Studies for the Contamination of Long Lived Nuclides in Radiopharmaceuticals Used for Positron Emission Tomography (PET) on Clinical Examinations

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  • 臨床検査に使用されるPET用薬剤への長半減期核種の混入に関する測定
  • リンショウ ケンサ ニ シヨウ サレル PET ヨウヤクザイ エ ノ チョウ ハンゲンキカクシュ ノ コンニュウ ニ カンスル ソクテイ

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Abstract

Positron emission tomography (PET) which is widely used for clinical diagnosis employs very short lived nuclides. If there is no contamination of long lived nuclides in the radiopharmaceuticals, their radioactivity is decayed away in a short time. This means each material used dose not contain any radioactive nuclides thus should not be classified as radioactive waste. Therefore it is possible to make it simple and convenient to use the short lived radioactive materials. We have studied possible contamination of long lived nuclides in main radiopharmaceuticals used for PET. As a result, there is no long lived nuclides under limits of detection in the radiophamaceuticals exceptH215O.On production ofH215Othrough both direct method and reduction method, there is a trace contamination of tritium (3H) by the nuclear reaction of14N (d, 3H) 13N.However the amount of tritium is small enough to neglect any effect to human health.

Journal

  • RADIOISOTOPES

    RADIOISOTOPES 48 (2), 87-99, 1999

    Japan Radioisotope Association

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