic breast cancer, and this rate has increased because of recent advancements in systemic chemotherapy. … Surgical resection continues to play an important role in patients with a limited number of brain metastases and a relatively good performance status. …

    Translational Cancer Research 9(8), 5063-5076, 2020-08

    IR 

  • Complete resection and untethering of the cervical and thoracic spinal dermal sinus tracts in adult patients

    Nishimura Yusuke , Hara Masahito , Natsume Atsushi , Wakabayashi Toshihiko , Ginsberg Howard J

    … Dermal sinus tracts (DSTs) of the cervical and thoracic spine are extremely rare, particularly in adult patients because diagnosis is typically made in the early stage after birth by pediatricians. … These cases should be treated surgically as soon as possible to prevent neurological sequelae. … Both cases had these sinus tracts excised completely and had spinal cord untethered successfully without any neurological deterioration. …

    Nagoya Journal of Medical Science 82(3), 567-577, 2020-08

    IR  DOI 

  • Comparison of Two Different Intensive Care Unit Systems for Severely Ill Children in Japan: Data from the JaRPAC Registry

    Tsukahara Kohei , Naitou Hiromichi , Yorifuji Takashi , Nosaka Nobuyuki , Yamamoto Hirotsugu , Osako Takaaki , Nakao Atsunori , the JaRPAC Study Group

    … Overall, 1,333 pediatric patients were included, with 1,143 patients admitted to PICUs and 190 patients to general ICUs. … Death and unfavorable neurological outcomes occurred less often in the PICU group (adjusted OR: 0.29; …

    Acta Medica Okayama 74(4), 285-291, 2020-08

    IR  DOI 

  • Complete genome analysis and characterization of neurotropic dengue virus 2 cosmopolitan genotype isolated from the cerebrospinal fluid of encephalitis patients

    Ngwe Tun Mya Myat , Muthugala Rohitha , Nabeshima Takeshi , Soe Aung Min , Dumre Shyam Prakash , Rajamanthri Lakmali , Jayawardana Dulani , Attanayake Shanthi , Inoue Shingo , Morita Kouichi

    Neurological symptoms associated with DENV infection have increasingly been reported in both children and adults. … Here, we characterize DENV type 2 (DENV-2) strains, which were isolated from cerebrospinal fluid (CSF) and/or serum of patients with dengue encephalitis. … Among the 5 dengue encephalitis patients examined, 4 recovered and 1 died. … DENV-2 strains were isolated from serum and/or CSF samples of 3 patients. …

    PLOS ONE 15(6), e0234508, 2020-06-18

    IR 

  • Biologic Therapy Options for Crohn's Disease

    ISHIHARA Shunji , MISHIMA Yoshiyuki , KAWASHIMA Kosaku

    … Initially, anti-tumor necrosis factor (TNF)-α antibodies were used for induction and maintenance therapies, and the clinical course of affected patients was dramatically changed because of their efficacy and safety. … Although the efficacy of biologics for CD is widely recognized, how to determine which biologic is appropriate for individual patients remains largely unknown and additional studies are necessary to clarify this issue. …

    Shimane Journal of Medical Science 37(2), 45-50, 2020-06

    IR  DOI 

  • Association between low pH and unfavorable neurological outcome among out-of-hospital cardiac arrest patients treated by extracorporeal CPR: a prospective observational cohort study in Japan

    Okada Yohei , Kiguchi Takeyuki , Irisawa Taro , Yoshiya Kazuhisa , Yamada Tomoki , Hayakawa Koichi , Noguchi Kazuo , Nishimura Tetsuro , Ishibe Takuya , Yagi Yoshiki , Kishimoto Masafumi , Shintani Hiroshi , Hayashi Yasuyuki , Sogabe Taku , Morooka Takaya , Sakamoto Haruko , Suzuki Keitaro , Nakamura Fumiko , Nishioka Norihiro , Matsuyama Tasuku , Sado Junya , Matsui Satoshi , Shimazu Takeshi , Koike Kaoru , Kawamura Takashi , Kitamura Tetsuhisa , Iwami Taku , the CRITICAL Study Group Investigators

    … Background: We aimed to identify the association of pH value in blood gas assessment with neurological outcome among out-of-hospital cardiac arrest (OHCA) patients treated by extracorporeal cardiopulmonary resuscitation (ECPR). … Methods: We retrospectively analyzed the database of a multicenter prospective observational study on OHCA patients in Osaka prefecture, Japan (CRITICAL study), from July 1, 2012 to December 31, 2016. …

    Journal of Intensive Care (8), 2020-05-11

    IR 

  • Postoperative iatrogenic spinal cord herniation: three case reports with a literature review

    Nakashima Hiroaki , Ishikawa Yoshimoto , Kato Fumihiko , Kanemura Tokumi , Shinjo Ryuichi , Ando Kei , Kobayashi Kazuyoshi , Ishiguro Naoki , Imagama Shiro

    … Our data base included 32253 patients who underwent spinal surgery, and among these patients, 3 showed postoperative spinal cord herniation. … Both these patients underwent cervical laminoplasty for degenerative cervical myelopathy; … Her neurological symptoms did not improve after tumor resection, and MRI at 2 months after surgery revealed spinal cord herniation. … All the 3 patients underwent spinal cord reduction surgery; …

    Nagoya Journal of Medical Science 82(2), 383-389, 2020-05

    IR  DOI 

  • Efficacy and safety of valganciclovir in patients with symptomatic congenital cytomegalovirus disease Study Protocol Clinical Trial (SPIRIT Compliant)

    Morioka Ichiro , Kakei Yasumasa , Omori Takashi , Nozu Kandai , Fujioka Kazumichi , Yoshikawa Tetsushi , Moriuchi Hiroyuki , Ito Yoshinori , Oka Akira

    … Background: Congenital cytomegalovirus (CMV) disease, a common mother-to-child infection, can lead to neurological sequelae. …

    Medicine 99(17), e19765, 2020-04

    IR 

  • Molecular mechanisms determining severity in patients with Pierson syndrome

    Minamikawa Shogo , Miwa Saori , Inagaki Tetsuji , Nishiyama Kei , Kaito Hiroshi , Ninchoji Takeshi , Yamamura Tomohiko , Nagano China , Sakakibara Nana , Ishimori Shingo , Hara Shigeo , Yoshikawa Norishige , Hirano Daishi , Harada Ryoko , Hamada Riku , Matsunoshita Natsuki , Nagata Michio , Shima Yuko , Nakanishi Koichi , Nagase Hiroaki , Takeda Hiroki , Morisada Naoya , Iijima Kazumoto , Nozu Kandai

    … Null variants in LAMB2 cause Pierson syndrome (PS), a severe congenital nephrotic syndrome with ocular and neurological defects. … Patients' kidney specimens show complete negativity for laminin β2 expression on glomerular basement membrane (GBM). … In this paper, we report six PS patients: four with mild phenotypes and two with severe phenotypes. …

    Journal of Human Genetics (65), 355-362, 2020-04

    IR 

  • Subcutaneous infusion for patients of intractable neurological diseases in chronic stage wards  [in Japanese]

    麓 直浩 , 浦井 由光 , 原口 俊 , 坂井 研一 , 田邊 康之

    難病と在宅ケア 25(12), 50-53, 2020-03

    Ichushi Web 

  • Vasospasm and Hydrocephalus Following Subarachnoid Hemorrhage Are Less Frequent in Coil Embolization than in Clipping

    Hayashi Kentaro , Ogawa Yuka , Fujimoto Takashi , Iwanaga Mitsuto , Anda Takeo , Matsuo Takayuki

    … Between January 2015 and December 2017, 800 SAH patients were registered from 18 hospitals, and their age, sex, World Federation of Neurological Societies (WFNS) grade, Fisher group, size and location of cerebral aneurysms, treatment methods, incidence of symptomatic vasospasm and shunt-dependent hydrocephalus, and prognosis (discharge or 3 months later) were retrospectively analyzed. … There were 245 (30.6%) male patients and 555 (69.3%) female patients. …

    Journal of Neuroendovascular Therapy, 2020

    J-STAGE 

  • Coronavirus disease 2019 (COVID-19) and headaches  [in Japanese]

    M.D. Ph.D. Suzuki Keisuke

    <p>新型コロナウイルス感染症(coronavirus disease 2019; COVID-19)の大流行に伴い,その対策や感染拡大防止に加え我々の社会的状況も激変しつつある.近年COVID-19に伴う神経症状は稀ではなく,頭痛は主な神経症状として注目されつつある.COVID-19に伴う頭痛の頻度は21臨床研究,8メタアナリシスにより5.6%~70.3%に認めた.一方COVID-1 …

    Rinsho Shinkeigaku 60(9), 589-596, 2020

    J-STAGE 

  • Detection of paroxysmal atrial fibrillation in patient with embolic stroke by active self-management education: a case report  [in Japanese]

    Fukuoka Yasuko , Ogura Aya , Ito Yasuhiro , Mae Chitose , Tomita Kayoko , Omori Toyonori , Kimura Kazumi , Matsumoto Masayasu , Moriyama Michiko

    <p>要旨:症例は65 歳男性.突然の左視野障害を自覚し,受診.頭部MRI 上,右後頭葉に梗塞巣を認め,塞栓性機序を疑ったが,発作性を含め心房細動は見いだされず,embolic stroke of undetermined source としてフォローした.脳梗塞再発予防の疾病管理プログラム研究へ参加し,疾病管理ナースが,不整脈の発見を目標に,血圧と脈拍の自己測定を含むセルフマネジメン …

    Japanese Journal of Stroke 42(5), 406-412, 2020

    J-STAGE 

  • Carotid Endarterectomy Effectively treats Carotid Webs : A Case Report  [in Japanese]

    Chikamatsu Genki , Izumo Tsuyoshi , Morofuji Yoichi , Kanamoto Tadashi , Tateishi Yohei , Horie Nobutaka , Anda Takeo , Tsujino Akira , Matsuo Takayuki

    <p> Carotid webは内頚動脈内に限局的な線維筋性異形成を生じ, 血管狭窄をきたすまれな疾患である. 今回頚動脈内膜剝離術 (CEA) を施行し, 経過良好であった1例を経験した. 症例は70代女性, 突然の左片麻痺, 構音障害をきたし, 右M1に閉塞を認めた. tPA静注療法, 血栓回収療法を行い, TICI2bの再開通を得た. 右内頚動脈起始部に壁不整を認め, その他の脳 …

    Japanese Journal of Neurosurgery 29(9), 652-657, 2020

    J-STAGE 

  • Role of Comprehensive Stroke Centers in Stroke Care  [in Japanese]

    Nishimura Ataru , Iihara Koji

    <p> t-PA静注療法の認可を受けて, 米国ではt-PA静注療法を適正に使用できる施設を認証することの重要性が認識され, t-PA静注療法の普及・整備を目的とした, 一次脳卒中センターの要件が策定され, さらに一次脳卒中センターよりも高度な脳卒中医療を施行できる施設として, 包括的脳卒中センターの要件が発表された. J-ASPECT studyでは, 日本における包括的脳卒中センター …

    Japanese Journal of Neurosurgery 29(9), 625-633, 2020

    J-STAGE 

  • Neurorehabilitation for Functional Recovery  [in Japanese]

    Fujiwara Toshiyuki

    <p> 脳, 脊髄などの中枢神経障害による運動機能障害の回復においては, 脳, 脊髄における可塑的変化が起こっている. 脳における可塑的変化の機序の1つには皮質内抑制の脱抑制が関与し, 脊髄においては脊髄相反性抑制が関与している.</p><p> これらの神経可塑性を誘導し, 機能回復を目指す新しい治療として上肢機能障害に対するbrain machine inte …

    Japanese Journal of Neurosurgery 29(9), 634-638, 2020

    J-STAGE 

  • Telemedicine in Neurosurgery  [in Japanese]

    Ohta Tsuyoshi

    <p> 遠隔医療とは, 双方向性の情報をもとに遠隔地の患者に対して行われる医療行為である. 日本では地方や僻地などの地域医療の充実の観点から重要とされる. 脳神経外科領域では急性期脳卒中診療の適正化が報告されている. 今後の通信技術の発展次第では, 高品質情報をリアルタイムに共有して治療手技も転送できるようになり, 地方での夜間, 休日などの医療資源が手薄になる状況下や高い専門性が要求 …

    Japanese Journal of Neurosurgery 29(9), 619-624, 2020

    J-STAGE 

  • Endovascular Treatment of Patients with Oculomotor Nerve Palsy Induced by Posterior Communicating Artery Aneurysms

    Shimoda Kentaro , Kano Toshikazu , Kurata Genya , Kanazawa Yu , Furuichi Makoto , Yoshino Atsuo

    … Between 2007 and 2019, 8 patients with PComA aneurysms and ONP underwent coiling at our institution. … At the last available clinical follow-up, ONP recovery was complete in 4 patients (50%) and partial in 4 patients (50%). … Patients with partial recovery of ONP had sequelae of eye movement impairment that did not affect daily life. …

    Journal of Neuroendovascular Therapy 14(9), 366-372, 2020

    J-STAGE 

Page Top