A Clinicopathological Study of Aspirin-Induced Asthma.

• FUJII Megumi

  Hyogo Collage of Medicine

• FUKAZAWA Keijiro

  Hyogo Collage of Medicine

• OGASAWARA Hiroshi

  Hyogo Collage of Medicine

• SAKAGAMI Masafumi

  Hyogo Collage of Medicine

Bibliographic Information

Other Title

• アスピリンぜん息症例鼻茸の臨床病理学的検討

Abstract

Aspirin-induced Asthma (AIA) is characterized by three clinical findings; asthma, aspirin intolerance and nasal polyps. We reported the outcome of endoscopic sinus surgery (ESS) in 12 patients with AIA, and compared the number of eosinophils in paraffin sections of nasal polyps between AIA and non-AIA patients. All ESSs were safely performed using drip injection of steroids and local anesthesia with 2% pure Xylocaine® during surgery. They improved asthma and nasal symptoms in all patients. Eosinophils in nasal polyps from AIA patients were significantly more abundant than those in nasal polyps of non-AIA patients (p<0.01). AIA-patients showed significantly more peripheral blood eosinophils than non-AIA patients (p<0.05). The role of eosinophils in nasal polyps of AIA and surgical notes for treatment of AIA were discussed.

Journal

• Practica Oto-Rhino-Laryngologica

  Practica Oto-Rhino-Laryngologica 91 (10), 993-997, 1998

  The Society of Practical Otolaryngology

Keywords

• aspirin induced asthma (AIA)
• nasal polyp
• eosinophil

Details

• CRID: 1390282679236230528
• NII Article ID: 10005032286
• NII Book ID: AN00107089
• DOI: 10.5631/jibirin.91.993
• ISSN: 18844545
• ISSN: 00326313
• Web Site: https://search.jamas.or.jp/link/ui/1999130315
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed