Search Results 1-20 of 762

  • Rosiglitazone attenuates high glucose-induced proliferation, inflammation, oxidative stress and extracellular matrix accumulation in mouse mesangial cells through the Gm26917/miR-185-5p pathway

    Zhao Dongbo , Guo Junli , Liu Lingping , Huang Ying

    … The expression of Gm26917 and microRNA-185-5p (miR-185-5p) was detected by quantitative real-time polymerase chain reaction (qPCR). … The interaction between Gm26917 and miR-185-5p was validated by dual-luciferase reporter assay, RNA immunoprecipitation (RIP) assay and pull-down assay. …

    Endocrine Journal, 2021


  • A Smartphone Application as a Telemedicine Tool for Stroke Care Management

    TAKAO Hiroyuki , YEH Yuchih , KARAGIOZOV Kostadin , FISHER Marc , IGUCHI Yasuyuki , MURAYAMA Yuichi , SAKAI Kenichiro , MITSUMURA Hidetaka , KOMATSU Teppei , YUKI Ichiro , TAKESHITA Kohei , SAKUTA Kenichi , ISHIBASHI Toshihiro , SAKANO Teppei

    … JOIN has key functions that may improve the care of stroke patients, including the ability to (1) exchange information such as patient data and medical images in real-time throughout the entire process of patient management; … and (3) facilitate real-time interaction of all team members via text, audio, and a video chat system. …

    Neurologia medico-chirurgica, 2021


  • ATP-binding Cassette (ABC) Transporter Proteins in Highly Terbinafine-resistant Strains of <i>Trichophyton indotineae</i> (Former Species Name: <i>Trichophyton interdigitale</i>)

    Kano Rui

    … genes by real-time quantitative PCR analysis, given the known interaction of the corresponding proteins with antifungals and the efflux blocker tacrolimus (FK506). … The interaction between TRF and FK506 on antifungal activity was not detected in TRF-resistant strains. …

    Medical Mycology Journal 62(1), 21-25, 2021


  • miR-132 mediates cell permeability and migration by targeting occludin in high-glucose -induced ARPE-19 cells

    Wang Shan-Shan , Liao Xing , Liu Fei , Zhang Qian , Qiu Jing-Jing , Fu Shu-Hua

    … Different miRNA and mRNA expression levels were determined by quantitative real-time polymerase chain reaction (RT-qPCR). … The interaction between occludin and miR-132 was confirmed by a dual-luciferase reporter assay. …

    Endocrine Journal, 2021


  • Posttraumatic Osteoarthritis of Temporomandibular Joint in Miniature Pigs

    Sun Ning-Ning , He Dong-Mei , Yang Chi , Zhou Qing

    … The production of Ihh, PTHrP, and Runx2 was detected by immunohistochemistry staining and real-time polymerase chain reaction (PCR) at weeks 4 and 12 post-surgery. … Our findings suggested that the interaction mechanism among Ihh, PTHLH/PTHrP, and Runx2 is activated when posttraumatic osteoarthritis (PTOA) occurs, but how they regulate each other remains to be investigated.</p> …

    Journal of Hard Tissue Biology 30(1), 79-84, 2021


  • Knockdown of plasmacytoma variant translocation 1 (PVT1) inhibits high glucose-induced proliferation and renal fibrosis in HRMCs by regulating miR-23b-3p/early growth response factor 1 (EGR1)

    Yu Dongmei , Yang Xiaohong , Zhu Yong , Xu Fenyan , Zhang Hong , Qiu Zhiqiang

    … The expression of PVT1, miR-23b-3p, early growth response factor 1 (EGR1), Fibronectin (FN), Collagen IV (Col IV), alpha smooth muscle actin (α-SMA), E-cadherin, and vimentin, transforming growth factor (TGF)-β1 was examined by quantitative real-time polymerase chain reaction (qRT-PCR). … The interaction between miR-23b-3p and PVT1 or EGR1 was predicted by starBase or TargetScan and confirmed by the dual luciferase reporter assay. …

    Endocrine Journal, 2021


  • Realization of Simultaneous Decision Making, Path Planning and Motion Control for Lane-changing Based on Nonlinear Model Predictive Control  [in Japanese]

    Honda Kohei , Okuda Hiroyuki , Suzuki Tatsuya


    Transactions of Society of Automotive Engineers of Japan 52(1), 100-105, 2021



    ISHIKAWA Daichi , FUKUDA Tomohiro , YABUKI Nobuyoshi

    … However, their 3D virtual models have to be made in advance, this is why they cannot represent shapes changing in real-time like 3D physical objects.</p><p> Point clouds are clusters of points that generally have their position as an XYZ coordinate with RGB values. … They can represent 3D surfaces in the real world. …

    Journal of Environmental Engineering (Transactions of AIJ) (778), 1017-1026, 2020-12


  • The Feeling Is Mutual: Clarity of Haptics-Mediated Social Perception Is Not Associated With the Recognition of the Other, Only With Recognition of Each Other

    Tom Froese , Leonardo Zapata-Fonseca , Iwin Leenen , Ruben Fossion

    … We investigated this proposal using the perceptual crossing paradigm, in which pairs of players are required to locate each other in an invisible one-dimensional virtual space by using a minimal haptic interface.We recorded and analyzed the real-time embodied social interaction of 10 pairs of adult participants. …

    Frontiers in Human Neuroscience (14), 560657, 2020-09-04


  • Spatiotemporally tracking of nano-biofilaments inside the nuclear pore complex core

    Mahmoud Shaaban Mohamed , Masaharu Hazawa , Akiko Kobayashi , Laurent Guillaud , Takahiro Watanabe-Nakayama , Mizuho Nakayama , Hanbo Wang , Noriyuki Kodera , Masanobu Oshima , Toshio Ando , Richard W. Wong

    … In general, flexible biofilaments are expected to be tangled and knotted during their motion and interaction. … However, filament knotting visualization in real-time and space has yet to be visualized at the nanoscale. …

    Biomaterials (256), 120198, 2020-06-23


  • Signaling a turn at talk: A Conversation Analysis Approach to Teaching Classroom Interactions

    Derek N. CANNING

    会話は,第二ヶ国語の学習者にとって基礎的な技術である。しかし,大学以上の英語スピーキングの授業には,自然で気楽に会話へと参加するために必要な語用論的能力を育てるための,包括的な方法論が欠けている。Conversation Analysis(会話分析)は第二言語習得の研究者の間で,会話の研究に新鮮な見識をもたらすという理由で注目を集めている。会話分析の研究は,それによって会話者が会話を順番に並べるた …

    聖学院大学論叢 = The Journal of Seigakuin University 第32巻(第2号), 183-203, 2020-03-15

    IR  DOI 

  • Real time 3D image transfer display for haptic-optical interaction system on the whole-body  [in Japanese]

    芹澤 洸希 , 藤原 正浩 , 牧野 泰才 , 篠田 裕之

    電気学会研究会資料. PI = The papers of Technical Meeting on "Perception Information", IEE Japan, 2020(20-32), 9-12, 2020-03-02

  • Investigating real-time social interaction in pairs of adolescents with the Perceptual Crossing Experiment

    Karlijn S. F. M. Hermans , Zuzana Kasanova , Leonardo Zapata-Fonseca , Ginette Lafit , Ruben Fossion , Tom Froese , Inez Myin-Germeys

    … The study of real-time social interaction provides ecologically valid insight into social behavior. … The objective of the current research is to experimentally assess real-time social contingency detection in an adolescent population, using a shortened version of the Perceptual Crossing Experiment (PCE). …

    Behavior Research Methods, 2020-02-19


  • Micromanipulation of amyloplasts with optical tweezers in <i>Arabidopsis</i> stems

    Abe Yoshinori , Meguriya Keisuke , Matsuzaki Takahisa , Sugiyama Teruki , Yoshikawa Hiroshi Y. , Morita Miyo Terao , Toyota Masatsugu

    … Because amyloplasts are in close proximity to vacuolar membranes in endodermal cells, their physical interaction could be visualized in real time. …

    Plant Biotechnology 37(4), 405-415, 2020


  • Aryl Radical Addition to Curvatures of Carbon Nanohorns for Single-Molecule-Level Molecular Imaging

    Kamei Ko , Shimizu Toshiki , Harano Koji , Nakamura Eiichi

    … <p>Real-time imaging of the dynamics of single molecules and molecular assemblies with atomic-resolution electron microscopy is an emerging experimental methodology to obtain single-molecule-level information on molecular motions and reactions. … We can introduce a variety of aromatic moieties including substituted carbo- and heteroaromatics, which can capture molecules from their solution through amide bond formation and van der Waals interaction.</p> …

    Bulletin of the Chemical Society of Japan 93(12), 1603-1608, 2020


  • Image Analysis of Intraoperative Instrument-Organ Interaction to Improve the Levels of Autonomy of Surgical Assistant Robots  [in Japanese]

    NISHIKAWA Atsushi , IWAMOTO Noriyasu , KAWAI Toshikazu , SUZUKI Hisashi , KATAI Hitoshi

    <p>内視鏡手術は,術者により行われる内視鏡画像に基づく手術器具と臓器のインタラクションであり,両者のインタラクションに関する定量的な情報を実時間で抽出する技術は,術者を補佐する手術支援ロボットの自律レベル向上にきわめて有用である.本稿では,新学術領域研究「多元計算解剖学」の公募研究A03-KB102(デプス画像を実時間で生成可能なステレオ内視鏡に基づく手術支援ロボットの自律制御)とし …

    Medical Imaging Technology 38(5), 228-235, 2020



    Fauzan Alfi Agirachman , Michihiko Shinozaki

    … But to bring it to virtual environment with VR, additional interaction model is required to developed. … In this research, we explore the interaction model inside a VR environment with a BIM model as a digital entity connected with its physical counterparts connect to the model through IoT devices simulated as real-time cloud database. …

    SEATUC journal of science and engineering 1(2), 26-31, 2020


  • Simultaneous and real-time quantification of multiple drugs with a needle-type diamond electrode  [in Japanese]

    Sawamura Seishiro , Ogata Genki , Kuwabara Sayaka , Kato Rito , Asai Kai , Razvina Olga , Einaga Yasuaki , Hibino Hiroshi

    <p>生体に投与した薬物が、臓器局所においてどのような濃度動態を示すかを定量することは、薬の作用を理解する上で鍵となる。臨床では、多くの疾患において、複数の薬物が併用されるが、その組み合わせによっては相互作用が起こり、単剤で投与した時とは異なる振る舞いを示す。従って、適切な多剤投与法を理論的に設計するためには、複数の薬物をリアルタイムに測り分ける手法が必要である。本研究では、針状ダイヤ …

    Transactions of Japanese Society for Medical and Biological Engineering Annual58(Abstract), 461-461, 2020


  • MiR-182-5p Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by ox-LDL Through Targeting PAPPA

    Jin Chaolong , Zhang Dingxin , Wang Di , Wang Tingting , Yang Fang , Yang Ying , Wang Xinglong , Wu Liping , Xu Yue , Gao Shan , Li Dayuan , Shi Xuegong , Hu Zhangyue , Wang Chunmiao , Xiao Jie , Sheng Zhe , Ding Zhifeng

    … <p>This study aims to analyze the expression level and correlation of miR-182-5p and its target gene PAPPA in coronary atherosclerosis (CAD).</p><p>Real time PCR, ELISA, and Western blotting methods were used to detect the expression levels. …

    International Heart Journal 61(4), 822-830, 2020


  • Tensegrity representation of microtubule objects using unified particle objects and springs

    Pramudwiatmoko Arif , Gutmann Gregory , Ueno Yutaka , Kakugo Akira , Yamamura Masayuki , Konagaya Akihiko

    … Common media to show the experimental results of molecular objects is still lack of observer interaction to understand it intuitively. … In order to overcome this lack of interaction, this research takes tensegrity representation of molecular objects reproducing experimental results and creates interactive 3D objects to be presented in a virtual reality (VR) environment. …

    Chem-Bio Informatics Journal 20(0), 19-43, 2020


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