Steroid Pulse Therapy in Lupus Cystitis.

DOI Web Site PubMed 被引用文献7件 参考文献18件
  • SEGAWA Chikako
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • WADA Takashi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • FURUICHI Kengo
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • TAKASAWA Kazuya
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • YOKOYAMA Hitoshi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • KOBAYASHI Ken-ichi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University

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A middle-aged woman with lupus cystitis showed no other symptoms of lupus vasculitis. Cystoscopic findings revealed mucosal hemorrhage and hyperemia. Histological studies of the bladder showed mucosal edema, inflammatory cellular infiltration and the deposition of immune complexes along the vessels. She was treated with a combination of intravenous methylprednisolone pulse therapy and oral prednisolone. Cystoscopy and histological findings showed appreciable improvement. Elevated urinary levels of chemokines such as interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF) decreased during convalescence. These results suggest that the early diagnosis and treatment with steroid pulse therapy achieves improvement of an unusual vasculitis symptom, lupus cystitis.<br>(Internal Medicine 35: 155-158, 1996)

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  • Internal Medicine

    Internal Medicine 35 (2), 155-158, 1996

    一般社団法人 日本内科学会

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