Search Results 1-20 of 416

  • Effects of Applicator Type on the Safety and Efficacy of Commercial Minoxidil Products  [in Japanese]

    Todo Hiroaki , Saito Miyuki , Suzuki Hiromichi , Inoue Yutaka , Takayama Kozo , Sugibayashi Kenji

    … Minoxidil was developed as a direct over-the-counter (OTC) drug in 1999 and has long been marketed only by one original company. … However, the shape and type of the containers for these generic products differ from that of the original product, leading to a possibility that the amount of minoxidil applied by patients may differ. …

    Journal of Pharmaceutical Science and Technology, Japan 81(1), 111-120, 2021

    J-STAGE 

  • The Development and Evaluation of Educational Materials for Promoting Adverse Drug Reaction Reporting on OTC Drugs  [in Japanese]

    根本 葵 , 飯嶋 久志 , 杉浦 邦夫 , 小佐野 郁香 , 川崎 裕子 , 若林 進 , 出石 啓治 , 宮崎 長一郎 , 宮﨑 理惠 , 松澤 忍 , 根岸 健一 , 鹿村 恵明

    医薬品安全性学 = Japanese journal of drug safety 6(1), 9-18, 2020-06

    Ichushi Web 

  • Up to the present and the future on fluoride application : How to promote the application of fluoride mouthrinse over the counter and concentrated fluoride dentifrice  [in Japanese]

    眞木 吉信

    日本歯科衛生教育学会雑誌 = The journal of Japan Society of Dental Hygiene Education 11(1), 22-33, 2020-05

    Ichushi Web 

  • CASE REPORTS : Contact Dermatitis by Multiple Components in an Over-the-Counter Topical Antiseptic  [in Japanese]

    小林 祐香莉 , 渡邉 荘子 , 石崎 純子 , 田中 勝

    皮膚科の臨床 62(2), 189-194, 2020-02

    Ichushi Web 

  • A retrospective study on the epidemiological and clinical features of emergency patients with large or massive consumption of caffeinated supplements and over-the-counter cold remedy containing caffeine in Japan  [in Japanese]

    喜屋武 玲子 , 高井 美智子 , 芳賀 佳之

    The Japanese journal of clinical toxicology = 中毒研究 : 日本中毒学会機関誌 33(4), 327-334, 2020

  • Current status of caffeine addiction caused by over-the-counter drugs and its countermeasures : From the perspective of pharmacists  [in Japanese]

    廣瀬 正幸 , 平川 昭彦 , 春日井 大介 , 三井 哲史 , 田島 康介 , 山田 成樹

    The Japanese journal of clinical toxicology = 中毒研究 : 日本中毒学会機関誌 33(1), 41-46, 2020

  • Efficacy and Safety of ST-QT200 in Patients with Common Cold  [in Japanese]

    HARA Hideyuki , UCHIDA Naoki

    … <p><b>Background</b>: ST-QT200 is a newly developed over-the-counter (OTC) cold remedy. … Adverse events (AEs) were collected to assess overall safety of the drug.</p><p><b>Results</b>: Sixty-four (64) patients were enrolled and completed the study. … The improvement in pain-related, febrile and inflammatory symptoms was notable. …

    Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 51(6), 317-323, 2020

    J-STAGE 

  • Effectiveness of Pharmaceutical Care for Inpatients with Eating Disorders who Abuse Laxatives  [in Japanese]

    Yamamoto Yurie , Shoji Masayasu , Hosokawa Mariko , Murakami Masafumi , Tamura Naho , Kawai Keisuke

    <p>摂食障害患者の下剤乱用は予後不良因子の1つである. 入院治療において薬剤師による下剤乱用や便秘に焦点を当てた教育的指導を実施した後, 下剤の処方量と患者の認識の変化, 退院1年後の下剤乱用量について調査した. 下剤乱用患者33名は入院時処方に比較して, 退院処方では刺激性下剤に関して有意な変化を認めなかった (p=0.435) ものの, 入院前の下剤乱用量を考慮すると刺激性下剤の …

    Japanese Journal of Psychosomatic Medicine 60(8), 719-727, 2020

    J-STAGE  Ichushi Web 

  • A Case of Anaphylaxis due to Methyl Ephedrine Hydrochloride  [in Japanese]

    OKUDA Yosuke , KISHIDA Hiroko , KATAOKA Yoko

    <p>　18歳女性。市販感冒薬を内服後に緊急治療を要する呼吸困難と全身に蕁麻疹が出現し，救急治療を受け改善した。アナフィラキシーの原因薬検索目的で当科紹介された。被疑薬はメチルエフェドリンを含む８種の構成成分で構成されている。個々の成分について各々皮膚テスト（プリックテスト，スクラッチチャンバーテスト）・内服誘発テスト施行した。メチルエフェドリン以外の皮膚テスト，内服テストはすべて陰性 …

    Nihon Hifu Meneki Arerugy Gakkai Zasshi 3(2), 326-329, 2020

    J-STAGE  Ichushi Web 

  • A Case of Anaphylaxis Caused by Chlorhexidine Digluconate Applied to the Skin Around a Stoma  [in Japanese]

    HANADA Miho , NAKAGAWA Michiyo , HAMABATA Akemi , AMANO Hiroo

    <p>　62歳女性。尿道癌の化学療法のため泌尿器科に入院。１%クロルヘキシジングルコン酸塩 (CHG) で膀胱瘻を消毒中に呼吸苦, 両手のしびれ, 全身の膨疹, 顔面浮腫が出現しアナフィラキシーを生じた。通常は膀胱瘻に消毒剤は使用していなかったが, 臨時に入院した泌尿器科以外の病棟での発症であった。既往として, 市販のひび・あかぎれ用のCHG含有軟膏を手指に外用していた。0.02%, …

    Nihon Hifu Meneki Arerugy Gakkai Zasshi 3(3), 430-435, 2020

    J-STAGE  Ichushi Web 

  • Two Cases of Widespread Contact Dermatitis to OTC Medicaments  [in Japanese]

    HIRAI Yuka , TAKEI Hanako , KASA Yurina , ITOH Yuta , OHTOSHI Shinpei , NAKADA Tokio

    <p>　症例１ : 50代男性。１ヵ月前に下肢に掻痒感が出現したため液体ムヒ<sup>®</sup>S2aを外用, ２週間前には顔面, 頸部にも皮疹が拡大したため, ムヒアルファ<sup>®</sup>EXに変更したところ症状が増悪した。現症 : 顔面, 頸部に浮腫性紅斑と丘疹を認め, 四肢には丘疹が散在性に多発してい …

    Nihon Hifu Meneki Arerugy Gakkai Zasshi 3(3), 451-455, 2020

    J-STAGE  Ichushi Web 

  • A Case of Allergic Contact Dermatitis Caused by 2-hydroxyethyl Acrylate in Ultraviolet-cured Acrylic Resin:～Possible Sensitization during Accessory Production～  [in Japanese]

    IIJIMA Shigeruko , KOJO Kazumi , TAKAYAMA Noriko

    <p>　64歳女。紫外線硬化アクリル樹脂を用いたアクセサリーの作製中に感作されたアレルギー性接触皮膚炎の１例を報告した。患者は布またはポリエチレン手袋を着用していたが，２週間後の２回目の作製後に手指の軽度の腫脹・疼痛・掻痒を感じた。４週間後の３回目の作製時には，水疱を形成する重篤な皮膚炎を生じた。パッチテストの結果から，感作源は，アクリル樹脂中に含まれる2-ヒドロキシエチルアクリレート …

    Nihon Hifu Meneki Arerugy Gakkai Zasshi 3(2), 362-369, 2020

    J-STAGE  Ichushi Web 

  • Simultaneous Determination of Arbutin and Hydroquinone in Dried Bearberry Leaf Extracts by HPLC

    TSUTAHARA Ryota , NISHIHARA Masakazu , OSUMI Yuko

    … Therefore, this formulation can be considered for commercialization as an over-the-counter (OTC) drug. … Hence, in the current study we established a method for the quantitation of arbutin and hydroquinone in plain extract bearberry formulation. …

    BUNSEKI KAGAKU 69(7.8), 357-362, 2020

    J-STAGE  Ichushi Web 

  • Acute Interstitial Nephritis and Acute Tubular Injury Due to a Transdermal Loxoprofen Patch

    Shinzato Takahiro , Shimizu Toshihiro , Nanmoku Koji , Yagisawa Takashi , Ohara Ken , Kaminaga Hiroaki , Sugase Taro , Masuda Takahiro , Nagata Daisuke , Saki Katano , Kinoshita Yoshitaka , Kubo Taro

    … The NSAID patch had been prescribed after a traffic accident. … He was also receiving a vitamin D analog and taking over-the-counter calcium supplements. … Once these agents were withdrawn, the renal function recovered. … This is the first reported occurrence of biopsy-proven acute interstitial nephritis attributable to NSAID patch usage. …

    Internal Medicine 59(21), 2733-2736, 2020

    J-STAGE 

  • Current status of addicted patients caused by over-the-counter drugs and its countermeasures  [in Japanese]

    HIROSE Masayuki , HIRAKAWA Akihiko , NAKANO Yuko , TAJIMA Kousuke , YAMADA Shigeki

    <p><b>目的</b>：一般用医薬品による急性薬物中毒の現状と地域の薬剤師や薬局の問題点を検討する。<b>方法</b>：過去8年間に一般用医薬品を過量服薬した86例を対象に，年齢・性別，製剤の種類，患者数の推移，致死量摂取例の成分について検討した。また，販売者である地域の薬剤師50 名にアンケート調査を行い，薬剤師や薬局の問題点について …

    Journal of Japanese Society for Emergency Medicine 23(5), 702-706, 2020

    J-STAGE  Ichushi Web 

  • A Survey of Medicine and Health Care Product Use by High School and College Students in Japan  [in Japanese]

    Arai Kunizo , Urata Koki , Hashimoto Masako , Hasumoto Kenyu , Taniyama Toru , Uo Shinya

    <p>石川県内の高校生および大学生による医療用医薬品とヘルスケア商品（一般用医薬品，健康食品，サプリメント）の使用実態をアンケートにより調査した．体の具合が悪くなったとき，医療機関に受診しないで健康食品やサプリメントを利用する者が 18.5％（83 名：449 名の健康食品利用者中）いた．さらに，健康食品で病気は治ると，間違って理解している者が 34.5％（654 名）いた．以上より， …

    The Journal of Community Pharmacy and Pharmaceutical Sciences 12(2), 95-107, 2020

    J-STAGE 

  • Effects of a Disintegrant on the Stability of Solid Oral Formulations Containing Erythritol  [in Japanese]

    Ota Misuzu , Kusano Riho , Hosoya Sayaka , Nakajima Takanori , Arakawa Motoki , Ikeuchi-Takahashi Yuri , Hidaka Shinji

    … <p>Summary: A previous evaluation of the pharmaceutical stability of tablets of acetaminophen (AAP)-containing over-the-counter (OTC) drugs formulated with a combination of the excipients erythritol (ET) and crospovidone (CP) revealed that high-temperature and high-humidity storage conditions caused a delayed release of AAP. …

    The Journal of Community Pharmacy and Pharmaceutical Sciences 12(2), 84-94, 2020

    J-STAGE 

  • Radiological and pathological patterns of drug-induced lung injury  [in Japanese]

    BABA Tomohisa , TAKEMURA Tamiko , IWASAWA Tae , OGURA Takashi

    … <p>Drug-induced lung injury is defined as a lung injury that results from the specific use of a drug including over-the-counter drugs, herbal medicines, supplements, and illegal narcotics. … Drug-induced interstitial lung disease that is one of the most common types of drug -induced lung injury occasionally causes fatal outcome. …

    Annual Meeting of the Japanese Society of Toxicology 47.1(0), S8-2, 2020

    J-STAGE 

  • What Kind of Information Do Patients and Consumers Want from the Internet About Medicines?  [in Japanese]

    Kawada Ai , Kishimoto Keiko

    … <p>The purpose of this study was to examine how pharmacists can help patients and consumers to obtain appropriate drug information online. … "Yahoo! Chiebukuro", the largest knowledge sharing community in Japan, was surveyed. … We extracted questions related to drugs and healthcare posted in the period of August 1-7, 2017. … The survey period was from January to April 2019. …

    Japanese Journal of Social Pharmacy 39(1), 12-18, 2020

    J-STAGE 

  • Survey of University Students' Self-medication Interest and Energy Drink Use Trend: A Pilot Study  [in Japanese]

    Hatabu Asuka , Toda Shyohei , Tanide Sayaka , Uejima Etsuko , Takagi Tatsuya , Ueda Mikiko

    … Owing to their influence on the health of young people, energy drinks (a caffeine-containing beverage) have attracted attention. … The results showed 28.3% of the students were interested in self-medication and 4.4% were knowledgeable on the self-medication tax system. … Additionally, 73.9% of them used over-the-counter (OTC) drugs, especially common cold medicines (65.0%). …

    Japanese Journal of Social Pharmacy 39(1), 2-11, 2020

    J-STAGE 

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