書誌事項
- タイトル別名
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- Study of the EDA(+) fibronectin recognition structure on heparin.
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抄録
Study of the EDA (+) fibronectin recognition structure on heparin. We carried out research into an absorber to remove EDA (+) fibronectin (EDA (+) FN) from the blood by using heparin. The elucidation of the EDA (+) FN recognition structure of the heparin is necessary for the development of the effective material. In this study, the examination of recognition structure for EDA (+) FN was carried out by using desulfate heparin and the heparin oligomer. The association constant (KA) of EDA (+) FN and the heparin decreased gradually (1.0E+8→1.0E+7M-1) with desulfate treatment. There was hardly the change in KA with the decline of the molecular weight. As for the EDA (+) FN recognition structure of the heparin, our results showed that it was a low molecular weight level (less than MW=1.0E+3). We also found that the peculiar arrangement structure was not necessary.
収録刊行物
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- 人工臓器
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人工臓器 28 (1), 191-195, 1999
一般社団法人 日本人工臓器学会
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詳細情報 詳細情報について
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- CRID
- 1390001204955008896
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- NII論文ID
- 10005943550
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- NII書誌ID
- AN00120167
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- ISSN
- 18836097
- 03000818
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可