Erythrocyte Aggregation Enhanced by Hydrostatic Pressure.

  • TOYAMA Yoshiharu
    Department of Biological and Chemical Engineering, Faculty of Engineering, Gunma University
  • OHKAWA Shinji
    Department of Biological and Chemical Engineering, Faculty of Engineering, Gunma University
  • DOBASHI Toshiaki
    Department of Biological and Chemical Engineering, Faculty of Engineering, Gunma University
  • SAKANISHI Akio
    Department of Biological and Chemical Engineering, Faculty of Engineering, Gunma University

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Abstract

The effects of pressure on the aggregation of swine erythrocytes were investigated by monitoring the erythrocyte sedimentation rate under high pressure, up to 40 MPa. The aggregation of erythrocytes in plasma was propor-tionally enhanced by pressure, whereas aggregation of erythrocytes was not observed in saline solution up to 40 MPa. These results suggest that the adhesion energy between erythrocytes is not directly affected by pressure, but through a change in the interaction energy between plasma components and erythrocytes.

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