Stereoselective Synthesis of the LM Ring Moiety of Ciguatoxin: Reagent Control of Asymmetric Dihydroxylation

• Tohru Oishi

  Department of Chemistry, Graduate School of Science, Tohoku UniversitySendai

• Mitsuru Shoji

  Department of Chemistry, Graduate School of Science, Tohoku UniversitySendai

• Naomi Kumahara

  Department of Chemistry, Graduate School of Science, Tohoku UniversitySendai

• Masahiro Hirama

  Department of Chemistry, Graduate School of Science, Tohoku UniversitySendai

Abstract

Stereoselective synthesis of the LM ring moiety of ciguatoxin was achieved from (R)-(E)-1-benzyloxy-2-hydroxy-3-pentene via Ireland-Claisen rearrangement, iodolactonization, and reagent-controlled asymmetric dihydroxylation.

Journal

• Chemistry Letters

  Chemistry Letters 26 (9), 845-846, 1997-09-01

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360002219109406208
• NII Article ID: 10002614489
• NII Book ID: AA00603318
• DOI: 10.1246/cl.1997.845
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/26/9/845/56074067/cl.1997.845.pdf
• Data Source:
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  • CiNii Articles