Crohn's Disease Associated with Growth Hormone Secretory Dysfunction.

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  • OGURA Toshio
    the Third Department of Internal Medicine, Okayama University Medical School
  • KAGEYAMA Jingo
    the School of Health Sciences Okayama University
  • ITANO Yasuo
    the Third Department of Internal Medicine, Okayama University Medical School
  • YAMAUCHI Takayoshi
    the Third Department of Internal Medicine, Okayama University Medical School
  • OISHI Tetsuya
    the Third Department of Internal Medicine, Okayama University Medical School
  • AITA Tetsushi
    the Third Department of Internal Medicine, Okayama University Medical School
  • HAYAKAWA Nobuhiko
    the Third Department of Internal Medicine, Okayama University Medical School
  • OGASA Takashi
    the Third Department of Internal Medicine, Okayama University Medical School
  • OTA Kosuke
    the Third Department of Internal Medicine, Okayama University Medical School
  • OTA Zensuke
    the Third Department of Internal Medicine, Okayama University Medical School
  • HASHIMOTO Kozo
    the Second Department of Internal Medicine, Kochi Medical School

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Abstract

A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.<br>(Internal Medicine 34:112-117, 1995)

Journal

  • Internal Medicine

    Internal Medicine 34 (2), 112-117, 1995

    The Japanese Society of Internal Medicine

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