The effect of autologous platelet concentrate(Pcon) on pulmonary function after cardiopulmonary bypass.

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  • 開心術における自己濃厚血小板血しょう(Platelet concentrate;Pcon)の有用性  術後呼吸機能温存効果に関する臨床的検討
  • ―術後呼吸機能温存効果に関する臨床的検討―

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Abstract

The beneficial effect of platelet-leukocyte plasmapheresis on postbypass pulmonary function was evaluated in a prospective, randomized manner. The study involved 25 patients undergoing coronary artery bypass surgery with harvest of platelet concentrate (Pcon) and a control group of 25 patients without harvest of Peon. Pcon was harvested before systemic heparinization and was reinfused after cardiopulmonary bypass. Both oxygenation index and Aa-DO2 on ICU arrival and extubat ion were significantly better in the Peon group than in the control group. Leukocyte counts on the 1st and 2nd postoperative day were significantly lower in the Peon group than in the control group. These data suggest that platelet and leukocyte protection by Peon technique results in preservation of pulmonary function after cardiopulmonary bypass.

Journal

  • Jinko Zoki

    Jinko Zoki 27 (2), 398-401, 1998

    JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

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