アイスライニングによる凍結濃縮の実験的研究

• 山崎 浩

  藤沢薬品工業 (株) 生産技術研究所 大阪大学大学院基礎工学研究科後期課程

• 矢沢 久豊

  藤沢薬品工業 (株) 生産技術研究所

• 平田 雄志

  大阪大学大学院基礎工学研究科化学系専攻化学工学分野

書誌事項

タイトル別名

• Experimental Study on Freeze Concentration with Ice-lining.
• アイス ライニング ニヨル トウケツ ノウシュク ノ ジッケンテキ ケンキュウ

抄録

A new method of freeze concentration with ice-lining has been developed, which enables concentration of the solution to proceed only through the growth of an ice layer preformed on the inner wall of a agitated vessel crystallizer with cooling jacket. From the measurements of concentration and volume of the residual solution during the freezing process of cephalosporin C sodium solution, it is revealed that this method is superior for recovery of high concentrate compared with the simple method without ice-lining.<BR>The apparent partition coefficient of the solute was defined as the ratio of its concentration in the ice formed to that in the residual solution. The experimental results showed that the partition coefficient decreases with decreasing concentration of feed solution and the difference between the brine temperature and the freezing point of the feed solution, as well as with increasing impeller speed. In addition, it has been confirmed that this method results in little degradation to the substance contained in the concentrate compared with the ordinary method by evaporation.

収録刊行物

• 化学工学論文集

  化学工学論文集 24 (1), 30-36, 1998

  公益社団法人 化学工学会

キーワード

• ice
• crystallization
• freeze concentration
• agitation

詳細情報

• CRID: 1390001204508513664
• NII論文ID: 10002834871
• NII書誌ID: AN00037234
• DOI: 10.1252/kakoronbunshu.24.30
• COI: 1:CAS:528:DyaK1cXmslSrsA%3D%3D
• ISSN: 13499203
• ISSN: 0386216X
• ISSN: http://id.crossref.org/issn/0386216X
• NDL書誌ID: 4380939
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4380939
• Web Site: http://www.jstage.jst.go.jp/article/kakoronbunshu1975/24/1/24_1_30/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可