書誌事項
- タイトル別名
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- Changes in serum anti-Helicobacter pylori IgG antibody, pepsinogen I, and pepsinogen II after eradication therapy of Helicobacter pylori.
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抄録
To investigate the changes in serum anti-Helicobacter pylori IgG antibody (HP Ab), pepsinogen I (PG I), pepsinogen II (PG II), and pepsinogen I/II ratio (PG I/II) after eradication therapy of Helicobacter pylori (HP), we studied 78 patients with HP-positive peptic diseases. They received combination therapy (proton pump inhibitor+amoxicillin: n=17, proton pump inhibitor+amoxicillin+clarithromycin: n=61). In the 68 patients in whom HP was eradicated, HP Ab, PG I, and PG II decreased and PG I/II increased significantly after eradication. Especially, the decrease in PG II and the increase in PG I/II were rapid and remarkable, found 2 months after the beginning of eradication therapy, and then continued. On the other hand, in the patients in whom HP was not eradicated, HP Ab and PG I/II did not change significantly, while PG I and PG II temporarily increased at the end of administration of proton pump inhibitor. In conclusion, it seems that the measurement of PG II and PG I/II is useful for the early detection of HP eradication.
収録刊行物
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- 日本消化器病学会雑誌
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日本消化器病学会雑誌 94 (11), 723-729, 1997
一般財団法人 日本消化器病学会
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詳細情報 詳細情報について
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- CRID
- 1390282681372688000
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- NII論文ID
- 10005019707
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- NII書誌ID
- AN00192124
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- COI
- 1:STN:280:DyaK1c%2FlvVaqtw%3D%3D
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- ISSN
- 13497693
- 04466586
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- PubMed
- 9396326
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可