歯性感染症から急性化膿性縦隔炎に進展した糖尿病の1例

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  • Fatal Descending Necrotizing Mediastinitis from Odontogenic Infection in a Diabetic Patient.

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A 63-year-old man with diabetes mellitus developed a high fever, and swelling of the right cheek due to periodontal infection. He was transferred to our hospital as the symptoms worsened and were accompanied by neck swelling, dyspnea, confusion, and a high blood glucose level despite antibiotic therapy. Chest radio graphy and computed tomography revealed a gas-forming mediastinal abscess, pleural and pericardial effusion, and cervical cellulitis. His diseases were diagnosed as mediastinitis, peripharyngitis, and cervical cellulitis from odontogenic infection associated with a diabetic hyperosmolar state. He was treated by administration of antibiotics, gamma globulin, and granulocyte colony-stimulating factor, surgical drainage, and intermittent flushing of the mediastinal cavity with 0.2%povidone-iodine, along with fluid transfusion and insulin administration. Tracheotomy and mechanical ventilation were also required. Although bronchopneumonia developed during his hospitalization, overall treatment was successful. After discharge, blood HbA1c levels have been maintained at between 6. 0 and 7.0%by diet therapy. It should be noted that mediastinitis may occur as a rare complication of oropharyngeal infection in patients with underlying disorders such as diabetes mellitus.

収録刊行物

  • 糖尿病

    糖尿病 40 (8), 557-562, 1997

    一般社団法人 日本糖尿病学会

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