Search Results 1-20 of 266

  • Application for Clinical Guideline Assessment by Fluorescent Measurements of Sensitizer Molecule in Tumor  [in Japanese]

    Miyoshi Norio , Kaneko Sadao , Kitai Ryuhei , Tsutsumi Koutarou , Sakurai Yoshinori , Asayama-Kosaka Sachiko , Inoue Keiji , Okada Shigetoshi

    <p>本研究は脳腫瘍の術中蛍光診断(Photodynamic diagnosis: PDD)にて切除組織および凍結切片の症例標本を使用して,蛍光分光高度計による定量的蛍光計測を行い,その蛍光強度から濃度換算した蛍光代謝物の濃度と外科病理生検結果を悪性グレードに分けて,それらの相関性を検討した.その結果,計測した濃度はAstrocytoma gradesの変化につれ指数関数的に増大した. …

    Nippon Laser Igakkaishi, 2020

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  • Nano-scale measurement and thermo-physical property of polymers in super-cooled melt using single-molecule tracking assisted by statistical machine learning  [in Japanese]

    松田 佑

    旭硝子財団助成研究成果報告 Reports of research assisted by the Asahi Glass Foundation, 1-5, 2019

  • Study on nanoparticle sizing method by using fluorescence probe:-Influence of solvent viscosity on translational diffusion coefficient -  [in Japanese]

    AKAHOSHI Keisuke , HAYASHI Terutake , KUROKAWA Shuhei , KUSABA Hiroki

    … <p>Fluorescence correlation spectroscopy (FCS) is one of the fluorescence measurement methods, and it is possible to observe the dynamic characteristics of fluorescent molecules that perform Brownian motion in liquid. … This measurement method has the potential to realize in-liquid measurement of nanoparticles with multimodality and polydispersity which is difficult to observe with conventional measuring instruments. …

    The Proceedings of Conference of Kyushu Branch 2019.72(0), C33, 2019

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  • Dynamics of Rubbery Chains at a Model Filler Interface  [in Japanese]

    KAWAGUCHI Daisuke , TANAKA Keiji

    … <p>The rotational relaxation time of a fluorescent molecule dispersed in rubbery polymers was characterized by time-resolved fluorescence anisotropy (TRFA) measurement and an attempt was made to quantitatively combine it with the segmental relaxation time of the corresponding polymer obtained by dielectric relaxation spectroscopy.<b> …

    NIPPON GOMU KYOKAISHI 92(9), 357-362, 2019

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  • Measuring Dissipation of Molecular Motor Kinesin  [in Japanese]

    ARIGA Takayuki , TOMISHIGE Michio , MIZUNO Daisuke

    … The nonequilibrium energetics of single molecule kinesin were investigated by measuring the motion of an attached probe particle and its response to external forces with optical tweezers. … Here we introduce the theoretical basis of the dissipation measurement and our recent experimental results, discussing the physiological implications of the hidden dissipation in the kinesin motor.</p> …

    Seibutsu Butsuri 59(6), 300-304, 2019

    J-STAGE  Ichushi Web 

  • Maintenance Properties of Enzyme Molecule Stereostructure at High Temperature by Adsorption on Organo-Modified Magnetic Nanoparticle Layer Template

    Yunoki Takeru , Kimura Yusuke , Fujimori Atsuhiro

    … When the bio-adsorbed single particle layer was transferred onto the solid substrate, an infra-red (IR) band derived from the adsorbed species was confirmed in this multi-particle layer. … From the IR measurement under heating, it was found that the secondary structure of the adsorbed lysozyme enzyme was maintained up to about 100 °C by substrate adsorption. …

    Bulletin of the Chemical Society of Japan 92(10), 1662-1671, 2019

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  • Dynamic Measurement Method for Bio-molecular Interactions by Using Centrifugal Force

    OTAKE Mao , UKITA Yoshiaki

    … <p>Measurement of single molecule interaction is performed by various micromanipulation techniques. … However, a complex operation is required to perform the measurement, so the measurement throughput is low and a large amount of time is required for statistical analysis. …

    Analytical Sciences 35(10), 1123-1127, 2019

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  • Direct Observation of Charge Density Distribution―New Development of Precise Structure Analysis Using Synchrotron Radiation X-ray―  [in Japanese]

    Sawa Hiroshi

    <p>電気を流す有機物を合成する.これが「有機物は絶縁体である」という通常の常識を破る化学者の挑戦の一つであった.有機物は基本的に原子間の結合に持てる電子を使ってしまって,導電性という自由度を失っている.ところが,分子を形成する分子軌道の中で,フロンティア軌道の電子(いわゆる価電子)に自由度が残されるとき,金属的電気伝導だけでなく超伝導などのエキゾチックな物性を示すことがある.物質を構 …

    Butsuri 74(1), 14-23, 2019

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  • Control of single-molecule junction and conductance measurement  [in Japanese]

    奥山 弘

    固体物理 53(11), 673-680, 2018-11

  • Synthesis of furan dimer-based polyamides with a high melting point

    Miyagawa Naoki , Suzuki Toyoko , Okano Kentaro , Matsumoto Takuya , Nishino Takashi , Mori Atsunori

    … Polyamide composed of furan dimer, which is prepared from biomass-derived organic molecule 2-furfural, is synthesized. … Measurement of the melting point was performed resulting to exhibit a higher temperature compared with the related polyamide bearing a single furan ring composed of furan-2,5-dicarboxylic acid (FDCA). …

    Journal of Polymer Science Part A: Polymer Chemistry 56(14), 1516-1519, 2018-07-15

    IR 

  • Electrostatics in Control, Manipulation and Measurement of Single Bio-molecule and Cell  [in Japanese]

    水野 彰

    静電気学会誌 42(4), 150-155, 2018-07

  • Space selective crystal growth induced single crystalline metal oxide nanowires and their nanodevice applications  [in Japanese]

    YANAGIDA Takeshi , NAGASHIMA Kazuki , TAKAHASHI Tsunaki

    <p>機能物性の宝庫である金属酸化物を「結晶成長の空間選択性」により,基板上の狙った空間位置のみに高品質な単結晶ナノワイヤ構造やヘテロナノワイヤ構造として設計し,1本の単結晶ナノワイヤ物性測定,新しい酸化物ナノワイヤデバイス(ナノワイヤメモリスタ,ナノワイヤ熱電素子,ナノワイヤ生体分子分析,ナノワイヤ分子認識センサ)へと展開してきた筆者らの一連の研究内容について紹介する.</p& …

    Oyo Buturi 87(1), 29-33, 2018

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  • Evaluation of the Kinetic Property of Single-Molecule Junctions by Tunneling Current Measurements

    HARASHIMA Takanori , HASEGAWA Yusuke , KIGUCHI Manabu , NISHINO Tomoaki

    … <p>We investigated the formation and breaking of single-molecule junctions of two kinds of dithiol molecules by time-resolved tunneling current measurements in a metal nanogap. … The resulting current trajectory was statistically analyzed to determine the single-molecule conductance and, more importantly, to reveal the kinetic property of the single-molecular junction. …

    Analytical Sciences 34(6), 639-641, 2018

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  • Measurement of Electron Transfer within a Single Supramolecular Assembly Containing a Biological Molecule

    KOZAKAI Takafumi , HARASHIMA Takanori , KIGUCHI Manabu , NISHINO Tomoaki

    … <p>We report on a method to measure the electron transport of a single molecular assembly by scanning tunneling microscopy (STM). … The STM molecular tip together with a chemically modified substrate was utilized to form an assembly with a single target molecule. … This method was successfully applied to a heme peptide to reveal the transport property of a single peptide-containing assembly. …

    Analytical Sciences 34(5), 521-523, 2018

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  • Photochemical Reaction Using Aminobenzenethiol Single Molecular Junction

    Matsuzawa Y. , Kaneko S. , Fujii S. , Nishino T. , Kiguchi M. , Tsukagoshi K.

    … The ABT single-molecule junction was formed at the nanogap of the MCBJ and the formation was confirmed by the electronic transport measurement including current versus bias voltage characteristics. …

    e-Journal of Surface Science and Nanotechnology 16(0), 137-141, 2018

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  • Synthesis of Anion-Mixed Crystals of Assembled Complexes Bridged by 1,2-Bis(4-pyridyl)ethane and the Ligand Field of Fe(NCS)(NCBH<sub>3</sub>) Unit

    Dote Haruka , Kaneko Masashi , Inoue Katsuya , Nakashima Satoru

    … Some structures are determined by using single crystal X-ray structural analysis. … Superconducting quantum interference device (SQUID) measurement and Mössbauer spectroscopy reveal that the complexes show spin-crossover (SCO) phenomenon and the relative area of the low-spin state is more than the expected value. … The existence of Fe(NCS)(NCBH<sub>3</sub>) is supported by the results of SQUID measurement and density functional theory (DFT) calculation. …

    Bulletin of the Chemical Society of Japan 91(1), 71-81, 2018

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  • Surface Enhanced Raman Scattering from a Single Molecule  [in Japanese]

    Kaneko Satoshi , Kiguchi Manabu

    <p>単一分子の状態を調べ,動かし,利用することはナノテクノロジーの究極の目的である.現在までにSTMをはじめとする様々な単分子計測,操作技術が開発されてきた.しかし,室温で物性・機能が発現している単分子をそのまま観測することは今でも困難である.我々は,室温で単分子を計測できる手法として表面増強ラマン散乱(SERS)に注目している.SERSは金属ナノ構造体に形成される光増強場を利用した …

    Butsuri 72(5), 328-333, 2017

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  • Measurement of chemical potential difference of ATP hydrolysis from single-molecule observation of F1-ATPase  [in Japanese]

    Tobita Naomichi , Muneyuki Eiro , Nakayama Yohei

    <p>ATPの加水分解によって駆動される回転分子モーターF1-ATPaseのエネルギー論を調べた。特に駆動力である化学ポテンシャルの大きさを一分子実験によって決定するために、回転1自由度の有効ポテンシャルによる記述に基づき、回転の角度の時系列に局所詳細釣り合いを当てはめた。その結果、360°回転で解放される化学自由エネルギーの大きさがATP3分子分に相当することが明らかになった。< …

    Meeting Abstracts of the Physical Society of Japan 72.1(0), 3242-3242, 2017

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  • Determination of Interface Structure of Disubstituted Benzene Single-Molecule Junction with Simultaneous Measurement of Current-Voltage Characteristic and Surface Enhanced Raman Scattering  [in Japanese]

    Suzuki Sho , Kaneko Satoshi , Kiguchi Manabu

    <p>単分子接合は分子素子への応用から近年注目を集めている。しかし、単分子接合の物性を大きく左右する電子状態と原子構造を明らかにした例は少ない。本研究では、単分子接合の界面構造を決定し、印加電圧が界面構造に与える影響を解明することを目的とした。実験は、単分子接合の電流電圧特性-表面増強ラマン散乱同時計測を室温大気中で行った。結果、2置換ベンゼン単分子接合が持つ吸着構造の異なる複数の伝導 …

    Meeting Abstracts of the Physical Society of Japan 72.1(0), 2619-2619, 2017

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  • Evaluation of the Electronic Structure of the Single-molecule Junction Based on Current-Voltage Measurement and Thermopower Measurement – Application to C60 Single-molecule Junction  [in Japanese]

    Isshiki Yuji , Komoto Yuki , Fujii Shintaro , Kiguchi Manabu

    <p>単分子物性の理解や単分子素子の開発ためには単分子接合の電子状態の解明は欠かせない。単分子レベルのIV特性・熱起電力測定によって金属と接合した分子のフェルミ準位近傍の電子状態の情報が得られる。本研究ではSTMを用いた熱起電力計測とI-V計測によって新たな電子状態決定法の開発を行った。今回はこれらによってAu-C60単分子接合の金のフェルミエネルギー近傍の電子状態の決定に成功した。& …

    Meeting Abstracts of the Physical Society of Japan 72.1(0), 2442-2442, 2017

    J-STAGE 

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