Search Results 1-20 of 577

  • FRAGMENTS OF THE AGE OF SPATIAL ABANDONMENT : A SCENE CHRONICLE OF URBAN ARTIFACT IN JAPAN 2019  [in Japanese]

    渡辺 道也

    … A scene is an aggregate of countless fragments. … In this book, the fragments discovered during the Japan tour are classified into similar phenomena, given appropriate names and archetypes, and presented as a tool called "Fragments". …

    法政大学大学院紀要. デザイン工学研究科編 = Bulletin of graduate studies. Art and Technology (10), 1-8, 2021-03-24

    IR  DOI 

  • The Discovery of <Private man> : A New Approach to Leviathan  [in Japanese]

    竹内 真澄

    … Thomas Hobbes(1588~1679)was a revolutional thinker who criticizedthe political philosophy of anciant time and middle age. … According to Leviathan,liberty of <private man> … lacked in concept of premodern society. … as the key category of modern socety. …

    桃山学院大学社会学論集 = ST.ANDREW'S UNIVERSITY SOCIOLOGICAL REVIEW 54(2), 1-29, 2021-02-22

    IR 

  • Where Does Fuyuko Matsukata's "New World History" Lead Us? : A response to the review of my book "Sengoku Japan and the Age of Discovery"  [in Japanese]

    平川 新

    洋学 = Annals of the Society for the History of Western Learning in Japan : 洋学史学会研究年報 (28), 109-136, 2021

  • Exploratory studies on novel therapeutic targets for intraocular vascular lesions  [in Japanese]

    Hara Hideaki , Nakamura Shinsuke

    … <p>Diabetic retinopathy and exudative age-related macular degeneration (AMD) are representative diseases caused intraocular vascular lesions such as macular edema and/or neovascularization and are difficult to cure in many cases. … Currently, drugs targeting vascular endothelial growth factor (VEGF) have been developed and have shown excellent results in treating macular edema, but there are no drugs indicated for regression or inhibition of neovascularization itself. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 94(0), 3-S26-2, 2021

    J-STAGE 

  • Central Nervous System Developmental Regulation of Microglia <i>via</i> Cytokines and Chemokines  [in Japanese]

    Shigemoto-Mogami Yukari , Sato Kaoru

    … <p>Microglia are immune cells resident in the central nervous system (CNS). … It has been gradually clarified that microglia play various roles at the developmental stage of the CNS. … From embryonic to early postnatal age, microglia remove apoptotic cells by phagocytosis and refine the neural circuits by synaptic pruning. …

    YAKUGAKU ZASSHI 141(3), 359-368, 2021

    J-STAGE 

  • How Immanuel Kant viewed Japan  [in Japanese]

    宮永 孝

    … is comprised from the following sections:Preface1) The names of Japan 2) Guillaume Rubruquis (French friar in the 13th century) alluded to Japan 3) Marco Polo, a braggart, talked about Japan 4) The name of Polo(孛羅)found in the History of the Yuan Dynasty 5) The description of Japan's …

    社会志林 = Hosei journal of sociology and social sciences 67(3), 1-54, 2020-12

    IR  DOI 

  • Discovery of radiolarian fossils from the Samotogawa Formation of the Paleogene Muro Group in the Southern Shimanto Belt in Kii Peninsula, Southwest Japan  [in Japanese]

    鈴木 博之 , 山本 俊哉 , 別所 孝範

    … 中期始新世の後期から後期始新世(RP16-19)を示す.この群集は指標種の産出に基づくと,古 第三紀放散虫化石帯の単一の化石帯に限定されるものではなく,いくつかの化石帯にまたがることが 特徴である.Abundant radiolarian fossils were newly found from mudstone of the Samotogawa Formation of the Muro Group in the Southern Shimanto Belt in Kii Peninsula, Southwest …

    大阪市立自然史博物館研究報告 = Bulletin of the Osaka Museum of Natural History (74), 95-102, 2020-03-31

    IR  DOI 

  • URBAN FORMATION OF SHIMLA BY TRANSFORMATION OF RACIAL SEGREGATION  [in Japanese]

    KUBISHIRO Keigo , YUMINO Yasuhiro , YAMANA Yoshiyuki

    … <p> This study is positioned a part of the study that reveal the cultural heritage value of hill station by the comparison of the urban formation of Dalat built by France and Shimla built by the Britain.</p><p> The Western European powers' …

    Journal of Architecture and Planning (Transactions of AIJ) (769), 547-554, 2020-03

    J-STAGE  AIJ 

  • Re-discovery of Karl Friedrich Schinkel in the age of modernism  [in Japanese]

    尾関 幸

    立命館言語文化研究 31(4), 151-170, 2020-03

    IR  DOI 

  • Authenticated Language Through Games that Contribute to the Interest and Language Acquisition of Learners of English Speakers of Other Languages  [in Japanese]

    Yara Sabrina Kemaleddine

    … In this particular University classroom setting and in the classes being taught, have been placed in the lowest level in regards to English exposure with my class being their first interaction of a new language, taught purely in English. … These particular students in this study were first year Economic students and of Japanese ethnicity being taught at a Japanese University. …

    札幌学院大学人文学会紀要 = Journal of the Society of Humanities (107), 123-132, 2020-02-25

    IR 

  • How to Describe Early Modern Japan in Global Settings : Review of Arata Hirakawa, Warring-States Japan and the Age of Discovery  [in Japanese]

    松方 冬子

    洋学 = Annals of the Society for the History of Western Learning in Japan : 洋学史学会研究年報 (27), 103-123, 2020

  • Pre-cochlear implant habilitation  [in Japanese]

    Minami Shujiro

    <p>要旨: 先天性難聴児に対する人工内耳手術は, 世界的にも我が国においても, 低年齢化の傾向にある。新生児聴覚スクリーニングの導入により早期に難聴の診断が可能になったことと, 早期に人工内耳を行うことが音声言語獲得により良い成績をもたらすエビデンスが確立してきたからである。かつて2歳以上だった本邦の小児人工内耳適応基準は, 2014年に「適応年齢は原則 1 歳以上 (体重8kg以上 …

    AUDIOLOGY JAPAN 63(6), 489-493, 2020

    J-STAGE 

  • Development of Fluorescent Substrate for Glycan Processing Glycosidase, and Screening of the Novel Glycosidase Inhibitor

    Miura Kazuki , Hakamata Wataru

    … Recently, functional analysis of glycan-processing enzymes has actively been performed, and the enzymes are focused on novel drug targets. … However, previously reported inhibitors for the glycan-processing enzymes have encountered major problems. … Additionally, screening systems for the inhibitors of glycan-processing enzymes are lacking. …

    Trends in Glycoscience and Glycotechnology 32(190), E201-E204, 2020

    J-STAGE 

  • Development of Fluorescent Substrate for Glycan Processing Glycosidase, and Screening of the Novel Glycosidase Inhibitor  [in Japanese]

    Miura Kazuki , Hakamata Wataru

    <p>タンパク質の糖鎖修飾は様々な糖転移酵素および糖質加水分解酵素により行われ、これら酵素による糖鎖修飾は様々な生命現象の発現に重要な役割を果たしている。近年、糖鎖修飾に関与する酵素は創薬ターゲットとして注目されており、これら酵素に対する阻害剤の需要が高まっている。しかし、既知の糖鎖修飾酵素阻害剤は低い膜透過性など治療薬として展開するには大きな問題を抱えている。加えて、阻害剤探索のため …

    Trends in Glycoscience and Glycotechnology 32(190), J177-J180, 2020

    J-STAGE 

  • Construction and maintenance of a knowledge database to promote the cancer genome medicine  [in Japanese]

    KOHSAKA Shinji , KOYAMA Takafumi , SUNAMI Kuniko , SHIMOI Tatsunori , SHIBATA Taro

    <p>個々の患者の腫瘍のゲノム情報に基づき治療を選択する時代を迎え,2019年 6 月からがんの遺伝子パネル検査が保険診療で実施可能となり,個別化がん医療を加速させるための大きな一歩となった.</p><p>遺伝子パネル検査で検出された遺伝子バリアントの解釈に基づいて治療を提供するためには,遺伝子バリアントの解釈とそのエビデンスレベルを付記する「臨床的意義付け」の …

    Journal of the National Institute of Public Health 69(3), 260-273, 2020

    J-STAGE 

  • Review of Colorectal Cancer Examination Results in Male Workers by Occupation  [in Japanese]

    Yamaguchi Takako , Hisayasu Toshie , Orisaka Chieko , Kurozawa Youichi , Matsubayashi Shigeyuki , Miyata Akira , Koide Yasushi , Morichika Toshihiko , OoKawa Tomohisa , Takano Yuji , Takeuchi Youko , Nagao Yuki

    <p> 2012年4月から2017年3月までの5年間に、当協会で協会けんぽの生活習慣病予防健診を受診した35歳~74歳の男性の大腸がん検診(IFOBT 2日法)成績を職業別に比較・検討した。職業分類は日本標準職業分類の大分類をもとにした。職業欄が「未記入」を除いた健診受診者は164,652人、このうち大腸がん検診受診者は150,688人で、期間中92人に大腸がんが発見された。5年間の全 …

    Health Evaluation and Promotion 47(2), 334-344, 2020

    J-STAGE  Ichushi Web 

  • The Role of Lytic Polysaccharide Monooxygenases in Wood Rotting Basidiomycetes  [in Japanese]

    Kojima Yuka , Várnai Anikó , Eijsink Vincent G. H. , Yoshida Makoto

    <p>木材腐朽菌は、森林生態系における木質バイオマスの主要な分解者であり、セルラーゼや溶解性多糖モノオキシゲナーゼ(LPMO)などの多様な酵素を細胞外に分泌することで木材細胞壁中のセルロースを分解する。興味深いことに、褐色腐朽菌と呼ばれる木材腐朽菌の一群は、数種の例外を除いて、結晶性セルロースを分解するために重要なセルラーゼであるセロビオヒドロラーゼ(CBH)を欠損しているが、LPMO …

    Trends in Glycoscience and Glycotechnology 32(188), J111-J119, 2020

    J-STAGE 

  • The Role of Lytic Polysaccharide Monooxygenases in Wood Rotting Basidiomycetes

    Kojima Yuka , Várnai Anikó , Eijsink Vincent G. H. , Yoshida Makoto

    … <p>The group of filamentous fungi called wood rotting fungi comprises the main decomposers of woody biomass in forest ecosystems. … Interestingly, one particular group of wood-rotting fungi, called brown-rot fungi, lacks key cellulases for degrading crystalline cellulose, namely cellobiohydrolases (CBHs), with only a few exceptions. …

    Trends in Glycoscience and Glycotechnology 32(188), E135-E143, 2020

    J-STAGE 

  • Alteration of the protein levels and/or posttranslational modification of CRMP 2 (Collapsin Response Mediator Protein 2) in the peripheral blood samples from young schizophrenia patients  [in Japanese]

    Nomoto Munetaka , Yamashita Naoya , Jitsuki-Takahashi Aoi , Nakamura Haruko , Makihara Hiroko , Nakamura Fumio , Evan Y Snyder , Hirayasu Yoshio , Goshima Yoshio

    … CRMP2 (collapsin response mediator protein 2) is an intracellular protein that plays an important role in mediating axon guidance molecules, dendritic branching and spine formation through its phosphorylation at the serine 522 residue. … We examined protein levels in brain specimens of Schizophrenia and control patients. … Increased levels of total CRMP2 were found. … In many cases this increased CRMP2 lowered the p-CRMP2:total CRMP2 ratio. …

    Proceedings for Annual Meeting of The Japanese Pharmacological Society 93(0), 2-P-167, 2020

    J-STAGE 

  • Titanite Mineralization of Microbial Bioalteration Textures in Jurassic Volcanic Glass, Coast Range Ophiolite, California

    Izawa Matthew R. M. , Banerjee Neil R. , Shervais John W. , Flemming Roberta , Hetherington Callum J. , Muehlenbachs Karlis , Schultz Cynthia , Das Debarati , Hanan Barry B.

    … Volcanic glasses are rarely preserved in the rock record, and the quality of preservation generally declines with increasing age. … Records preserved in ancient basaltic glasses therefore provide important links between processes operating in the distant past, and those that are active on the Earth today. …

    Frontiers in Earth Science (7), 315, 2019-12-03

    IR 

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