Organic Reactions and High Pressure. High Pressure-A Useful Parameter for Catalysis?

  • Reiser Oliver
    Institut für Organische Chemie, Universität Regensburg, Universität sstr

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  • High Pressure--a Useful Parameter for Catalysis?
  • High Pressure a Useful Parameter for Ca

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Abstract

The scope and limitation of high pressure for the catalysis of organic reactions is evaluated. This article focuses on Lewis acid (cycloadditions, epoxide openings, Horner-Wadsworth-Emmons reactions) and palladium catalyzed (Heck-reaction, [3+2] cycloadditions) reactions. Aspects of reactivity (turnover frequencies and turnover rates) as well as selectivity (chemoselectivity, regioselectivity, diastereo- and enantioselectivity) under the influence of pressure will be discussed.

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