動脈血二酸化炭素分圧低下時の微小循環動態

DOI Web Site 被引用文献1件 参考文献35件

書誌事項

タイトル別名
  • Effect of hypocapnia on microcirculation
  • 動脈血二酸化炭素分圧低下時の微小循環動態--Rabbit Ear Chamber法を用いて
  • ドウミャクケツ 2サンカタンソ ブンアツ テイカジ ノ ビショウ ジュンカン
  • using rabbit ear chamber method
  • Rabbit Ear Chamber法を用いて

この論文をさがす

抄録

Using the rabbit ear chamber (REC) method, the author compared the effect of hypocapnia and that of normocapnia on cutaneous microcirculation of rabbits. Eight rabbits, weighting 3-4kg, were used for this study, which were anesthetized with pentobarbital and pancuronium. To maintain PaO2 at 100-150mmHg and PaCO2 at 20-25mmHg (HYPOCAPNIC GROUP), they were mechanically ventilated with air-O2 and regulated. After observing the circulation of arteriole during hypocapnia for 15-20 minutes, to induce normocapnia, 100% CO2 was added to the inspired gas stepwise until PaCO2 reached 35-45mmHg (NORMOCAPNIC GROUP). And the circulationof arteriole was observed during normocapnia for 15-20 minutes.<BR>No significant changes were observed in the blood pressure, heart rate and pulse pressure. However, significant change was observed in pH. During hypocapnia, the diameter, blood-flow velocity and blood-flow rate of the arterioles were markedly reduced (p<0.05).<BR>This study using REC has shown that hypocapnia causes cutaneous microcirculatory changes and increase systemic vascular resistance.

収録刊行物

被引用文献 (1)*注記

もっと見る

参考文献 (35)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ