真菌感染に対する生体防御能

  • 安部 茂
    帝京大学医学部微生物学教室 帝京大学医真菌研究センター
  • 山口 英世
    帝京大学医学部微生物学教室 帝京大学医真菌研究センター

書誌事項

タイトル別名
  • Host Defense Mechanisms against Fungal Infections.

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抄録

Recent advances in the research on host defense mechanisms against infections with Candida and Aspergillus were reviewed. Modes of the defense mechanisms were divided into three phases by the different physiological circumstances surrounding the fungi: 1, the exocrine fluid in which fungi exist on the mucosal membranes; 2, the tissues invaded by fungi with the circulating blood; and 3, the limited lesions where fungi continue to be alive with a restricted blood flow. In each defense mechanism, the roles of the endogenous antifungal substances such as lactoferrin, defensins and calprotectin and leukocytes were discussed.

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