Search Results 1-20 of 24

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  • New research methods for stem cells that maintain hard tissue  [in Japanese]

    溝口 利英

    日本歯科医師会雑誌 72(8), 655-663, 2019-11

    Ichushi Web 

  • Prolonged release of iloprost enhances pulpal blood flow and dentin bridge formation in a rat model of mechanical tooth pulp exposure

    Limjeerajarus Chalida N. , Sonntana Seang , Pajaree Limothai , Kansurang Chansawang , Pitt Supaphol , Saowapa Thumsing , Prasit Pavasant

    … At 30 days, an increase of mineralized tissue formation and dentin bridge formation was observed in the iloprost and iloprost/PLGA microsphere groups. … In conclusion, this PLGA microsphere iloprost delivery system significantly increased dental pulp blood flow in a prolonged manner and increased tertiary dentin formation in this rat pulp injury model. …

    Journal of Oral Science 61(1), 73-81, 2019


  • Efficacy of Er:YAG Laser in Vital Pulp Therapy  [in Japanese]

    OKAMOTO Motoki , KOMICHI Shungo , WATANABE Masakatu , YAGI Kyoko , NARUSE Haruna , ITO Yuki , TAKAHASHI Yusuke , HAYASHI Mikako

    … Some literatures demonstrated that Er:YAG laser irradiation induced earlier and more frequent tertiary dentin formation compared with conventional rotary preparation. … Immunofluorescence staining against high mobility group box 1 (HMGB-1) and dentin sialophosphoprotein (DSPP) was performed using the samples of the day 3 and day 7 respectively. …

    Journal of Japanese Society for Laser Dentistry 29(1), 1-9, 2018

    J-STAGE  Ichushi Web 

  • Reactions of the Dentin-Pulp Complex to Calcium Hydroxide Paste in Rats

    Nishikawa Yuichiro , Matsuda Saeka , Nakayasu Yoshikazu , Toriya Jin , Yokoi Yukiko , Shoumura Masahito , Okafuji Norimasa , Kawakami Toshiyuki , Osuga Naoto

    … <p>In this study, we performed animal experiment using calcium hydroxide paste, a root canal filling material (Vitapex®, Neo Dental Chemical Products Co., Tokyo), on dentin-pulp complex and observed several tissue reactions. … A thick tertiary dentin was formed in the area where iodoform calcium hydroxide paste was directly applied. …

    Journal of Hard Tissue Biology 26(2), 169-176, 2017


  • Histochemical Characteristics of Tertiary Dentin Due to Calcium Hydroxide Paste in Rats

    Moriyama Keita , Matsuda Saeka , Matsuda Atsuko , Kida Akio , Mizushima Hidemoto , Mitsui Erina , Shoumura Masahito , Kawakami Toshiyuki , Osuga Naoto

    … Experimentally verifying this fact, Nishikawa et al revealed that bone-like dentin corresponding to tertiary dentin is rapidly formed when calcium hydroxide is applied directly to the pulp. … Utilizing the same experimental system, histochemical study of the newly formed hard tissue (reparative dentin) was carried out and the results thereof were reported. …

    Journal of Hard Tissue Biology 26(3), 285-288, 2017

    IR  J-STAGE  Ichushi Web 

  • Effect of an experimental adhesive resin containing multi-ion releasing fillers on direct pulp-capping

    KAWASHIMA Satoki , SHINKAI Koichi , SUZUKI Masaya

    … The purpose of this study was to evaluate pulpal healing and reparative dentin formation after 14 and 28 days in exposed rat pulp directly capped with an experimentally developed all-in-one adhesive containing surface reaction-type pre-reacted glass-ionomer (S-PRG) filler. … After 14 days, the experimental adhesives containing S-PRG fillers and the control group formed tertiary dentin around the exposed pulp. …

    Dental Materials Journal 35(3), 479-489, 2016


  • Gypsum-based biomaterials: Evaluation of physical and mechanical properties, cellular effects and its potential as a pulp liner

    LOW Amy , MOHD YUSOF Hamidah , REZA Fazal , ABDULLAH NURUL Asma , SRITHARAN Shaminea , HAANIA ZAIN ALI Niswathul , SUBHI AZEEZ Hasan , HUSEIN Adam

    … Excellent cellular viability with pure-GYP and Gyp-CHT, as well as increased ALP activities, suggested the possibility of tertiary dentin formation. …

    Dental Materials Journal 34(4), 522-528, 2015

    J-STAGE  Ichushi Web 

  • P-44 Application of N,N-dimethylaniline derivatives as coinitiator of photoinitiating system for dental adhesives  [in Japanese]

    Sakamoto T , Yamada B , Anraku T

    … Campherquinone (CQ) as a photoinitiator combined with a tertiary amine as a coinitiator has been employed for curing of dental resin under visible light irradiation. … The activities of the initiator systems were estimated from the initial tensile strength to bovine enamel and dentin. …

    The journal of the Japanese Society for Dental Materials and Devices 33(5), 430, 2014-09-20

    Ichushi Web 

  • The Use of Cone-beam Computed Tomography (CBCT) for Orientation of Root Canals: A Case Report of Acute Apical Periodontitis  [in Japanese]

    Kanako SHOJI , Hidetoshi SHIMAUCHI

    … Although we tried drainage via root canals to ease the acute pain, it was difficult to access root canals because of the thickly formed dentin made of secondary and tertiary dentin. …

    The Japanese Journal of Conservative Dentistry 57(2), 188-196, 2014

    J-STAGE  Ichushi Web 

  • Dentin Regeneration by Direct Pulp Capping using rhBMP-2

    YAMAJI Kozo , HORIKAWA Gen , NISHITANI Yoshihiro , IZAWA Shunji , YOSHIYAMA Masahiro

    … The purpose of this study was to evaluate the effect of direct pulp capping using recombinant human BMP-2 (rhBMP-2) on dentin regeneration. … In both groups, the covered materials were observed at 3 weeks after operation, while they had disappeared and the tertiary dentin formation was observed into the prepared cavity at 8 weeks after operation. …

    Journal of Oral Tissue Engineering 5(3), 145-149, 2008


  • Histochemical and immunocytochemical study on hard tissue formation in dental pulp during the healing process after tooth replantation in rat molars

    Tsukamoto-Tanaka Hiroko , Ikegame Mika , Takagi Ritsuo , Harada Hidemitsu , Ohshima Hayato

    … It has been assumed that dental pulp has the capacity to elaborate both bone and dentin matrix under the pathological conditions following tooth injury. … Three to seven days after operation, the ALP-positive region recovered from the root apex to the coronal pulp followed by HSP-25-positive reactions in the successful case that resulted in tertiary dentin formation. …

    Cell and tissue research = Cell and tissue research 325(2), 219-229, 2006-08


  • Dentin Regeneration by Direct Pulp Capping Using a Bioabsorbable Material

    ITOTA Toshiyuki , HAYASHI Hiroyuki , TASHIRO Yoko , TAKAGI Ryo , YAMAJI Kozo , SHINNO Yasuo , IZAWA Shunji , OMAE Masanori , YOSHIYAMA Masahiro , KOMASA Yutaka

    … The aim of this study was to investigate the effect of bioabsorbable material on the direct pulp capping to know whether this material has a function in dentin regeneration by bioabsorption.<BR>Class V cavities with the exposed pulp area were prepared on the buccal surface of first molars in young beagle dogs. …

    Journal of Oral Tissue Engineering 4(1), 17-24, 2006


  • Stimulation of Alkaline Phosphatase Activity by PGE2 through Induction of IGF-1 in Human Dental Pulp Cells

    Sakamoto Maki , Matsushima Kiyoshi , Yamazaki Muneyoshi

    … stimulates the formation of tertiary dentin through induction of IGF-1 and IGFBP-5 expressions in HDP cells. …

    International Journal of Oral-Medical Sciences 2(1), 33-38, 2004

    J-STAGE  Ichushi Web 

  • Involvement of Nitric Oxide in Tertiary Dentin Formation  [in Japanese]

    梅 予鋒 , 山座 孝義 , 平田 昌子 , 赤峰 昭文

    日本歯科保存学雑誌 46, 143, 2003-10-07

    Ichushi Web 

  • Study on the Experimental One Step Adhesion System.  [in Japanese]

    Hayakawa Tohru , Kikutake Kazuyo , Nemoto Kimiya

    … The water-soluble bonding agents containing acidic monomer, water soluble photo initiator QTX, tertiary amine, and water-soluble methacrylates were prepared, and evaluated their adhesiveness to tooth. … As an acidic monomer, 4-META or MDP was used.<BR>The tensile bond strengths between composite resin and bovine enamel or dentin were measured. …

    Adhesive Dentistry 18(3), 239-248, 2000


  • New Visible-light Initiator Systems for Adhesion of Resin to Dentin  [in Japanese]

    IKAKURA Kenji , KOJIMA Katsunori , KADOMA Yoshinori , IMAI Yohji

    … develop a new visible-light initiator system for adhesion of resin to dentin, we examined the curing time of MMA/PMMA resin and adhesive strength between the resin and dentin using the following new initiator systems:tertiary-butylperoxymaleic acid(MA), which contains the carboxylic acid group having an affinity with dentin, was combined with camphorquinone(CQ)or 7, 7-dimethyl-2, 3-dioxobicyclo[2.2.1]heptane-1-carboxylic acid(DDHCA)as a photosensitizer and dimethylaminoethyl …

    The Journal of the Japanese Society for Dental Materials and Devices 10(1), 72-76, 1991

    J-STAGE  Ichushi Web 

  • Adhesion of Self-curing Resins Containing Methacryloyloxybenzoic Acid Isomers to Tooth Substrates  [in Japanese]


    … systems such as benzoyl peroxide-tertiary aromatic amine with or without aromatic sulfinate, were employed, and when teeth were not treated.3-MBA may be the best for dental adhesive among the isomers because of its higher solubility to other monomers and superior adhesive stability estimated by long-term immersion and thermocycling tests.SEM revealed that the formation of the resin-infiltrated dentin layer is closely associated with the bond strength to treated dentin, and that MBA promoted the …

    The Journal of the Japanese Society for Dental Materials and Devices 7(2), 234-251, 1988

    J-STAGE  Ichushi Web 

  • Activation of the Wnt/β-catenin pathway and tissue inhibitor of metalloprotease 1 during tertiary dentinogenesis

    YOSHIOKA S. , Takahashi Yusuke , Abe Makoto [他]

    The journal of biochemistry 153(1), 43-50, 2013-01

    Ichushi Web  Cited by (1)

  • Effects of Heat Stress on the Growth and Differentiation Ability of Dental Pulp Derived Cell  [in Japanese]

    MOROTOMI Takahiko , KITAMURA Chiaki , TERASHITA Masamichi , MINAKAMI Masahiko , MATSUMOTO Noriyoshi , HARUNA Chieko , IZUMI Toshio , ANAN Hisashi

    … Odontoblast or odontoblast-like cells in dental pulp produce tertiary dentin in response to various irritations of pulpodentin as a defense reaction. …

    The Japanese Journal of Conservative Dentistry 55(5), 304-312, 2012

    J-STAGE  Ichushi Web  References (34)

  • Dentin regeneration by direct pulp capping using rhBMP-2

    YAMAJI K , HORIKAWA Gen , NISHITANI Yoshihiro , IZAWA Shunji , YOSHIYAMA Masahiro

    … The purpose of this study was to evaluate the effect of direct pulp capping using recombinant human BMP-2 (rhBMP-2) on dentin regeneration. … In both groups, the covered materials were observed at 3 weeks after operation, while they had disappeared and the tertiary dentin formation was observed into the prepared cavity at 8 weeks after operation. …

    J Oral Tissue Engin 5, 145-149, 2008

    Ichushi Web  Cited by (2)

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