書誌事項
- タイトル別名
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- Multimodal evoked potentials in patients with multi-infarct dementia and Alzheimer's disease.
- -Alzheimer病との比較-
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The auditory event-related potential (ERP), somatosensory evoked potentials (SEP), visual evoked potential (VEP) and brainstem auditory evoked potential (BAEP) were studied in 15 patients with Alzheimer's disease (AD), 16 patients with multi-infarct dementia (MID) due to subcortical infarctions and 15 normal control subjects. Both groups with dementia showed significant prolongation of the N200 and P300 latencies of the ERP as compared with those of the normal controls. In addition, patients with AD revealed significant prolongation of the P200 latency. Patients with MID showed significant prolongation of N13-N20 and N20-P40 of the SEP as compared with the normal controls, while patients with AD revealed only significant prolongation of N20-P40. There were no significant differences in P100 latency of the VEP among the three groups. The interpeak latencies between the I and V waves of the BAEP in patients with AD and MID were significantly longer than that of the normal controls. Thus, electrophysiological differences between MID and AD were noted in the ERP and SEP. The present results indicate that these two diseases with dementia exhibit abnormalities of evoked potentials, and also have some electrophysiological differences, which may be related to the underlying pathogenetic mechanisms. Measurement of multimodal evoked potentials, particularly of the SEP and ERP, may be helpful for the differential diagnosis of AD and MID.
収録刊行物
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- 脳卒中
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脳卒中 17 (4), 325-331, 1995
一般社団法人 日本脳卒中学会
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詳細情報 詳細情報について
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- CRID
- 1390001204639657216
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- NII論文ID
- 130003631182
- 10005234706
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- NII書誌ID
- AN0020186X
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- ISSN
- 18831923
- 09120726
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可