Transient Expression of CD20 Antigen(Pan B Cell Marker)in Activated Lymph Node T Cells
-
- MURAYAMA Yuichi
- Institute of Basic Medical Sciences, University of Tsukuba
-
- MULAI Ryozaburo
- Tsukuba Primate Center for Medical Science, The National Institute of Health
-
- SATA Tetsutaro
- Laboratory of Pathology, AIDS Research Center, The National Institute of Health
-
- MATSUNAGA Satoko
- Institute of Basic Medical Sciences, University of Tsukuba
-
- NOGUCHI Atsuo
- Institute of Basic Medical Sciences, University of Tsukuba
-
- YOSHIKAWA Yasuhiro
- Tsukuba Primate Center for Medical Science, The National Institute of Health
Search this article
Abstract
In contrast to the case of peripheral T cells, the surface expression of CD20 antigen and the expression of CD20 mRNA in monkey lymph node (LN) T cells underwent a noticeable increase when they were cultured with mitogen and interleukin-2 (IL-2). To confirm in vivo regulation of CD20 expression during the activation of LN T cells, we examined LNs derived from monkeys experimentally inoculated with simi-an immunodeficiency virus (SIV). Significant expression of CD20 antigen was detected in the T cells of the LNs at the stage of lymphadenopathy. These findings suggest that lymphocyte activation in the LNs induced expression of the CD20 molecule in some T cells.
Journal
-
- MICROBIOLOGY and IMMUNOLOGY
-
MICROBIOLOGY and IMMUNOLOGY 40 (6), 467-471, 1996-06-20
Center For Academic Publications Japan
- Tweet
Keywords
Details
-
- CRID
- 1571980074184846592
-
- NII Article ID
- 10004893212
-
- NII Book ID
- AA00738350
-
- ISSN
- 03855600
-
- Text Lang
- en
-
- Data Source
-
- CiNii Articles