クラミジア性子宮頸管炎に対する経口キノロン薬balofloxacinの臨床的検討

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  • Clinical efficacy of balofloxacin, a newly oral quinolone, against chlamydial cervicitis

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Clinical studies were carried out on balofloxacin (BLFX), a new fluoroquinolone antibiotic, against chlamydial infections in patients with cervicitis.<BR>BLFX was administered oraly 200 or 400mg (b. i. d.) for 7-10 days. Two patients with equivocal evidence of chlamydial infection were excluded. Chlamydia trachomatis DNA or antigen disappeared in 8 cases after the treatment, and the bacteriological response was evaluated as eradicated in 8 cases. With reference to the clinical response, the symptoms of infection improved or disappeared in these cases, and the efficacy rate was therefore evaluated as 100%. No adverse reactions or abnormalities in laboratory findings due to the treatment were recognized.

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