超音波内視鏡による早期胃癌の術前深達度診断に関する検討

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  • Accuracy Estimation of Endoscopic Ultrasonography for Assessing theDepth of Invasion in Early Gastric Cancer.

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The significance of local therapies for early gastric cancer was studied with regard to curability from the viewpoint of accuracy of endoscopic ultrasonography (EUS) for preoperatively assessing the depth of cancer invasion. EUS was performed in 56 patients with early gastric cancer. The overall accuracy rate of EUS was 66.1%. Ten patients with mucosal cancer had been overdiagnosed as suffering invasion into the submucosa, and 9 with submucosal cancer had been underdiagnosed as having mucosal cancer. In the latter, 8 were found to have minute invasion into the submucosa (sm1). Thus it seemed difficult to discriminate between mucosal cancer and sm1. A large sample of submucosal cancers was classified into three groups by the degree of invasion into the submucosa, sm1, sm2 and sm3, and the rates of lymph node metastasis were investigated. The sample number was 223 submucosal cancers which had been resected in our department since 1975. The metastatic rates in regional lymph nodes were 11.1%, 20.8% and 18.9% for sm1-sm3, respectively. On the other hand, that of mucosal cancer was 0.5%. The rate in sm1 was clearly higher than that in mucosal cancer. In order to carry out local therapies for early gastric cancer, reliable differential diagnosis of mucosal and submucosal cancers should be supported. Although promising, EUS still does not provide sufficient discrimination between mucosal cancer and sm1. Therefore, the attending physician should avoid local therapies unless he or she can make a definite preoperative discrimination between the two.

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