Search Results 1-20 of 1444

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Preoperative Improvement in Physical Function by Comprehensive Rehabilitation Leads to Decreased Postoperative Complications in Gastrointestinal Cancer Patients

Hara Tsuyoshi , Kogure Eisuke , Kubo Akira , Kakuda Wataru

… The surgical duration, blood loss, and blood transfusion data were collected. … Baseline laboratory information, including C-reactive protein levels, serum albumin levels, platelet count, white blood cell count, and the estimated glomerular filtration rate, was recorded.Results: The frequency of PCs was negatively correlated to the change in the 6MWT (β=−0.36) and positively correlated to the surgical duration (β=0.41). …

Progress in Rehabilitation Medicine 6(0), n/a, 2021

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2

Acquired amegakaryocytic thrombocytopenia after durvalumab administration

Suyama Takahiro , Hagihara Masao , Kubota Naoto , Osamura Yoshiyuki , Shinka Yoko , Miyao Naoki

… Most cases of thrombocytopenia induced by ICIs have revealed a pathophysiologic mechanism of immune thrombocytopenia with increased platelet destruction and preserved megakaryocytes. … Two weeks after the second cycle, his platelet count decreased to 2.1 × 104/μL. …

Journal of Clinical and Experimental Hematopathology, 2021

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Eltrombopag in Combination with Rabbit Anti-thymocyte Globulin/Cyclosporine A in Immunosuppressive Therapy-naïve Patients with Aplastic Anemia in Japan

Imada Kazunori , Kumagai Akiko , Matsuda Akira , Nakao Shinji , Obara Naoshi , Iida Hiroatsu , Imajo Kenji , Maeda Tetsuo , Usuki Kensuke , Fanghong Zhang , Hombo Yosuke , Tajima Takeshi

… Among transfusion-dependent patients, 66.7% (4/6) and 62.5% (5/8) became red blood cell- and platelet-transfusion independent, respectively. …

Internal Medicine, 2021

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Blood transfusion therapy using platelet and plasma products [in Japanese]

高見昭良

日本内科学会雑誌 109(7), 1392-1399, 2020-07-10

Ichushi Web
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Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review

Akagi Kazumasa , Miyazaki Taiga , Oshima Kazuhiro , Umemura Asuka , Shimada Satoshi , Morita Kouichi , Senju Hiroaki , Tashiro Masato , Takazono Takahiro , Saijo Tomomi , Kurihara Shintaro , Sekino Motohiro , Yamamoto Kazuko , Imamura Yoshifumi , Izumikawa Koichi , Yanagihara Katsunori , Uda Akihiko , Morikawa Shigeru , Yoshikawa Tomoki , Kurosu Takeshi , Shimojima Masayuki , Saijo Masayuki , Mukae Hiroshi

… He was treated with multimodal therapy, including platelet transfusion, antimicrobials, antifungals, steroids, and continuous hemodiafiltration. …

BMC Infectious Diseases 20(1), 281, 2020-04-15

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6

Pulmonary Edema and Decreased Blood Pressure due to Blood Type-unmatched Platelet Transfusion during Pulmonary Surgery for Chest Injury [in Japanese]

岡里紗 , 芝順太郎 , 平幸輝 , 竹内護

麻酔 = The Japanese journal of anesthesiology : 日本麻酔科学会準機関誌 69(4), 403-405, 2020-04

Ichushi Web
7

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

Suzuki Daisuke , Flahou Charlotte , Yoshikawa Norihide , Stirblyte Ieva , Hayashi Yoshikazu , Sawaguchi Akira , Akasaka Marina , Nakamura Sou , Higashi Natsumi , Xu Huaigeng , Matsumoto Takuya , Fujio Kosuke , Manz Markus G. , Hotta Akitsu , Takizawa Hitoshi , Eto Koji , Sugimoto Naoshi

… The ex vivo production of platelets depleted of human leukocyte antigen class I (HLA-I) could serve as a universal measure to overcome platelet transfusion refractoriness caused by HLA-I incompatibility. … HLA-KO iPLATs were deficient for all HLA-I but did not elicit a cytotoxic response by NK cells in vitro and showed circulation equal to wild-type iPLATs upon transfusion in our newly established Hu-NK-MSTRG mice reconstituted with human NK cells. …

Stem Cell Reports 14(1), 49-59, 2020-01-14

IR
8

MASSIVE TRANSFUSION PROTOCOL FOR THE MANAGEMENT OF MASSIVE BLEEDING AND ITS RELATED ADVERSE EVENTS [in Japanese]

射場敏明 , 相星淳一

日本外科学会雑誌 = Journal of Japan Surgical Society 121(4), 454-457, 2020

Ichushi Web
9

The Thrombopoietin Receptor Agonist Lusutrombopag Is Effective for Patients with Chronic Liver Disease and Impaired Renal Function

Takeuchi Hirohito , Furuichi Yoshihiro , Yoshimasu Yu , Kasai Yoshitaka , Abe Masakazu , Sugimoto Katsutoshi , Itoi Takao

… The purpose of this study was to assess the efficacy of lusutrombopag and identify predictors associated with increase in platelet count. … The primary endpoint was a satisfactory increase in platelets (greater than 1.0 × 104/μL from baseline) in the absence of platelet transfusion. …

Journal of Nippon Medical School 87(6), 325-333, 2020

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10

Acute thrombocytopenia after obinutuzumab administration in a patient with relapsed follicular lymphoma [in Japanese]

SAKAI Kohei , MATSUMURA Takuro , HAMADA Risako , TOMINAGA Takayuki , TAKAHASHI Toru

… Obinutuzumab (OBZ) and bendamustine (GB) therapy was administered for her lymphoma, and thrombocytopenia requiring platelet transfusion was observed after the first course. …

Rinsho Ketsueki 61(11), 1616-1619, 2020

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11

A case of Bernard-Soulier Syndrome that proved to be refractory to platelet transfusion after invasive dental treatment [in Japanese]

NOHARA Kana , KUROHARA Kazuto , OKUMURA Kenya , YANASE Shigeaki , KONDO Seiji , ARAI Naoya

… Bernard-Soulier syndrome (BSS) is an inherited thrombocytopenia caused by deficiency of GPIb/IX/V glycoprotein complexes that are necessary for platelet aggregation. … We report a case of BSS that was proved to be platelet transfusion refractory (PTR) following invasive dental treatment. …

Japanese Journal of Oral and Maxillofacial Surgery 66(9), 424-430, 2020

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12

New diagnostic system, registry, and sample bank for congenital thrombocytopenia in Japan [in Japanese]

Ishiguro Akira , Uchiyama Toru , Kunishima Shinji

… Congenital thrombocytopenia (CT) is a heterogeneous group of bleeding disorders caused by inherited defects in platelet production. … Platelet transfusion is contraindicated for ITP, but remains a key option for CT. …

The Japanese Journal of Pediatric Hematology / Oncology 57(3), 227-234, 2020

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13

Severe consumption thrombocytopenia with rheumatoid arthritis approximately 2 weeks after tocilizumab therapy: A case report

Kiyonaga Yasuhiro , Sako Noriaki , Abe Itomi , Tatsukawa Hiroshi

… Her blood platelet count markedly decreased from 340,000/µl（before administration）to 6,000/µl（after administration）, and she was hospitalized on the same day. … On the day of hospitalization, intravenous immunoglobulin infusion and prednisolone（50 mg/day）administration were initiated together with platelet transfusion. …

Clinical Rheumatology and Related Research 32(3), 238-244, 2020

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14

Neck dissection in a patient treated with refractory idiopathic thrombocytopenic purpura who received a thrombopoietin receptor agonist and γ-globulin preoperatively: a case report [in Japanese]

UETA Miho , TAKAOKA Kazuki , NISHIDA Michiyo , YOSHIKAWA Kyohei , NOGUCHI Kazuma , KISHIMOTO Hiromitsu

… We report a case of refractory idiopathic thrombocytopenic purpura (ITP) in a patient with upper gingival carcinoma treated by modified radical neck dissection who received a thrombopoietin receptor agonist and γ-globulin before operation to increase the platelet count and control hemostasis. … The preoperative laboratory tests showed platelet counts of 1.7〜3.1×104/μL. … However, the platelet count did not increase. …

Japanese Journal of Oral and Maxillofacial Surgery 66(8), 382-387, 2020

J-STAGE Ichushi Web
15

Two Episodes of Transfusion-related Acute Lung Injury (TRALI) Occurring within a Short Period

Akagi Yuina , Sonoki Takashi , Murata Shogo , Yamashita Yusuke , Tanaka Ken , Hiroi Takayuki , Mushino Toshiki , Hosoi Hiroki , Nishikawa Akinori , Tamura Shinobu

… Transfusion-related acute lung injury (TRALI) is a non-hemolytic adverse reaction that occurs ≤6 hours after receiving a transfusion. … A 72-year-old man with leukemia developed severe hypoxemia after platelet transfusions on two occasions within a 4-day period. … During the first episode, the transfused platelet preparation was positive for anti-human-leukocyte antigen antibodies. …

Internal Medicine 59(20), 2577-2581, 2020

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16

WASHING PLATELETS TWICE WITH A BICARBONATED RINGER'S SOLUTION SIGNIFICANTLY REDUCES PLASMA PROTEIN LEVELS WHILE MAINTAINING PLATELET QUALITY [in Japanese]

Oikawa Shinji , Minegishi Masayoshi , Endo Kimika , Kawashima Wataru , Kosunago Satoshi , Murokawa Hiroyuki , Suzuki Ko , Shimizu Hiroshi

Japanese Journal of Transfusion and Cell Therapy 66(4), 664-667, 2020

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17

Intracerebral Hemorrhage after Endovascular Treatment of Unruptured Intracerebral Aneurysm: A Case Report and Review of the Literature

TUCKER Adam , MIYACHI Shigeru , OHNISHI Hiroyuki , HIRAMATSU Ryo , KUROIWA Toshihiko

… However, for severe hemorrhagic cases, platelet transfusion, discontinuation of DAPT to single antiplatelet therapy, and surgical intervention should be considered. …

Surgery for Cerebral Stroke 48(2), 129-133, 2020

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18

Management of idiopathic thrombocytopenic purpura (ITP) in pregnancy [in Japanese]

TAKASE Aki , TACHIBANA Daisuke , FUDABA Megumi , TAHARA Mie , HAMURO Akihiro , NAKANO Akemi , MISUGI Takuya , KOYAMA Masayasu

… Comparison of perinatal events showed a significant difference only in maternal minimum platelet count : that of patients diagnosed with ITP during pregnancy [5.0 (1.2-9.0)× 104/μl] [median (range)] was significantly lower than that of patients diagnosed before pregnancy [9.1 (1.6-21.1)×104/μl] (p=0.046). …

ADVANCES IN OBSTETRICS AND GYNECOLOGY 72(3), 216-223, 2020

J-STAGE Ichushi Web
19

Successful Treatment with Edoxaban for Disseminated Intravascular Coagulation in a Case of Aortic Dissection Complicated with Immune Thrombocytopenic Purpura

Uemura Shun , Kobayashi Hironori , Seki Yoshinobu , Okoshi Yuki , Sone Hirohito , Nomoto Nobuhiko

… However, her bleeding tendency caused by DIC worsened despite the rapid recovery of her platelet count, and the required amount of fresh-frozen plasma for transfusion increased. …

Internal Medicine 59(16), 2035-2039, 2020

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20

Manufacturing of platelets from human adipose tissue-derived mesenchymal stem cell line for future clinical application [in Japanese]

Matsubara Yumiko

… Platelets are released from mature megakaryocytes (MKs) and are used for therapeutic application, especially platelet transfusion. … Platelet concentrates used for platelet transfusions are currently supplied by volunteer donors. … Due to their short shelf life (4 days in Japan and 5 days in US), however, donor-dependent platelet concentrates are associated with practical problems, such as the limited supply and the risk of infection. …

Japanese Journal of Thrombosis and Hemostasis 31(4), 432-438, 2020

J-STAGE Ichushi Web

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