傾斜機能材料  生体応用に向けた傾斜機能材料の作製と特性

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タイトル別名
  • Fabrication and Properties of FGM for Biomedical Application.
  • セイタイ オウヨウ ニ ムケタ ケイシャ キノウ ザイリョウ ノ サクセイ ト トクセイ

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Functionally graded implants composed of titanium (Ti) and hydroxyapatite (HAP) were fabricated by powder metallurgy to satisfy both mechanical properties and biocompatibilities. Concentration gradience was formed either by sedimentation in solvent liquid or by packing dry powders into mould, followed by compressing and sintering. Electric furnace heating, high frequency induction heating and spark plasma sintering (SPS) methods were used for sintering. SPS could make the stable functionally graded materials (FGM) with the gradual change of concentration in the longitudinal direction from pure Ti to 100%HAP (Ti/100HAP). Animal implantation tests were done to evaluate biocompatibility in soft tissue and osteogenesis in hard tissue. Histological observation by optical microscopy using the thinly sectioned, stained specimens and elemental mapping by EPMA and XSAM (X-ray scanning analytical microscope) using the unstained block specimens showed that the tissue reacted gradiently in response to the graded composition of FGM implant. This implies the possibility to control the tissue response through the gradient function of FGM.

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