上顎洞平滑筋肉腫例

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  • The Case of a Leiomyosarcoma of the Maxillary Sinus.

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The case of a leiomyosarcoma which developed in the right maxillary sinnus region is reported rare. A 66-year-old male presented with a chief complaint of recurrent epistaxis from the right nasal cavity. Upon examination, a dark red tumor was found in the right nasal cavity and the gingiva. An X-ray examination revealed ill-defined densities in the right maxillary sinus and ethmoid sinus. Following a biopsy, this case was diagnosed as a poorly differentiated squamaous cell carcinoma. CDDP arterial injection and PEP continuous subcutaneous injection were first performed on the right opened maxillary sinus and 50Gy was then irradiated on the right maxillary portion. However, the tumor remained in ethmoid sinus and the lower wall outside of the maxillary sinus, and therefore a subtotal extirpation of the upper jaw was performed on a wide range of area including the foregoing portions. An immunohistopathological examination led to the definitive diagnosis of a leiomyosarcoma. After he was discharged from the hospital, he experienced a local recurrence of the tumors.<br>Since the tumor grew despite radical chemical therapy such as CDDP, THP-ADM and CPM, the extirpation of a wide range of area including the right hemipalate was carried out. Furthermore, CDDP, VP-16 and CPM chemotherapies were performed, but the patient still died.

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