放射線事故時におけるセシウム除去としてのプルシアンブルー  [in Japanese] Prussian Blue as an Agent for Decontamination of ^<137>Cs in Radiation Accidents  [in Japanese]

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Author(s)

    • 小林 信義 KOBAYASHI Nobuyoshi
    • 放射線医学総合研究所放射線障害医療部放射線障害診療・情報室 Division of Radiation Health, Section of Medical Information and Radiation Injuries, National Institute of Radiological Sciences
    • 山本 泰 YAMAMOTO Yasushi
    • 放射線医学総合研究所放射線障害医療部放射線障害診療・情報室 Division of Radiation Health, Section of Medical Information and Radiation Injuries, National Institute of Radiological Sciences
    • 明石 真言 AKASHI Makoto
    • 放射線医学総合研究所放射線障害医療部放射線障害診療・情報室 Division of Radiation Health, Section of Medical Information and Radiation Injuries, National Institute of Radiological Sciences

Abstract

Prussian blue, a blue pigment, belongs to the ferric cyanoferrate (II) group. It binds univalent metal ions, and the binding activity depends on their ionic radius. Prussian blue is not absorbed from the gastrointestinal tract in a significant amount. The cesium is entero-enteric cycled through the intestine. Prussian blue inhibits the reabsorption of the cesium. Many studies using experimental animals showed that the oral administration of Prussian blue increases the rate of the fecal excretion of radiocesium which results in shortening its biological half life. The accident in Goiania, Brazil, in 1987 showed that Prussian blue effectively accelerated the removal of radiocesium without toxicity. In the present review, we describe Prussian blue from a biological aspect and discuss its clinical application for the decontamination of cesium in radiation accidents.

Journal

  • Japanese Journal of Health Physics

    Japanese Journal of Health Physics 33(3), 323-330, 1998-09

    Japan Health Physics Society

References:  44

Cited by:  1

Codes

  • NII Article ID (NAID)
    10002137373
  • NII NACSIS-CAT ID (NCID)
    AN00228458
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03676110
  • NDL Article ID
    4585340
  • NDL Source Classification
    ZN36(科学技術--原子力工学・工業) // ZS45(科学技術--医学--放射線医学)
  • NDL Call No.
    Z16-696
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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