Measurement of Active Oxygen from Photosensitizer Pumped by Q-switched Nd: YAG Laser

• Nagao Tomokazu

  Keio University

• Iino Toru

  Keio University

• Saito Akira

  Keio University

• Yamamoto Tsuyoshi

  Keio University

• Aizawa Katsuo

  Tokyo Medical College

• Minamitani Haruyuki

  Keio University

Bibliographic Information

Other Title

• Q-switched Nd: YAG laser光励起時における光感受性物質由来の活性酸素測定
• Q-switched Nd YAG laser ヒカリレイキジ ニ オケル ヒカリ カンジュセイ ブッシツ ユライ ノ カッセイ サンソ ソクテイ

Abstract

In this study, a doubled Q-switched Nd: YAG Laser (λ=532nm, FWHM=6nsec., repetition rate=10Hz) which has high peak power and lower thermal effect than that of continuous wave laser, was employed to investigate the production of active oxygen from photosensitzer. As the photosensitizer, Zinc coproporphyrin III (Zn CP-III) was prepared. The production of active oxygen from the photosensitizer was measured by method of luminol chemiluminescence. As the result, the waveform of luminol chemiluminescence was acquired. The peak wavelength of luminol chemiluminescence was approximately 430nm, The chemiluminescence intensity of luminol increased with increase in the Zn CP-III concentration and the pulse energy.

Journal

• IEEJ Transactions on Fundamentals and Materials

  IEEJ Transactions on Fundamentals and Materials 119 (3), 261-266, 1999

  The Institute of Electrical Engineers of Japan

Keywords

• 光線力学的治療
• パルスレーザ
• 活性酸素
• ポルフィリン
• ルミノール化学発光法

Details

• CRID: 1390282679575867520
• NII Article ID: 10004442033
• NII Article ID: 130006838948
• NII Book ID: AN10136312
• DOI: 10.1541/ieejfms1990.119.3_261
• ISSN: 13475533
• ISSN: 03854205
• NDL BIB ID: 4662810
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4662810
• Web Site: https://www.jstage.jst.go.jp/article/ieejfms1990/119/3/119_3_261/_pdf
• Data Source:
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  • NDL
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  • CiNii Articles
• Abstract License Flag: Disallowed