Comparison of the Blood Clearance Tests of 99mTc-Phytate and Indocyanine Green in Liver-injured Dogs with D-Galactosamine.

• SHIBATA Hiroshi

  Department of Veterinary Pharmacology, Faculty of Agriculture, Yamaguchi University

• KOHNO Masahiro

  Department of Veterinary Pharmacology, Faculty of Agriculture, Yamaguchi University

Bibliographic Information

Other Title

• <SUB>D</SUB>-ガラクトサミン肝障害イヌにおける<SUP>99m</SUP>Tc-フィチン酸とインドシアニングリーンの血液クリアランス試験の比較
• Comparison of the Blood Clearance Tests

Abstract

The comparative study of the blood clearance tests of ^99mTc-Phytate (^99mTc-P) and indocyanine green (ICG) was undertaken in liver-injured dogs with D-galactosamine (GaIN) .<BR>The blood clearances of ^99mTc-P and ICG in dogs decreased with the increase in dose of GalN and with the time elapsed after GalN administration. As compared with the blood clearance test of ICG, the blood clearance test of ^99mTc-P in dogs was found to be more sensitive in detection of the hepatic dysfunction with mildly damaged stage, but to be relatively inaccurate in detection of the hepatic dysfunction with severely damaged stage induced by GaIN.

Journal

• RADIOISOTOPES

  RADIOISOTOPES 47 (11), 830-836, 1998

  Japan Radioisotope Association

Keywords

• technetium-99m-phytate
• indocyanine green
• blood clearance
• <SUB>D</SUB>-galactosamine
• hepatic dysfunction
• dog

Details

• CRID: 1390282679129614208
• NII Article ID: 130004383065
• NII Article ID: 10002683946
• NII Book ID: AN00351589
• DOI: 10.3769/radioisotopes.47.11_830
• ISSN: 18844111
• ISSN: 00338303
• NDL BIB ID: 4605195
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4605195
• Web Site: http://www.jstage.jst.go.jp/article/radioisotopes1952/47/11/47_11_830/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1999093052
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed