An Adult Case of Neurohypophyseal Ectopy Presenting ACTH Deficiency and Partial GH Deficiency.

• TAKAMURA TOSHINARI

  Department of Internal Medicine, Kanazawa Red Cross Hospital First Department of Internal Medicine, School of Medicine, Kanazawa University

• OHSAWA KENSOU

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• NISHIMURA YASUYUKI

  Department of Internal Medicine, Kanazawa Red Cross Hospital

• YAMAGISHI SHOICHI

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• KOMATSU YOSHIKAZU

  Department of Internal Medicine, Kanazawa Red Cross Hospital

• IWATA AKIRA

  Department of Internal Medicine, Kanazawa Red Cross Hospital

• OSADA SEIMEI

  Department of Internal Medicine, Kanazawa Red Cross Hospital

• NAGAI YUKIHIRO

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• MIYAKOSHI HISATSUCU

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• KOBAYASHI KEN-ICHI

  First Department of Internal Medicine, School of Medicine, Kanazawa University

抄録

A case of ACTH deficiency and partial GH deficiency associated with neurohypophyseal ectopy is described. A 42-year-old woman of short stature was admitted for hypoglycemic coma. The patient had hypocortisolemia, an increase in urinary 17-OHCS after consecutive injections of ACTH-Z, and a low plasma ACTH level which showed no response to corticotropin-releasing factor. This indicated the presence of ACTH deficiency. The plasma GH level showed a blunted response to insulininduced hypoglycemia, but its response to GRF was preserved. Other hypothalamo-pituitary axes were intact. T1-weighted magnetic resonance imaging demonstrated ectopic neurohypophyseal tissue and a tiny anterior pituitary remnant. ACTH deficiency and partial GH deficiency might have developed as a consequence of pituitary stalk injury and inadequate regeneration of the anterior lobe.

収録刊行物

• Endocrine Journal

  Endocrine Journal 42 (1), 83-88, 1995

  一般社団法人 日本内分泌学会

キーワード

• ACTH deficiency
• Partial GH deficiency
• Neurohypophyseal ectopy

詳細情報

• CRID: 1390282681275910912
• NII論文ID: 130003549513
• NII論文ID: 10005553467
• NII書誌ID: AA10901436
• DOI: 10.1507/endocrj.42.83
• COI: 1:STN:280:ByqA38zgsFQ%3D
• ISSN: 13484540
• ISSN: 09188959
• PubMed: 7599703
• Web Site: http://www.jstage.jst.go.jp/article/endocrj1993/42/1/42_1_83/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1996105583
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可