Soejima Kenji
,
Mimura Noriko
,
Hirashima Masaki
,
Maeda Hiroaki
,
Hamamoto Takayoshi
,
Nakagaki Tomohiro
,
Nozaki Chikateru
… We identified a novel metalloprotease, which could be responsible for cleaving the Tyr842-Met843 peptide bond of von Willebrand factor (vWF). … This metalloprotease was purified from Cohn Fraction-I precipitate of human pooled plasma by the combination of gel filtration, DEAE chromatography, and preparative polyacrylamide gel electrophoresis in the presence of SDS. …
J-STAGE