Nucleotide Sequence Analysis of Recent Epidemic Strains of Enterovirus 70

• YAMAZAKI Kenji

  Laboratory of Virology, Osaka Prefectural Institute of Public Health

• OISHI Isao

  Laboratory of Virology, Osaka Prefectural Institute of Public Health

• MINEKAWA Yoshiichi

  Laboratory of Virology, Osaka Prefectural Institute of Public Health

抄録

Nucleotide sequences of the genome of enterovirus 70 (EV70) isolated in Osaka in 1993 were determined, and compared with those of the past epidemic strains. Nucleotide substitution rates in 332bp, 174bp, and 178bp of the genes encoding viral protein (VP)1, VP2, or VP3 were 9.0, 7.5, and 5.6% between Kumoi-2/93 and J670/71, respectively. Likewise, the putative amino acid substitution rates were 1.8, 0, and 0%. It seems that the epidemic strains of EV70 in Japan have been evolving at a constant high nucleotide substitution rate but almost all the substitutions were synonymous.

収録刊行物

• Microbiology and immunology

  Microbiology and immunology 39 (6), 429-432, 1995-06-20

  財団法人 学会誌刊行センター

キーワード

• RT-PCR
• Sequencing
• Enterovirus 70

詳細情報

• CRID: 1572824499197918720
• NII論文ID: 10005200790
• NII書誌ID: AA00738350
• ISSN: 03855600
• Web Site: http://chemport.cas.org/cgi-bin/sdcgi?APP=ftslink&action=reflink&origin=jstage2&version=1.0&coi=1:CAS:528:DyaK2MXmvVOru7Y%3D&md5=c18e45441805d7a67bff422e31ed154c
• Web Site: https://search.jamas.or.jp/link/ui/1996035574
• 本文言語コード: en
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