原因不明感音難聴患者の免疫血清学的検討

• 高橋 光明

  旭川医科大学耳鼻咽喉科学教室

• 坂田 文

  旭川医科大学耳鼻咽喉科学教室

• 海野 徳二

  旭川医科大学耳鼻咽喉科学教室

• 北南 和彦

  釧路労災病院耳鼻咽喉科

• 執行 寛

  釧路労災病院耳鼻咽喉科

書誌事項

タイトル別名

• Immunological Abnormalities in Patients with Etiology Unknown Sensorineural Hearing Loss.

抄録

An immunological study was carried out in 50 patients with etiology unknown sensorineural hearing loss, including the following: 12 low tone deafness, 7 sudden deafness, 8 unilateral deafness, 7 idiopathic bilateral progressive sensorineural hearing loss and 14 other bilateral sensorineural hearing loss. Twenty five out of 50 of the cases demonstrated immunological abnormalities. A full array immunological tests were performed with the following results. High immnunoglobulin titers showed in 18 out of 50 cases. Six cases were positive for antinuclear antibody. The anti-DNA antibody assay revealed high titers in 2 cases. Also, anti-rheumatoid factor antibody assay showed high titers in 6 cases while abnormal values of complements in serum were detected in 6 cases, though an immune complex was demonstrated in only one case. Also, it was noted that six patients with immunological abnormalities have autoimmune diseases. The above results indicated that some cases of etiology unknown sensorineural hearing loss may have an immunological link.

収録刊行物

• 日本耳鼻咽喉科学会会報

  日本耳鼻咽喉科学会会報 101 (10), 1260-1265, 1998

  一般社団法人 日本耳鼻咽喉科頭頸部外科学会

キーワード

• 感音難聴
• 免疫血清学
• 自己免疫疾患

詳細情報

• CRID: 1390001205005408512
• NII論文ID: 10005598939
• NII書誌ID: AN00191551
• DOI: 10.3950/jibiinkoka.101.10_1260
• ISSN: 18830854
• ISSN: 00306622
• PubMed: 9838794
• Web Site: https://search.jamas.or.jp/link/ui/1999081166
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可