Search Results 1-20 of 2068

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Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy

Yokota Kenichi , Matsuda Kohei , Nakagomi Takahiro , Matsuda Kosuke , Itoh Hiroshi , Kurihara Isao , Matsusaka Yohji , Emoto Katsura , Hishida Tomoyuki , Oshida Takuma , Kobayashi Sakiko , Murai-Takeda Ayano , Miyashita Kazutoshi

… In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. …

Internal Medicine, 2021

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2

Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly

Fukunaga Kensaku , Dong Tao , Ishikawa Ryou , Kadota Kyuichi , Haba Reiji , Inoshita Naoko , Murao Koji , Imachi Hitomi , Sato Seisuke , Kobayashi Toshihiro , Yoshioka Yuki , Saheki Takanobu , Ban Natsuki , Urushihara Kurumi , Lyu Jingya

It is quite rare that Cushing's disease shows acromegaly, and no pharmacotherapy has yet been discussed. A 21-year-old woman was diagnosed with Cushing's disease and underwent trans …

Internal Medicine, 2021

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3

Current status of systemic therapies for advanced pancreatic neuroendocrine tumors [in Japanese]

今岡大 , 宮澤祥一 , 渡邊一雄 , 佐々木満仁 , 橋本裕輔 , 光永修一 , 澁木太郎 , 大鶴徹 , 林康平 , 池田公史

消化器・肝臓内科 = Gastroenterology & hepatology 7(6), 506-513, 2020-06

Ichushi Web
4

A Case of Intractable Pancreatic Fistula after Pancreatoduodenectomy, Successfully Cured by Fistulo-jejunostomy Directly under the Abdominal Wall [in Japanese]

久保秀文 , 渡邉孝啓 , 橋本憲輝 , 平木桜夫 , 福田進太郎 , 得能和久 , 河岡徹 , 為佐卓夫

… Conservative therapy such as fasting, TPN, and administration of somatostatin analogue failed to achieve complete healing of pancreatic fistula. …

山口医学 = Yamaguchi medical journal 69(2), 87-92, 2020-05

IR Ichushi Web
5

Treatment case of gallbladder and common bile duct stones by prolonged administration of lanreotide for acromegaly [in Japanese]

Koizumi Masaru , Sata Naohiro

… Lanreotide is a long acting somatostatin analogue and gallstones are reported in over 5% as a side effect. …

Tando 34(5), 890-896, 2020

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6

Small Cystic Pancreatic Neuroendocrine Neoplasm with Huge Liver and Bone Metastases

Yasuda Muneji , Takeda Shotai , Lee Minami , Hoshi Susumu , Hoshi Tomoko , Tanaka Yuichi , Miyajima Shinji , Takaya Haruo , Kajimura Kozo

… After the surgery, somatostatin receptor scintigraphy detected an occult lumbar spine metastasis. …

Internal Medicine 59(23), 3027-3032, 2020

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7

Medical treatment of unresectable malignant insulinoma in an elderly patient [in Japanese]

MATSUMOTO Kazuhide , ITO Tetsuhide , FUJIMORI Nao , SUEHIRO Yuta , MURAKAMI Masatoshi , TERAMATSU Katsuhito , TAKAMATSU Yu , TAKAOKA Takehiro , OONO Takamasa , IGARASHI Hisato

… Somatostatin receptor scintigraphy was positive in the pancreatic tumor and multiple liver metastases. … Surgical treatment was considered to be ineffective, and the patient was treated with somatostatin analog and diazoxide. …

Suizo 35(5), 429-438, 2020

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8

The Chemokine CXCL14-like Immunoreactivity Co-exists with Somatostatin, but not NPY in the Rat Dorsal Horn and Has Intimate Association with GABAergic Neurons in the Lateral Spinal Nucleus

Yamamoto Toshiharu , Sasaguri Kenichi , Mizumoto Natsuki , Suzuki Hirohumi

… In this study, we investigated the distribution of CXCL14 immunoreactive structures in the rat spinal cord and clarified the association of these structures with somatostatin, glutamic acid decarboxylase (GAD; … These CXCL14 immunoreactive structures were also immuno-positive for somatostatin, but were immuno-negative for GAD and NPY. …

ACTA HISTOCHEMICA ET CYTOCHEMICA 53(5), 121-129, 2020

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9

Prevalence, incidence, comorbidities, and treatment patterns among Japanese patients with acromegaly: a descriptive study using a nationwide claims database

Matsubayashi Keisuke , Kawakami Koji

… Between the first surgery and 365 days after diagnosis, 15% of the patients in this cohort received medical treatment as the secondary treatment, mostly with somatostatin analogs (83%). …

Endocrine Journal 67(10), 997-1006, 2020

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10

Differential effects of β-arrestin1 and β-arrestin2 on somatostatin receptors in murine AtT-20 corticotroph tumor cells

Kageyama Kazunori , Hagiwara Rie , Niioka Kanako , Takayasu Shinobu , Daimon Makoto

… Somatostatin receptor, a G protein-coupled receptor (GPCR), types 2 (SSTR2) and 5 (SSTR5) mRNA expression is greater than that of other SSTR subtypes in human corticotroph adenomas. …

Endocrine Journal, 2020

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11

Diagnostic significance of somatostatin receptor scintigraphy using 111In-pentetreotide for recurrence and staging of pulmonary carcinoid tumors: Two case reports [in Japanese]

Ishikawa Narumi , Okada Satoru , Kato Daishiro , Tsunezuka Hiroaki , Shimomura Masanori , Inoue Masayoshi

… Somatostatin receptor scintigraphy (SRS, Octreoscan®) using somatostatin analogues such as 111In-pentetreotide was introduced in Japan in 2015 and is available for the diagnosis and staging of carcinoid tumors that express somatostatin receptors.Case 1: A 77-year-old man developed subcarinal lymphadenopathy 6 years and 8 months after undergoing right middle lobectomy for a typical pulmonary carcinoid tumor (stage IA). …

The Journal of the Japanese Association for Chest Surgery 34(6), 654-660, 2020

J-STAGE Ichushi Web
12

Effect of developmental exposure to ethanol on hippocampal neurogenesis in rats [in Japanese]

TAKAHASHI Yasunori , YAMASHITA Risako , KIKUCHI Satomi , OKANO Hiromu , TAKASHIMA Kazumi , KOBAYASHI Mio , YOSHIDA Toshinori , SHIBUTANI Makoto

This study examined developmental exposure effect of ethanol (EtOH) on hippocampal neurogenesis in rats. Maternal animals were administered 0, 10 or 12.5% (v/v) EtOH via drinking water from g …

Annual Meeting of the Japanese Society of Toxicology 47.1(0), P-53E, 2020

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13

Developmental exposure effect of lead acetate on hippocampal neurogenesis in rats [in Japanese]

YAMASHITA Risako , TAKAHASHI Yasunori , KIKUCHI Satomi , OKANO Hiromu , TAKASHIMA Kazumi , KOBAYASHI Mio , YOSHIDA Toshinori , SHIBUTANI Makoto

This study examined developmental exposure effect of lead acetate (PbAc) on hippocampal neurogenesis in rats. Maternal rats were administered 0, 2,000, or 4,000 ppm PbAc via drinking water fr …

Annual Meeting of the Japanese Society of Toxicology 47.1(0), P-184, 2020

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14

A case of difficult to diagnose duodenal gastrinoma [in Japanese]

KIMURA Akie , INOUE Takeshi , NEBIKI Hiroko , YAMAGUCHI Nanako , HIRATA Naoto , SUEKANE Takehisa , YAMASAKI Tomoaki , MIURA Koutarou , MURATA Akihiro , FUKUSHIMA Hiroko

… High-level serum gastrin, endoscopic ultrasound, somatostatin receptor scintigraphy, and selective arterial calcium injection test were done. …

Nippon Shokakibyo Gakkai Zasshi 117(8), 706-712, 2020

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15

PYOGENIC GRANULOMA REQUIRING DIFFERENTIATION FROM NEUROENDOCRINE TUMOR: A CASE REPORT [in Japanese]

TOMIYASU Shinjiro , SASAKI Masato , TSUJI Akira , ICHIKAWA Ryo , KURAMOTO Kunitaka , IIZAKA Masayoshi , MIZUTA Kaori , KATAOKA Aya , YAMABE Satoshi , SUGIHARA Kazuaki

… Enhanced computed tomography and magnetic resonance imaging showed rich blood flow in the tumor, but somatostatin receptor scintigraphy showed absent accumulation of the isotope; …

GASTROENTEROLOGICAL ENDOSCOPY 62(5), 557-562, 2020

J-STAGE Ichushi Web
16

Prolonged survival in a patient with multiple liver metastases from a pancreatic neuroendocrine tumor treated with Peptide Receptor Radiotherapy (PRRT) [in Japanese]

KOBAYASHI Noritoshi , ICHIKAWA Yasushi , SHIMAMURA Takeshi , TAKEDA Yuuma , OHKUBO Naoki , TOKUHISA Motohiko , HIROSHIMA Yukihiko , GOTO Ayumu , TAKANO Shoko , ENDO Itaru

… Pathological findings showed a neuroendocrine tumor (WHO 2010 NET G2 ki67 6%), and immunohistochemically findings revealed that somatostatin receptor (SSTR) type 2 was positive for tumor membrane. …

Suizo 35(1), 97-103, 2020

J-STAGE Ichushi Web
17

Presence of aberrant adrenocorticotropic hormone precursors in two cases of McCune–Albright syndrome

Takayasu Shinobu , Makita Koshi , Kageyama Kazunori , Okawa Yuta , Oki Yutaka , Yamagata Satoshi , Asari Yuko , Terui Ken , Daimon Makoto

… No involvement of 11β-HSD1 by GH excess was suggested because basal levels of ACTH and cortisol showed no changes, even after therapy for acromegaly by somatostatin analogues. …

Endocrine Journal 67(3), 353-359, 2020

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18

BK channel is functionally expressed in neuroendocrine pancreatic tumor QGP-1 cells. [in Japanese]

Noda Sayuri , Suzuki Yoshiaki , Imaizumi Yuji , Yamamura Hisao

… The after hyperpolarization in action potential (AP) was depolarized by the treatment of PAX.These results suggest that BK channel contributes somatostatin secretion and malignancy in QGP-1 cells. …

Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-P-245, 2020

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19

Spying on neuromodulation by constructing new genetically encoded fluorescent sensors [in Japanese]

Li Yulong

… We have further expanded the repertoire of GRAB sensors for detecting monoamines, purinergic transmitters (e.g. adenosine, ADP and ATP) and neuropeptides (e.g. cholecystokinin, somatostatin and vasoactive intestinal peptide). …

Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-SL07, 2020

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20

Activation of ribosomal p70 S6 kinase by selective serotonin (5-HT)2B receptor agonist BW723C86 is mediated by epidermal growth factor/transforming growth factor-α receptor tyrosine kinase in primary cultures of adult rat hepatocytes. [in Japanese]

Kurihara Kazuki , Moteki Hajime , Ogihara Masahiko , Kimura Mitsutoshi

… channel blocker verapamil, somatostatin, and a specific p70 S6K inhibitor LY2584702 completely abolished the phosphorylation of p70 S6K induced by both 5-HT and BW723C86. …

Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 1-P-101, 2020

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